Best TWAS P=9.9e-10 · Best GWAS P=2.6e-12 conditioned to 0.000601
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Pancreas | ITGB8 | 0.26 | 0.14 | lasso | 6 | 0.14 | 2.5e-06 | 5.9 | 6.0 | 2.4e-09 | 0.87 | 0.39 | 0.60 | FALSE |
2 | GTEx | Pancreas | CTA-293F17.1 | 0.45 | 0.40 | enet | 10 | 0.40 | 3.3e-18 | 5.9 | 6.1 | 9.9e-10 | 0.85 | 0.44 | 0.56 | TRUE |