[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr7:73,425,238-74,494,207

Best TWAS P=2.47e-08 · Best GWAS P=3.3e-13 conditioned to 3.78e-12

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Skin Sun Exposed Lower leg	GTF2IRD2	0.07	0.04	lasso	2	0.05	5.2e-05	5.4	5.6	2.5e-08	0.06	0.01	0.96	TRUE
9	GTEx	Thyroid	GTF2IRD2	0.08	0.07	lasso	1	0.04	2.4e-04	5.4	5.4	8.1e-08	0.07	0.01	0.94	FALSE
6	GTEx	Nerve Tibial	GTF2IRD2	0.08	0.09	lasso	2	0.08	5.4e-06	5.4	5.3	9.1e-08	0.07	0.01	0.98	FALSE
1	GTEx	Artery Aorta	STAG3L2	0.18	0.18	lasso	6	0.16	3.0e-09	5.4	-5.3	1.0e-07	-0.07	0.01	0.99	FALSE
4	GTEx	Cells Transformed fibroblasts	STAG3L2	0.18	0.16	lasso	5	0.16	7.5e-12	5.4	-5.2	1.6e-07	-0.07	0.01	0.99	FALSE
2	GTEx	Artery Coronary	STAG3L2	0.16	0.10	lasso	3	0.11	1.5e-04	5.4	-5.2	1.8e-07	-0.07	0.01	0.93	FALSE
8	GTEx	Testis	STAG3L2	0.26	0.13	lasso	4	0.22	4.0e-10	5.0	-5.2	1.8e-07	-0.08	0.02	0.98	FALSE
3	GTEx	Breast Mammary Tissue	STAG3L2	0.14	0.08	lasso	2	0.11	4.0e-06	5.4	-5.2	1.9e-07	-0.07	0.01	0.99	FALSE
5	GTEx	Esophagus Mucosa	STAG3L2	0.23	0.16	lasso	3	0.16	1.0e-10	5.4	-5.2	2.1e-07	-0.08	0.01	0.99	FALSE