TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Lung FEV1/FVC ratio
:
←
→
chr18:19,692,435-21,303,692
Best TWAS P=2.42e-08 · Best GWAS P=2.11e-19 conditioned to 7.2e-15
19.6M
19.8M
20M
20.2M
20.4M
20.6M
20.8M
21M
21.2M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Cerebellar Hemisphere
RBBP8
0.22
0.16
enet
20
0.13
3e-04
2.4
-5.6
2.4e-08
-0.27
0.12
0.35
TRUE