Best TWAS P=2.12e-10 · Best GWAS P=7.65e-09 conditioned to 0.563
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | ZNF438 | 0.13 | 0.03 | enet | 21 | 0.06 | 1.4e-05 | -5.8 | 6.4 | 2.1e-10 | -0.86 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZNF438 | 0.03 | 0.00 | blup | 123 | 0.02 | 1.8e-05 | 2.9 | 5.4 | 5.6e-08 | -0.76 | 0.04 | 0.91 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZNF438 | 0.06 | 0.02 | lasso | 4 | 0.02 | 1.8e-03 | -4.0 | 5.3 | 1.5e-07 | -0.82 | 0.05 | 0.88 | FALSE |