TWAS
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Traits
:
Lung FEV1/FVC ratio
:
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→
chr8:130,160,834-131,728,731
Best TWAS P=5.29e-08 · Best GWAS P=5.7e-09 conditioned to 0.000295
130.2M
130.4M
130.6M
130.8M
131M
131.2M
131.4M
131.6M
131.8M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
FAM49B
0.09
0.01
enet
17
0.01
0.063
3
5.4
5.3e-08
-0.49
0.08
0.71
TRUE