Best TWAS P=2.15e-25 · Best GWAS P=9.13e-47 conditioned to 9.1e-26
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | KCNS3 | 0.20 | 0.06 | enet | 20 | 0.08 | 1.0e-05 | 7.8 | 10.4 | 2.1e-25 | 0.52 | 0.13 | 0.79 | TRUE |
| 2 | GTEx | Pancreas | KCNS3 | 0.47 | 0.18 | enet | 41 | 0.28 | 2.5e-12 | -1.2 | 6.2 | 4.9e-10 | 0.27 | 0.84 | 0.13 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | KCNS3 | 0.09 | 0.06 | lasso | 7 | 0.05 | 1.3e-06 | 6.7 | 6.3 | 2.2e-10 | 0.38 | 1.00 | 0.00 | FALSE |