Best TWAS P=5.67e-13 · Best GWAS P=4.65e-09 conditioned to 0.175
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | JHDM1D | 0.14 | 0.07 | bslmm | 490 | 0.12 | 3.6e-15 | 2.2 | -6.1 | 1.4e-09 | -0.67 | 0.03 | 0.97 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | JHDM1D | 0.14 | 0.01 | blup | 58 | 0.04 | 6.2e-05 | 5.9 | -7.2 | 5.7e-13 | -0.67 | 0.01 | 0.85 | TRUE |