TWAS
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About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Lung FEV1/FVC ratio
:
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chr4:703,813-1,215,100
Best TWAS P=2.9e-09 · Best GWAS P=5.55e-06 conditioned to 0.186
0.7M
0.8M
0.9M
1M
1.1M
1.2M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
DGKQ
0.08
0.05
blup
50
0.07
6.9e-08
-4.4
-5.9
2.9e-09
-0.58
0.01
0.89
TRUE