[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr10:30,411,253-32,016,090

Best TWAS P=1.49e-13 · Best GWAS P=4.11e-14 conditioned to 0.333

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Esophagus Muscularis	ZNF438	0.08	0.07	enet	9	0.07	4.7e-05	-7.4	-7.4	1.5e-13	0.89	0.01	0.99	TRUE
6	The Cancer Genome Atlas	Lung Adenocarcinoma	ZNF438	0.07	0.03	lasso	5	0.04	1.9e-05	6.0	5.3	1.1e-07	-0.26	0.90	0.02	TRUE
5	GTEx	Testis	ZNF438	0.23	0.21	enet	20	0.23	1.9e-10	5.8	-6.7	3.0e-11	0.76	0.12	0.87	FALSE
4	GTEx	Pituitary	ZNF438	0.29	0.01	enet	17	0.03	5.2e-02	5.3	6.1	1.3e-09	-0.48	0.07	0.18	FALSE
1	GTEx	Artery Aorta	ZNF438	0.12	0.00	enet	10	0.03	1.3e-02	-6.7	-6.0	1.6e-09	0.83	0.05	0.80	FALSE
2	GTEx	Artery Tibial	ZNF438	0.14	0.03	lasso	9	0.08	6.1e-07	2.6	-5.8	8.8e-09	0.73	0.12	0.83	FALSE
7	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ZNF438	0.07	0.01	blup	123	0.03	1.9e-02	2.8	-5.1	3.1e-07	0.74	0.04	0.39	FALSE