[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr10:32,035,353-33,875,979

Best TWAS P=7.82e-09 · Best GWAS P=4.43e-11 conditioned to 0.00054

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	GTEx	Whole Blood	CCDC7	0.06	0.00	lasso	11	0.01	1.8e-02	4.2	5.8	7.8e-09	0.74	0.08	0.83	TRUE
8	GTEx	Pituitary	RP11-479G22.8	0.32	0.30	enet	21	0.32	1.0e-08	4.7	-5.8	8.8e-09	-0.53	0.23	0.72	FALSE
4	GTEx	Artery Tibial	CCDC7	0.06	0.01	enet	31	0.03	1.5e-03	4.7	5.6	1.8e-08	0.59	0.55	0.28	FALSE
6	GTEx	Brain Cerebellum	CCDC7	0.30	0.08	enet	31	0.19	2.1e-06	5.0	5.6	2.6e-08	0.69	0.59	0.29	FALSE
7	GTEx	Breast Mammary Tissue	RP11-479G22.8	0.15	0.05	enet	23	0.14	2.0e-07	4.6	-5.5	3.2e-08	-0.54	0.10	0.89	FALSE
9	GTEx	Spleen	RP11-479G22.8	0.15	0.20	lasso	4	0.15	9.9e-05	5.1	-5.3	9.4e-08	-0.56	0.07	0.70	FALSE
5	GTEx	Brain Caudate basal ganglia	RP11-479G22.8	0.11	0.06	lasso	3	0.04	2.8e-02	5.1	-5.2	1.5e-07	-0.51	0.05	0.50	FALSE
2	GTEx	Adrenal Gland	RP11-479G22.8	0.23	0.21	lasso	11	0.19	2.8e-07	4.7	-5.2	2.1e-07	-0.47	0.19	0.79	FALSE
3	GTEx	Artery Aorta	CCDC7	0.10	0.02	enet	11	0.05	1.1e-03	4.9	5.2	2.6e-07	0.67	0.67	0.06	FALSE
1	GTEx	Adipose Subcutaneous	RP11-479G22.8	0.14	0.18	lasso	4	0.18	1.1e-14	4.7	-5.1	3.1e-07	-0.43	0.24	0.75	FALSE