[Hub]/) : Traits : Lung FVC : ← →

chr7:5,925,156-7,988,091

Best TWAS P=9.42e-09 · Best GWAS P=4.35e-08 conditioned to 5.99e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts ZDHHC4 0.25 0.10 enet 25 0.11 1.3e-08 -4.1 5.7 1.1e-08 0.29 0.37 0.51 FALSE
2 GTEx Cells Transformed fibroblasts AC079742.4 0.19 0.08 enet 26 0.06 1.9e-05 -4.1 5.7 9.4e-09 0.20 0.23 0.31 TRUE
3 GTEx Skin Sun Exposed Lower leg C1GALT1 0.22 0.04 lasso 9 0.10 4.8e-09 -3.9 -5.2 2.3e-07 0.03 0.60 0.29 FALSE
4 GTEx Spleen C1GALT1 0.56 0.29 lasso 6 0.46 3.2e-13 -3.8 -5.3 1.2e-07 -0.03 0.29 0.57 FALSE
5 ROSMAP Brain Pre-frontal Cortex C1GALT1 0.24 0.13 lasso 5 0.23 4.6e-29 3.5 -5.1 2.8e-07 -0.04 0.48 0.44 FALSE
6 YFS Blood C1GALT1 0.35 0.20 enet 45 0.32 4.3e-109 -4.4 -5.4 6.9e-08 -0.02 0.21 0.75 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma C1GALT1 0.08 0.03 blup 112 0.06 2.5e-07 4.8 -5.4 6.8e-08 -0.06 0.01 0.97 FALSE
8 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C1GALT1 0.04 0.00 blup 108 0.02 2.7e-03 1.7 -5.4 6.4e-08 -0.07 0.02 0.58 TRUE