TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Lung FEV1/FVC ratio
:
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chr19:1,086,043-2,560,423
Best TWAS P=4.95e-09 · Best GWAS P=8.74e-11 conditioned to 0.00503
1M
1.2M
1.4M
1.6M
1.8M
2M
2.2M
2.4M
2.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Muscularis
KLF16
0.17
0.07
enet
9
0.09
3.7e-06
5.2
5.8
4.9e-09
0.90
0.00
0.99
TRUE
3
GTEx
Esophagus Muscularis
CTB-31O20.6
0.16
0.07
lasso
5
0.05
7.8e-04
5.2
5.4
6.3e-08
0.88
0.01
0.98
FALSE
2
GTEx
Esophagus Muscularis
ATP8B3
0.33
0.23
enet
31
0.25
2.1e-15
5.2
5.2
2.5e-07
0.73
0.76
0.24
FALSE