TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Lung FEV1/FVC ratio
:
←
→
chr6:17,060,849-18,686,970
Best TWAS P=4.99e-10 · Best GWAS P=3.23e-11 conditioned to 0.327
17M
17.2M
17.4M
17.6M
17.8M
18M
18.2M
18.4M
18.6M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Thyroid Carcinoma
KIF13A
0.15
0.04
lasso
3
0.05
4.6e-06
4.2
6.2
5.0e-10
-0.27
0.29
0.37
TRUE
1
GTEx
Artery Tibial
KIF13A
0.20
0.10
lasso
7
0.08
3.5e-07
-5.5
-5.3
1.2e-07
0.86
0.19
0.81
TRUE