TWAS
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Traits
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Lung FEV1/FVC ratio
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chr11:120,623,637-122,199,441
Best TWAS P=6.86e-10 · Best GWAS P=9.9e-14 conditioned to 2.38e-07
120.6M
120.8M
121M
121.2M
121.4M
121.6M
121.8M
122M
122.2M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Cerebellar Hemisphere
SORL1
0.37
-0.01
lasso
10
0
0.29
-2.2
6.2
6.9e-10
0.46
0.06
0.27
TRUE