Best TWAS P=1.46e-27 · Best GWAS P=1.7e-49 conditioned to 6.77e-50
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hippocampus | RIOK1 | 0.39 | -0.01 | enet | 47 | 0.01 | 1.9e-01 | -5.9 | -6.6 | 4.6e-11 | -0.01 | 0.08 | 0.09 | TRUE |
| 2 | GTEx | Lung | DSP | 0.33 | 0.23 | lasso | 4 | 0.23 | 1.9e-17 | 10.8 | -10.9 | 1.5e-27 | -0.02 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | EEF1E1 | 0.06 | 0.03 | blup | 65 | 0.04 | 1.0e-05 | -5.7 | 6.3 | 3.7e-10 | -0.04 | 0.05 | 0.95 | TRUE |