TWAS
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Lung FEV1/FVC ratio
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chr13:47,958,937-49,351,645
Best TWAS P=4e-08 · Best GWAS P=6.78e-07 conditioned to 0.576
48M
48.2M
48.4M
48.6M
48.8M
49M
49.2M
49.4M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Frontal Cortex BA9
MED4-AS1
0.42
0.01
enet
16
0.08
0.00451
-4.9
5.5
4.0e-08
-0.69
0.01
0.55
TRUE
2
GTEx
Nerve Tibial
MED4-AS1
0.08
0.01
enet
24
0.05
0.00033
-3.2
5.4
5.2e-08
-0.51
0.07
0.53
TRUE