Best TWAS P=4.99e-10 · Best GWAS P=3.23e-11 conditioned to 0.327
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | KIF13A | 0.20 | 0.10 | lasso | 7 | 0.08 | 3.5e-07 | -5.5 | -5.3 | 1.2e-07 | 0.86 | 0.19 | 0.81 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | KIF13A | 0.15 | 0.04 | lasso | 3 | 0.05 | 4.6e-06 | 4.2 | 6.2 | 5.0e-10 | -0.27 | 0.29 | 0.37 | TRUE |