Best TWAS P=4.78e-13 · Best GWAS P=1.58e-15 conditioned to 0.000263
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | KPNA3 | 0.04 | 0.02 | bslmm | 427 | 0.02 | 1.4e-08 | 7.8 | 6.0 | 1.6e-09 | 0.8 | 0.01 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | KPNA3 | 0.05 | 0.02 | blup | 75 | 0.04 | 4.6e-05 | -5.5 | -7.2 | 4.8e-13 | -0.8 | 0.02 | 0.96 | TRUE |