Best TWAS P=9.4e-10 · Best GWAS P=4.22e-09 conditioned to 0.0071
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | GANAB | 0.21 | 0.14 | lasso | 4 | 0.14 | 1.8e-10 | -5.8 | 6.0 | 2.7e-09 | -0.71 | 0.00 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | EML3 | 0.04 | 0.05 | blup | 27 | 0.05 | 3.5e-06 | 4.0 | 5.5 | 4.9e-08 | -0.42 | 0.68 | 0.23 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | EEF1G | 0.08 | 0.00 | blup | 27 | 0.04 | 1.3e-02 | 4.3 | -5.5 | 4.9e-08 | 0.48 | 0.05 | 0.40 | FALSE |
| 4 | The Cancer Genome Atlas | Rectum Adenocarcinoma | EML3 | 0.36 | 0.08 | blup | 27 | 0.19 | 3.7e-05 | 4.0 | 6.1 | 9.4e-10 | -0.61 | 0.02 | 0.67 | TRUE |