[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr10:32,035,353-33,875,979

Best TWAS P=7.82e-09 · Best GWAS P=4.43e-11 conditioned to 0.00054

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-479G22.8 0.14 0.18 lasso 4 0.18 1.1e-14 4.7 -5.1 3.1e-07 -0.43 0.24 0.75 FALSE
2 GTEx Adrenal Gland RP11-479G22.8 0.23 0.21 lasso 11 0.19 2.8e-07 4.7 -5.2 2.1e-07 -0.47 0.19 0.79 FALSE
3 GTEx Artery Aorta CCDC7 0.10 0.02 enet 11 0.05 1.1e-03 4.9 5.2 2.6e-07 0.67 0.67 0.06 FALSE
4 GTEx Artery Tibial CCDC7 0.06 0.01 enet 31 0.03 1.5e-03 4.7 5.6 1.8e-08 0.59 0.55 0.28 FALSE
5 GTEx Brain Caudate basal ganglia RP11-479G22.8 0.11 0.06 lasso 3 0.04 2.8e-02 5.1 -5.2 1.5e-07 -0.51 0.05 0.50 FALSE
6 GTEx Brain Cerebellum CCDC7 0.30 0.08 enet 31 0.19 2.1e-06 5.0 5.6 2.6e-08 0.69 0.59 0.29 FALSE
7 GTEx Breast Mammary Tissue RP11-479G22.8 0.15 0.05 enet 23 0.14 2.0e-07 4.6 -5.5 3.2e-08 -0.54 0.10 0.89 FALSE
8 GTEx Pituitary RP11-479G22.8 0.32 0.30 enet 21 0.32 1.0e-08 4.7 -5.8 8.8e-09 -0.53 0.23 0.72 FALSE
9 GTEx Spleen RP11-479G22.8 0.15 0.20 lasso 4 0.15 9.9e-05 5.1 -5.3 9.4e-08 -0.56 0.07 0.70 FALSE
10 GTEx Whole Blood CCDC7 0.06 0.00 lasso 11 0.01 1.8e-02 4.2 5.8 7.8e-09 0.74 0.08 0.83 TRUE