TWAS
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Traits
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Traits
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Lung FEV1/FVC ratio
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chr1:18,940,380-20,503,710
Best TWAS P=2.89e-11 · Best GWAS P=1.84e-17 conditioned to 1.08e-07
19M
19.2M
19.4M
19.6M
19.8M
20M
20.2M
20.4M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Testis
CAPZB
0.28
0.09
enet
18
0.09
7.8e-05
-5.9
-6.7
2.9e-11
0.75
0.13
0.79
TRUE
1
GTEx
Testis
PQLC2
0.23
0.14
lasso
7
0.09
1.1e-04
-5.9
-5.8
8.1e-09
0.78
0.51
0.24
FALSE