TWAS hub - ZNF438

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0600	0.0220	4.1e-04	0.051	0.023	0.034	0.022	0.030	7.9e-07	7.5e-04	4.3e-05	8.7e-04	1.3e-04
2	GTEx	Artery Aorta	0.1240	0.0510	6.3e-03	-0.004	NA	0.027	NA	0.008	6.9e-01	NA	1.3e-02	NA	1.1e-01
3	GTEx	Artery Tibial	0.1363	0.0423	1.5e-05	0.031	NA	0.065	NA	0.081	1.6e-03	NA	8.0e-06	NA	6.1e-07
4	GTEx	Esophagus Muscularis	0.0850	0.0300	6.5e-04	0.070	NA	0.070	NA	0.063	4.4e-05	NA	4.7e-05	NA	1.1e-04
5	GTEx	Pituitary	0.2890	0.1090	7.6e-03	0.010	NA	0.033	NA	0.016	1.7e-01	NA	5.2e-02	NA	1.3e-01
6	GTEx	Testis	0.2300	0.0630	1.1e-06	0.211	NA	0.227	NA	0.205	1.0e-09	NA	1.9e-10	NA	1.8e-09
7	GTEx	Thyroid	0.1330	0.0410	6.0e-05	0.033	NA	0.063	NA	0.043	1.4e-03	NA	1.4e-05	NA	2.8e-04
8	GTEx	Whole Blood	0.0750	0.0320	1.6e-03	0.003	NA	-0.003	NA	-0.003	1.6e-01	NA	7.5e-01	NA	8.8e-01
9	ROSMAP	Brain Pre-frontal Cortex	0.1134	0.0323	1.2e-07	0.051	0.061	0.043	0.064	0.068	3.7e-07	2.9e-08	2.8e-06	1.3e-08	4.6e-09
10	YFS	Blood	0.0202	0.0076	1.1e-03	0.003	0.008	0.004	0.009	0.004	2.6e-02	9.8e-04	1.2e-02	3.4e-04	2.0e-02
11	TCGA	Breast Invasive Carcinoma	0.0295	0.0126	2.1e-05	0.001	0.022	0.015	NA	0.010	1.5e-01	1.8e-05	4.0e-04	NA	3.1e-03
12	TCGA	Glioblastoma Multiforme	0.2040	0.1010	4.6e-03	0.125	0.088	0.063	NA	0.079	1.3e-04	1.3e-03	5.5e-03	NA	2.2e-03
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0961	0.0368	6.2e-06	0.038	0.035	0.024	NA	0.036	4.1e-05	6.8e-05	9.3e-04	NA	5.9e-05
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.0423	0.0227	1.7e-03	0.021	0.021	0.020	NA	0.025	1.8e-03	1.7e-03	2.2e-03	NA	6.8e-04
15	TCGA	Brain Lower Grade Glioma	0.0948	0.0383	1.8e-06	0.030	0.034	0.035	NA	0.032	2.2e-04	8.1e-05	7.1e-05	NA	1.4e-04
16	TCGA	Lung Adenocarcinoma	0.0735	0.0292	5.2e-06	0.029	0.028	0.031	NA	0.039	2.0e-04	2.6e-04	1.3e-04	NA	1.9e-05
17	TCGA	Pheochromocytoma and Paraganglioma	0.0690	0.0400	9.5e-03	0.014	0.033	0.024	NA	0.029	8.5e-02	1.9e-02	3.7e-02	NA	2.4e-02
18	TCGA	Prostate Adenocarcinoma	0.0563	0.0292	5.5e-04	0.022	0.021	0.017	NA	0.023	1.9e-03	2.4e-03	5.8e-03	NA	1.8e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	9	10	11	12	13	14	15	16	17	18
Forced vital capacity (FVC), Best measure	5.0	18.4	31.9	5.2	2.3	3.4	3.3	2.5	2.2	4.9	4.0	-4.6	5.5	5.1	4.7	5.6	5.2	4.5	4.7	5.2
Forced expiratory volume in 1-second (FEV1), Best measure	4.8	15.4	32.3	4.0	0.2	1.2	1.1	3.9	0.0	3.7	2.8	-5.2	5.7	4.5	5.6	4.6	5.7	5.7	2.8	4.0
Forced vital capacity (FVC)	4.2	16.0	27.5	4.7	2.1	2.5	3.2	2.5	1.9	5.0	4.0	-4.7	5.2	4.6	4.0	5.1	4.8	3.6	4.4	5.0
Forced expiratory volume in 1-second (FEV1)	4.0	13.4	29.5	3.6	-0.0	0.4	0.8	3.9	-0.3	3.7	2.6	-5.2	5.4	4.1	5.1	4.0	5.3	4.9	2.5	4.0
Lung FEV1/FVC ratio	3.7	18.8	54.6	-2.5	-6.0	-5.8	-7.4	6.1	-6.7	-3.5	-3.1	-3.0	2.1	-0.6	4.0	-2.6	3.1	5.3	-5.1	-1.7
Father’s age at death	3.3	4.4	12.5	-3.1	-1.8	-2.9	-2.6	1.9	-3.5	-1.7	-2.7	-0.3	-1.6	-1.2	-0.9	-2.6	-1.7	-0.1	-2.5	-2.0
Supplements: Glucosamine	3.2	4.2	8.3	2.9	0.7	2.9	1.6	0.6	1.0	1.8	2.4	-0.2	2.9	2.0	2.1	2.6	2.7	1.9	1.9	2.6
Relative age voice broke	3.1	4.7	13.0	2.5	3.2	2.7	3.1	-0.5	3.4	1.9	2.2	-1.4	1.4	1.9	0.4	2.5	0.7	0.2	3.6	2.0
Heel bone mineral density (BMD) T-score, automated (right)	3.1	7.0	27.2	2.3	-3.8	-2.2	-3.0	1.8	-3.6	1.7	3.1	-0.4	5.2	0.4	2.4	-0.8	4.1	2.8	-1.2	1.9
Number of full sisters	3.1	3.7	9.3	2.4	0.6	2.3	1.7	0.8	1.4	2.4	1.4	-1.4	2.5	1.9	1.7	2.6	1.9	1.3	2.5	3.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.1	6.5	14.4	3.0	2.3	2.6	2.0	1.2	1.6	3.2	2.1	-2.5	2.8	3.8	2.5	3.3	2.5	1.4	3.4	2.9
Lung FVC	3.0	15.5	40.4	4.9	1.7	3.7	3.5	1.2	2.3	6.4	4.6	-3.0	5.4	5.0	2.9	4.5	4.2	1.4	4.2	5.3
Qualifications: CSEs or equivalent	3.0	3.9	9.9	-1.3	-3.1	-2.7	-3.1	2.7	-2.7	-0.5	-1.5	-2.3	1.6	-0.0	2.0	-0.9	1.6	2.0	-2.0	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	2.9	6.5	24.4	2.1	-3.9	-1.9	-3.1	1.8	-3.3	1.1	2.6	-0.3	4.9	0.8	2.5	-0.5	4.1	3.0	-1.2	2.2
Rheumatoid Arthritis	2.8	3.8	16.7	1.9	2.7	2.2	4.1	-0.2	3.0	1.7	0.9	-0.9	-0.5	1.0	0.2	3.2	-0.3	0.2	2.8	1.9
Average weekly champagne plus white wine intake	2.8	3.8	13.3	-3.6	0.4	-2.0	-0.2	-1.1	-0.2	0.2	-1.9	-0.2	-2.3	-2.1	-3.1	-2.5	-3.6	-1.9	-1.0	-1.9
Ever used hormone-replacement therapy (HRT)	2.7	3.5	11.7	-1.9	0.4	-0.8	0.4	-1.4	-0.3	-1.8	-1.6	1.7	-3.4	-1.9	-2.6	-1.8	-2.9	-2.3	-1.2	-2.6
Alcohol usually taken with meals	2.7	4.4	8.9	-3.0	-0.7	-2.2	-1.7	-0.8	-1.3	-3.0	-2.9	1.1	-3.0	-2.0	-1.5	-2.5	-2.5	-1.1	-2.5	-2.5
Qualifications: None of the above	2.6	5.6	13.8	3.5	0.3	1.7	1.4	2.4	1.9	1.9	2.9	-1.5	3.0	1.5	2.6	2.8	3.7	2.6	2.0	3.1
Commuting to job workplace: Cycle	2.6	3.1	7.9	1.2	2.8	2.5	2.5	-1.4	2.4	2.1	1.1	0.5	-0.2	0.9	-2.0	0.8	-0.9	-2.6	2.4	1.0
Leg pain on walking	2.4	3.0	11.8	2.8	-0.9	0.1	1.3	0.7	2.3	2.2	3.4	-0.8	2.7	-0.1	0.8	1.2	2.3	0.7	0.9	2.2
Medication: Lisinopril	2.4	3.1	8.0	1.1	-0.4	0.6	-0.5	2.7	-0.7	1.3	-0.1	-2.8	2.2	1.8	2.8	2.4	2.2	2.7	0.7	1.6
Ever depressed for a whole week	2.4	3.0	8.0	-2.4	-2.3	-2.5	-2.8	2.0	-2.3	-1.4	-2.5	-0.6	-0.1	-1.1	0.6	-1.3	-0.0	1.3	-2.4	-1.0
Ovarian Cancer	2.3	3.1	8.6	-0.4	2.7	1.8	2.5	-1.9	2.9	1.2	-0.4	-0.5	-1.3	0.2	-2.3	0.6	-2.3	-2.7	2.0	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.3	2.7	8.1	-0.8	-2.1	-2.3	-2.4	2.9	-2.8	-0.7	-0.2	-0.6	1.3	-0.4	0.9	-1.5	1.5	2.0	-2.0	-0.9
Heel T-Score	2.2	17.6	66.9	2.7	-6.7	-3.8	-5.0	1.0	-7.2	2.8	4.4	1.9	8.2	0.1	2.1	-2.6	5.4	4.0	-2.4	3.6
Medication for hormone replacement therapy	2.2	2.5	6.2	-2.4	-0.0	-1.1	-0.1	-0.5	-0.1	-1.7	-1.8	0.8	-2.4	-1.4	-2.5	-2.0	-2.5	-1.8	-0.9	-1.9
Blood clot in the leg (DVT)	2.2	2.9	9.1	2.5	1.4	2.1	1.1	-0.2	-0.0	1.1	1.3	-0.9	1.6	3.0	1.9	2.0	2.1	1.1	2.2	2.0
Respiratory disease	2.1	4.7	22.6	1.2	3.2	2.3	4.0	-0.6	4.8	1.4	0.7	-0.9	-0.1	0.8	-1.4	2.6	-0.7	-1.5	3.3	1.4
Medication: Aspirin	2.1	2.8	8.5	2.0	1.0	1.3	0.5	0.7	0.2	0.8	0.1	-1.4	2.1	1.8	2.3	2.5	2.5	2.9	1.5	2.0
Supplements: Fish oil (including cod liver oil)	2.1	2.7	8.0	2.2	1.4	2.8	2.4	-0.9	1.7	1.0	1.8	0.4	1.2	2.2	0.7	1.7	1.4	0.2	2.7	1.3
Deep venous thrombosis (DVT) (self-reported)	2.1	2.7	9.1	2.4	1.5	1.8	1.1	-0.1	0.1	0.8	1.2	-1.1	1.5	3.0	2.0	2.0	2.1	1.2	2.2	1.8
Tinnitus: Yes, but not now, but have in the past	2.0	2.1	4.5	2.0	-0.1	1.7	1.3	1.1	0.3	1.3	1.9	-1.6	2.1	0.9	1.0	1.5	1.8	1.1	1.7	2.1
Mouth/teeth dental problems	2.0	3.0	8.9	-3.0	-1.9	-2.7	-2.2	0.3	-1.9	-0.7	-2.3	0.2	-1.2	-1.0	-0.8	-2.0	-1.8	-0.7	-2.5	-1.8
Guilty feelings	2.0	3.1	8.2	1.9	0.7	1.6	2.4	0.3	1.9	2.9	1.7	-1.4	1.8	0.8	0.6	2.8	1.5	0.3	2.1	2.7
Chronotype (morning person)	1.9	4.4	11.8	2.1	1.5	1.0	1.8	0.9	0.8	2.3	1.4	-2.1	2.8	2.5	2.0	2.6	2.3	2.5	2.7	3.4
Medication: Ibuprofen	1.9	2.3	5.5	-1.9	-2.2	-2.4	-2.1	0.0	-1.1	-0.6	-0.9	1.4	-0.7	-1.5	-1.0	-2.2	-0.8	-1.3	-2.3	-1.6
Friendships satisfaction	1.9	2.4	7.5	2.4	-0.8	0.7	0.7	0.5	0.4	2.0	2.3	-0.9	2.7	0.1	1.1	1.4	2.5	1.2	0.7	2.3
Asthma (self-reported)	1.9	3.7	16.3	1.4	2.3	2.3	3.7	-1.0	4.0	1.4	1.1	-0.7	0.3	0.5	-1.2	2.1	-0.6	-1.9	2.9	1.2
Medication: Aspirin	1.9	2.5	5.9	2.0	1.2	1.4	0.8	0.0	0.4	1.3	0.5	-1.1	2.1	1.8	1.9	2.2	2.1	2.4	1.8	1.9
Alcohol intake versus 10 years previously	1.8	2.7	8.1	2.3	1.6	2.0	2.8	-0.6	1.5	1.5	1.9	-1.1	1.3	1.4	1.5	2.9	1.2	0.6	2.1	0.9
Smoking status: Previous	1.8	2.7	8.7	0.8	-0.6	-0.4	-0.7	2.5	-1.8	0.5	-0.1	-2.4	1.9	2.2	3.0	1.2	2.3	2.7	-0.1	0.4
Average weekly red wine intake	1.8	2.7	5.9	-1.9	0.1	-0.8	-0.6	-1.3	0.3	-1.9	-0.7	2.0	-2.1	-1.7	-2.4	-2.4	-2.4	-2.2	-1.0	-1.8
Basal cell carcinoma (self-reported)	1.8	2.1	7.0	0.1	-0.6	-0.2	-2.0	1.9	-2.2	-2.2	-0.9	-0.7	-0.1	0.6	2.6	0.1	1.5	2.3	-1.5	-1.2
Worrier / anxious feelings	1.7	3.2	9.2	2.2	0.7	1.5	2.0	-0.2	1.9	2.6	2.5	-1.2	2.3	0.4	0.3	2.1	1.6	0.6	2.2	3.0
Breast cancer (self-reported)	1.7	2.0	7.9	2.8	0.1	1.9	0.7	-1.2	0.2	2.2	2.6	1.0	1.4	1.0	0.6	0.8	1.4	-0.2	1.1	1.5
Miserableness	1.7	2.9	7.0	2.0	0.6	2.2	1.5	0.5	1.9	2.6	2.3	-1.3	2.1	0.8	1.0	1.6	1.6	0.6	2.1	2.6
Diastolic blood pressure, automated reading	1.7	5.2	19.8	2.6	-1.1	-0.0	-0.6	3.7	-1.6	0.4	1.2	-1.1	2.5	2.7	4.5	2.2	4.3	3.0	-0.2	0.8
Hearing difficulty/problems: Yes	1.6	2.5	7.2	-2.0	0.7	-0.3	-1.0	-1.7	-1.3	-2.1	-2.5	1.8	-2.7	-0.4	-1.4	-1.5	-2.1	-1.2	-0.8	-1.5
Severe depression (siblings)	1.6	1.8	6.9	-0.4	-0.7	-0.5	-1.5	2.3	-2.0	-0.8	-1.4	-1.4	1.0	1.3	1.8	0.0	1.7	2.6	-0.3	-0.4
Qualifications: A levels/AS levels or equivalent	1.6	3.5	8.9	-2.5	-1.0	-1.9	-0.6	-1.2	-0.0	-1.0	-1.8	1.4	-2.1	-2.9	-2.9	-2.0	-3.0	-1.9	-1.6	-1.8
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.1	5.3	-2.1	-2.1	-2.3	-2.2	0.2	-1.0	-1.0	-1.4	0.9	-0.4	-1.4	-0.9	-1.9	-0.5	-1.0	-2.1	-1.0
Length of working week for main job	1.6	1.8	4.6	1.6	1.3	1.0	1.5	0.8	0.4	1.3	1.0	-1.7	0.9	2.2	1.4	1.9	1.3	0.7	1.9	1.3
Ever highly irritable/argumentative for 2 days	1.6	2.0	4.7	1.5	1.1	1.5	1.0	0.7	0.8	1.0	0.9	-1.7	1.4	1.5	1.6	2.2	2.0	1.6	1.5	1.6
Illnesses of siblings: Diabetes	1.6	2.0	6.5	1.5	0.0	0.5	-0.7	1.2	-0.6	0.7	0.5	-1.4	2.2	2.2	2.5	1.1	2.4	2.0	0.6	0.7
Hearing aid user	1.6	1.9	6.0	-1.4	1.4	0.4	0.6	-1.6	0.7	0.0	-1.1	1.2	-2.4	-1.0	-1.7	-0.8	-2.5	-2.4	0.1	-0.9
Fractured/broken bones in last 5 years	1.6	2.0	7.8	0.5	2.8	1.7	2.3	-0.6	2.3	1.6	1.3	-0.8	0.0	0.7	-1.2	0.6	-0.6	-1.2	2.2	1.0
Supplements: Calcium	1.6	1.8	4.6	0.7	0.6	2.1	2.1	-1.2	1.9	1.9	1.9	0.6	0.0	-0.6	-1.7	-0.1	-0.9	-1.6	1.5	0.8
Intelligence (Savage-Jansen 2018)	1.5	4.6	14.4	-0.2	3.5	2.0	3.0	-3.8	3.1	0.7	0.5	0.3	-2.0	0.1	-2.4	0.8	-2.7	-3.3	1.9	0.7
Verbal and Numeric Reasoning (VNR)	1.5	3.5	16.9	-0.5	1.3	1.4	1.9	-3.0	2.7	0.9	0.8	1.0	-1.5	-0.8	-3.0	-0.4	-2.6	-4.1	0.8	0.7
Waist Hip Ratio (WHR)	1.5	6.6	19.5	4.4	1.3	3.0	2.2	-0.5	2.5	3.2	3.5	-0.3	2.7	2.5	1.6	3.4	3.2	0.8	2.9	2.9
Asthma	1.5	3.1	12.8	1.3	2.0	2.1	3.3	-0.8	3.6	1.1	1.1	-0.7	0.4	0.4	-1.1	1.9	-0.5	-1.7	2.7	1.3
Mineral and other dietary supplements	1.5	2.0	7.0	-1.7	-0.6	-2.6	-1.9	0.6	-1.4	-1.3	-2.0	-0.5	-1.6	-1.3	-0.4	-1.4	-1.1	-0.1	-2.0	-1.6
Average weekly spirits intake	1.4	1.7	4.3	1.4	1.2	0.9	1.0	0.9	0.9	0.4	0.0	-1.4	1.0	1.6	1.8	2.1	1.2	1.8	1.6	2.0
Frequency of depressed mood in last 2 weeks	1.4	1.9	4.3	1.9	0.9	2.1	1.7	1.1	1.7	1.3	1.7	-0.6	1.3	0.7	0.8	2.0	1.8	0.5	1.5	1.4
Past tobacco smoking	1.4	2.5	9.6	-0.6	-0.0	0.3	-0.3	-2.1	1.0	-0.7	0.6	3.1	-1.6	-2.2	-2.4	-1.8	-1.8	-2.8	-0.6	-0.6
Commuting to job workplace: Car/motor vehicle	1.4	1.6	6.0	1.5	-1.1	0.7	-1.2	1.1	-0.0	0.3	1.7	-0.5	2.0	0.1	1.9	0.4	2.4	2.0	0.2	1.1
Back pain experienced in last month	1.4	2.0	9.0	1.1	-0.3	-0.8	1.3	1.0	1.8	3.0	2.3	-0.9	1.9	-0.1	-0.7	0.4	1.3	0.3	0.8	2.5
Osteoarthritis (self-reported)	1.4	1.8	5.2	2.0	0.4	0.3	1.4	0.9	1.3	2.3	1.8	-1.0	1.8	0.8	1.0	1.6	1.7	-0.1	1.3	1.6
Unable to work because of sickness or disability	1.4	1.9	5.0	1.6	0.9	1.7	0.6	1.1	0.9	0.5	0.5	-1.5	2.0	1.6	1.7	2.2	1.8	1.4	1.3	1.3
Neuroticism (Nagel 2018)	1.3	3.0	14.3	1.4	-0.3	1.6	1.8	-0.1	1.6	3.8	2.8	-0.6	2.6	-0.0	-0.3	1.2	1.0	-0.7	1.8	2.9
Worry (Nagel 2018)	1.3	2.7	14.6	1.0	-0.4	0.6	1.2	0.4	1.4	3.8	2.6	-1.3	2.9	0.1	-0.5	0.8	1.3	0.1	1.5	2.8
Breast Cancer	1.3	3.0	10.7	0.8	3.0	1.7	2.7	0.1	3.3	1.1	0.2	-2.2	-0.1	1.5	0.2	2.4	-0.1	0.4	2.9	1.2
Neuroticism (2016)	1.3	1.8	5.7	1.2	0.6	1.1	1.9	0.7	0.8	2.2	1.4	-1.6	1.6	0.6	0.4	1.8	0.8	0.3	1.7	2.4
Serious illness, injury or assault to yourself	1.3	1.5	4.7	1.2	-0.5	-0.1	1.3	-1.3	1.7	2.0	2.2	0.9	0.6	-0.9	-1.3	0.3	-0.7	-1.8	0.7	1.7
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	5.6	-1.2	-0.8	-0.7	-2.4	0.8	-1.5	-2.2	-2.2	-0.0	-0.1	0.3	1.4	-0.5	0.6	1.6	-1.2	-1.1
Coronary Artery Disease (CAD)	1.2	1.4	5.0	-0.0	2.2	-0.0	2.2	-1.2	2.1	1.3	-0.6	-1.0	-0.5	0.2	-0.7	1.5	-0.7	0.0	1.8	0.5
Crohns Disease (2012)	1.2	1.9	10.8	-1.5	-1.3	-1.4	-1.5	0.5	-3.3	-1.8	-2.1	0.3	-0.9	0.6	0.6	-1.2	-0.4	0.9	-1.2	-1.1
Ulcerative Colitis	1.2	1.8	9.7	-0.9	-2.7	-3.1	-1.5	0.5	-2.1	0.5	-0.9	-0.4	0.9	-0.3	0.2	-1.2	0.1	1.2	-1.5	-0.5
Smoking Status	1.2	2.8	14.6	0.5	-0.7	-0.5	-1.1	2.1	-1.4	0.5	-0.5	-2.2	2.0	1.8	2.6	1.4	2.4	3.8	0.1	1.1
Pain all over the body in last month	1.2	1.3	3.0	-1.3	-0.9	-0.3	-1.5	0.9	0.1	-1.6	-0.6	0.7	-1.0	-1.7	-1.0	-1.7	-0.7	-1.4	-1.4	-1.4
Number of live births	1.2	1.6	6.0	-0.8	-0.2	0.6	-0.2	-1.8	0.5	-0.9	0.3	2.5	-1.2	-1.7	-1.9	-1.4	-1.6	-2.2	-0.6	-0.7
Mouth/teeth dental problems: Dentures	1.2	2.0	7.5	2.1	2.7	2.3	2.3	-0.8	1.6	-0.5	1.2	0.4	-0.7	0.8	0.2	1.7	0.3	-0.0	2.0	0.3
Medication: Lansoprazole	1.2	1.3	5.7	0.4	0.2	0.2	-0.5	1.1	-1.2	0.2	-0.2	-1.2	1.5	1.5	1.9	1.1	1.8	2.4	0.6	1.1
Wheeze or whistling in the chest in last year	1.2	2.2	6.4	-0.3	1.1	1.0	2.5	-2.2	2.4	1.0	0.3	1.1	-1.3	-0.6	-2.5	0.2	-1.9	-2.1	1.1	0.3
Number of children fathered	1.2	1.3	5.3	-0.8	-1.7	-0.3	-1.9	0.6	-0.7	-1.1	0.7	1.1	-0.5	-1.7	-0.6	-2.3	-0.3	-0.0	-1.6	-1.1
Health satisfaction	1.2	1.5	4.6	0.7	-1.1	-0.2	0.7	-0.8	1.4	1.9	2.1	0.9	0.7	-2.0	-1.9	-0.7	-0.5	-1.6	-0.2	1.4
Migraine (self-reported)	1.2	1.5	4.3	-0.8	-2.1	-1.2	-1.6	1.0	-0.2	-1.5	-0.5	1.1	-0.7	-2.0	-0.9	-1.6	-0.2	-0.5	-1.8	-1.6
Ever had bowel cancer screening	1.2	1.5	5.3	-0.1	2.3	1.5	2.2	-1.2	1.6	0.8	0.5	-0.1	-0.7	0.2	-1.7	0.3	-1.0	-0.9	1.9	0.5
Pain type(s) experienced in last month: Hip pain	1.2	1.5	5.7	1.5	-1.8	0.1	0.3	0.9	0.9	0.9	2.4	0.1	2.1	-1.1	0.3	0.5	1.9	0.2	-0.1	2.0
Vascular/heart problems diagnosed by doctor	1.2	3.1	8.6	-2.6	-1.7	-1.7	-1.5	-0.6	-0.8	-1.7	-0.8	1.7	-1.7	-2.0	-2.2	-2.9	-2.2	-2.0	-1.7	-1.7
HbA1C	1.1	1.2	7.0	-1.2	-1.2	-2.6	-1.3	0.9	-1.4	0.0	-1.0	-1.4	0.5	-0.8	-0.5	-0.9	-0.1	0.5	-1.3	0.1
Angina	1.1	1.4	4.8	-0.1	1.9	1.2	2.2	-1.5	1.7	0.1	-1.0	0.6	-0.6	0.6	-1.6	1.1	-0.9	-0.8	1.7	1.0
Diabetes (self-reported)	1.1	1.7	7.9	1.5	-0.4	0.9	-0.9	1.6	-0.4	-0.2	1.0	-1.1	2.0	0.9	1.8	0.8	2.8	1.9	0.4	0.8
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	5.7	-2.1	-0.1	-0.9	-0.9	-0.7	-0.8	-1.5	-2.2	-0.0	-2.0	-0.7	-0.7	-1.0	-2.4	-1.1	-0.9	-1.8
Medication: Amlodipine	1.1	1.6	4.7	0.9	-1.2	-0.5	-1.9	1.4	-1.2	0.5	0.6	-1.6	1.8	0.4	1.7	0.3	2.2	1.8	-0.7	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	4.9	1.1	-0.0	1.3	1.4	1.3	1.6	2.2	1.8	-0.6	1.3	-0.4	-0.4	0.6	0.4	-0.0	1.2	1.9
Comparative height size at age 10	1.1	5.8	22.7	1.4	-0.9	-0.9	-0.3	4.5	-1.8	-0.6	0.5	-2.9	2.5	1.5	4.0	2.3	3.6	4.8	-0.0	1.6
Overall health rating	1.1	2.4	6.5	2.5	0.4	0.8	1.4	0.3	2.5	1.7	1.9	-0.3	1.9	0.3	0.9	2.1	1.9	0.3	1.4	2.4
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	8.7	1.2	-0.1	-0.3	1.0	1.4	0.6	1.2	0.8	-2.2	2.4	1.0	1.7	1.9	2.1	3.0	1.4	1.3
Diabetes diagnosed by doctor	1.1	1.8	7.9	1.4	-0.8	0.6	-0.9	1.8	-0.5	0.2	1.3	-1.0	2.5	0.6	1.5	0.6	2.8	2.1	0.2	1.2
Qualifications: nursing, teaching	1.1	1.8	5.1	-1.8	-1.1	-2.0	-1.2	-0.2	-1.5	0.5	-0.4	0.9	-0.1	-1.2	-2.0	-2.3	-1.6	-2.1	-1.2	-0.7
Illnesses of father: None of the above (group 1)	1.1	1.4	4.6	-0.9	-0.1	-0.4	0.1	-1.2	0.2	-1.4	-0.6	2.1	-2.0	-1.4	-1.5	-0.9	-1.5	-0.8	-1.2	-1.5
Risk taking	1.1	1.6	7.4	-1.5	1.2	-0.1	-0.8	0.1	-1.3	-2.4	-2.7	0.6	-2.0	0.5	0.2	-0.3	-1.2	0.1	-0.7	-1.9
Age started oral contraceptive pill	1.1	1.4	4.5	-1.4	-1.6	-1.5	-0.2	0.4	-0.7	-0.5	-0.1	0.2	-0.4	-2.1	-1.9	-1.6	-1.4	-1.6	-1.2	-0.9
Reaction Time	1.0	1.9	6.4	1.1	-0.6	1.6	-0.2	2.2	-0.1	0.2	1.1	-1.1	2.2	0.4	1.8	1.2	2.5	2.3	0.7	0.8
Age at First Birth	1.0	1.4	6.2	-0.9	0.7	0.4	1.2	-1.3	1.3	-0.2	0.1	1.3	-1.2	-1.2	-2.5	-1.0	-2.0	-1.7	0.5	-0.4
Bipolar Disorder (2011)	1.0	1.0	2.5	-0.9	-1.1	-1.1	-1.3	-0.1	-1.1	-1.3	-0.4	1.3	-1.0	-0.3	-0.4	-1.6	-0.6	-0.9	-1.2	-1.4
LDL Cholesterol	1.0	1.5	3.8	1.1	0.8	0.7	1.3	0.4	0.5	2.0	1.2	-0.7	1.8	1.7	1.1	1.2	1.6	1.2	1.9	0.9
Hand grip strength (left)	1.0	2.6	9.9	-2.4	-0.7	-3.1	-1.0	0.6	-2.6	-1.8	-2.7	-0.8	-1.1	0.1	-0.1	-1.1	-1.4	1.2	-1.2	-1.8
Systolic blood pressure, automated reading	1.0	2.9	9.7	-1.8	0.7	-0.4	0.3	-0.8	-0.3	-2.5	-2.4	2.9	-3.1	-0.3	-2.0	-1.2	-2.1	-1.6	-0.6	-2.1
Average weekly fortified wine intake	1.0	1.2	3.2	-1.8	-0.5	-0.9	-1.3	0.3	-1.4	-1.1	-1.6	0.0	-1.2	-1.2	-0.9	-1.5	-1.3	-0.2	-1.3	-0.8
Fed-up feelings	1.0	1.8	6.0	1.4	-0.2	1.5	1.8	0.1	2.0	2.5	2.3	0.0	1.3	-0.4	-0.2	1.1	0.6	-1.0	1.5	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	5.3	1.3	-0.1	2.1	0.7	0.5	1.3	1.4	2.3	0.9	1.3	-0.6	-0.1	0.6	1.2	-0.6	0.7	1.4
High blood pressure	1.0	2.7	6.4	2.4	0.8	0.9	0.6	1.5	0.0	1.9	1.2	-1.8	2.0	1.7	2.3	2.2	2.5	2.0	0.9	1.4
Medication: Atenolol	1.0	1.3	3.5	-0.8	1.6	0.1	0.7	-1.9	0.6	-1.7	-1.9	1.3	-1.7	-0.5	-0.1	0.6	-1.4	-0.2	0.1	-1.5
Medication: Levothyroxine sodium	1.0	1.8	6.1	1.3	-0.0	1.0	-0.8	2.1	-1.1	0.3	0.8	-0.7	2.1	1.4	2.2	1.0	2.5	1.8	0.4	0.6
Neuroticism score	1.0	2.2	8.5	1.3	0.2	1.3	1.5	0.2	1.5	2.9	2.3	-0.7	2.0	-0.3	-0.1	1.2	1.2	0.0	1.6	2.7
Breastfed as a baby	1.0	1.3	5.5	-1.6	-0.6	-1.2	-1.0	-0.6	-1.6	-0.3	-0.6	0.7	-0.8	-0.5	-1.7	-2.4	-1.5	-0.8	-0.8	-0.9
Glaucoma (self-reported)	1.0	1.1	4.2	0.9	1.1	0.5	0.3	1.2	-0.3	-0.2	-0.2	-1.4	0.8	0.9	2.0	1.7	1.0	2.1	0.7	0.9
Medication: Ventolin 100micrograms inhaler	1.0	1.3	5.2	0.5	0.9	0.8	1.3	-1.4	2.3	-0.0	0.6	1.6	-0.8	-0.7	-1.6	0.0	-1.3	-2.1	0.9	-0.0
Birth weight	1.0	2.3	10.7	0.5	-1.7	-0.7	-2.5	1.6	-3.3	-1.6	-0.3	0.3	0.6	0.7	2.3	-0.4	1.6	2.1	-1.4	-0.2
Age at first live birth	1.0	1.8	5.5	-2.3	-0.9	-1.3	-0.4	-1.2	0.3	0.1	-0.7	1.2	-1.0	-1.7	-2.2	-1.7	-2.1	-1.4	-1.2	-0.9
Shortness of breath walking on level ground	1.0	1.2	2.7	0.8	1.1	1.0	1.4	-1.6	1.5	0.9	1.2	1.2	0.4	-0.6	-1.5	0.1	-0.7	-1.4	1.4	1.0
Angina (self-reported)	1.0	1.3	3.6	-0.2	1.8	0.9	1.9	-1.6	1.4	0.0	-1.1	1.0	-0.8	0.5	-1.8	0.8	-1.2	-1.0	1.4	0.8
Mean time to correctly identify matches	1.0	1.9	7.6	1.5	-0.3	1.4	-0.4	1.6	-0.9	0.0	0.7	-1.0	2.0	0.8	2.1	1.2	2.5	2.8	0.7	0.9
Supplements: Vitamin C	1.0	1.2	3.5	-0.2	0.1	0.6	1.8	-0.9	1.5	0.7	1.4	1.5	-0.3	-1.4	-1.9	-0.3	-1.2	-1.7	0.5	0.2
Illnesses of father: High blood pressure	1.0	1.2	2.9	-1.5	-1.4	-1.7	-1.7	1.0	-1.3	-1.0	-1.5	-1.3	0.1	-0.6	0.6	-0.9	-0.1	0.1	-1.1	-1.0
Ever smoked	1.0	1.7	7.1	0.1	-0.8	-0.9	-0.1	2.1	-1.3	0.6	-0.6	-2.7	1.3	1.6	1.8	1.0	1.3	2.3	-0.1	0.0
Ever had prostate specific antigen (PSA) test	1.0	1.2	4.0	-0.5	1.1	0.3	0.5	-1.6	0.4	-0.1	-0.4	1.6	-2.0	-1.2	-1.5	-0.6	-1.9	-1.6	-0.2	-0.4
Neuroticism	0.9	2.2	8.0	1.5	0.3	1.1	1.0	0.5	1.2	2.8	2.1	-0.8	2.3	0.4	0.4	1.3	1.7	0.3	1.5	2.8
Allergy	0.9	2.0	6.8	-0.4	-2.1	-1.4	-2.6	1.4	-2.6	-1.0	-0.1	0.9	0.1	-0.8	1.0	-1.4	1.0	1.0	-2.2	-1.0
Time employed in main current job	0.9	1.0	4.1	-0.1	-0.1	0.2	-0.4	-1.5	-0.6	-1.6	0.3	2.0	-1.0	-1.0	-1.5	-1.6	-1.0	-0.9	-0.5	-0.5
Pulse rate	0.9	1.5	7.5	-0.9	-1.5	-1.4	-1.4	2.7	-1.9	0.2	-0.9	-1.2	0.4	0.3	1.0	-0.3	1.1	1.5	-1.3	-0.4
Standing height	0.9	9.0	26.5	3.0	1.7	1.5	1.7	2.0	0.9	-0.0	1.1	-3.3	2.9	3.3	4.5	4.7	4.4	5.2	2.8	3.5
Age at last live birth	0.9	1.3	4.0	-1.7	-0.5	-0.3	-0.3	-0.7	1.1	-0.6	-0.7	0.8	-1.4	-2.0	-1.3	-0.8	-1.9	-1.2	-1.2	-1.2
Knee pain experienced in last month	0.9	1.4	4.9	1.2	0.3	0.7	1.7	-0.8	1.9	1.8	2.2	-0.3	1.4	-0.3	-0.4	0.9	0.6	-0.5	1.2	1.7
Wears glasses or contact lenses	0.9	1.0	3.5	-0.9	-1.7	-1.9	-1.3	0.3	-1.3	-0.4	-0.8	0.2	-0.7	-1.0	-0.8	-1.4	-0.6	-0.0	-1.4	-0.3
Alzheimer’s Disease (in father)	0.8	0.8	3.6	1.2	0.3	1.9	0.4	-0.1	0.2	0.4	1.8	1.4	0.9	0.7	-0.3	0.0	0.9	-0.7	0.9	0.9
Ulcerative Colitis (UC)	0.8	1.5	8.8	-1.6	-1.7	-3.0	-0.9	-0.2	-1.6	-0.9	-1.8	-0.1	-0.6	-0.5	-0.6	-1.0	-0.7	0.1	-1.3	-1.2
Fasting Glucose	0.8	0.9	2.7	1.3	0.6	1.6	1.1	-0.9	0.0	0.7	1.4	0.3	0.5	1.6	0.7	1.0	0.8	-0.3	1.2	0.7
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.3	0.2	-1.0	-0.9	-1.3	0.9	-1.4	0.2	-0.0	-0.6	1.4	1.1	1.5	0.3	1.5	0.9	-0.2	0.4
Height	0.8	15.5	43.0	4.8	4.0	3.5	3.5	1.0	1.9	-0.5	1.4	-3.2	3.0	4.0	5.1	6.6	5.2	6.3	4.7	3.9
Relative age of first facial hair	0.8	1.6	4.8	0.7	1.5	2.2	1.8	-1.3	2.2	1.6	1.5	0.7	-0.0	-0.1	-1.0	0.4	-0.9	-1.9	1.3	-0.2
Had other major operations	0.8	0.9	3.6	1.6	0.8	1.4	0.6	-1.2	0.2	1.1	1.9	1.1	0.7	0.4	0.2	0.4	0.8	-0.7	0.5	1.3
Illnesses of siblings	0.8	1.2	3.8	-1.3	-0.9	-1.2	-0.8	-0.2	-0.4	-0.0	-0.0	0.2	-1.0	-1.8	-1.4	-1.3	-1.5	-1.9	-1.2	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	6.6	0.3	-0.9	0.8	0.7	-0.6	1.4	2.6	1.6	0.9	0.9	-1.8	-1.6	-0.5	-0.1	-1.0	0.1	0.2
Birth weight of first child	0.8	1.4	6.4	-0.2	-1.1	-0.6	-1.9	2.5	-1.7	-1.5	0.2	-1.1	0.7	-0.1	1.6	-0.6	1.4	1.2	-0.9	-0.0
Gout (self-reported)	0.8	1.1	3.6	-0.5	1.5	0.2	0.8	-1.2	0.6	-0.8	-1.2	1.8	-1.9	0.1	-0.9	0.2	-1.4	-1.5	0.1	-0.7
Qualifications: College or University degree	0.8	2.5	11.3	-1.4	1.5	0.3	1.5	-2.5	0.6	0.4	-0.9	0.5	-1.8	-0.8	-2.8	-0.7	-3.4	-2.5	0.7	-0.5
Eye problems/disorders: None of the above	0.8	0.9	2.7	-1.6	0.2	-0.3	-0.4	-0.9	0.0	-1.1	-1.5	0.6	-1.7	-0.2	-0.9	-0.9	-1.4	-0.8	-0.6	-1.4
Mouth/teeth dental problems: Loose teeth	0.8	1.0	3.3	1.0	-0.5	-0.8	-0.3	0.4	-0.6	0.0	0.4	-0.8	1.6	1.2	1.6	0.6	1.8	1.8	0.1	0.7
Alcohol intake frequency.	0.8	1.9	5.3	2.2	-0.5	0.7	0.7	-0.2	1.0	1.8	2.1	0.0	2.2	0.4	1.2	1.6	2.0	0.4	1.0	2.3
Suffer from ‘nerves’	0.8	1.2	5.3	0.2	-0.9	-0.6	0.8	1.3	0.8	2.3	0.8	-1.9	1.9	-0.0	-0.5	0.8	0.7	0.5	0.7	1.7
Mood swings	0.8	1.5	4.8	0.7	0.3	1.8	1.7	-0.7	2.2	2.0	2.0	-0.4	0.8	-0.7	-0.5	0.9	-0.0	-0.9	1.4	1.4
Loneliness, isolation	0.8	1.1	4.9	1.4	-1.2	0.6	0.6	0.6	0.6	2.2	2.0	0.1	1.2	-0.6	-0.0	0.6	1.2	-0.4	0.2	1.3
Mother’s age at death	0.8	1.0	2.6	-1.6	-1.2	0.4	-0.5	-0.8	-1.0	-1.2	-1.2	1.0	-1.3	-0.9	-1.0	-1.0	-1.3	-0.4	-1.2	-1.0
Tinnitus: Yes, now most or all of the time	0.8	1.0	4.3	-0.5	0.4	0.7	0.4	-1.0	-0.3	-0.8	-0.9	1.3	-2.1	-0.9	-1.3	-0.2	-1.6	-1.4	-0.6	-0.5
Eye problems/disorders: Glaucoma	0.8	0.9	3.8	0.5	0.3	0.3	-0.2	1.7	-0.8	-0.2	-0.5	-1.1	0.8	0.6	2.0	1.2	1.1	1.8	0.2	0.3
Medication: Atorvastatin	0.8	1.0	3.3	0.9	1.4	1.3	1.8	-1.2	0.4	0.4	0.0	0.5	0.4	0.7	0.3	1.4	0.6	1.6	1.5	0.9
Average weekly beer plus cider intake	0.8	1.1	4.4	0.2	-0.7	0.9	-1.1	1.2	-2.1	0.3	-0.2	-0.6	1.3	1.7	1.6	0.3	1.5	1.3	0.2	0.4
Depressed Affect (Nagel 2018)	0.7	1.4	6.1	0.9	-0.2	1.8	1.4	-0.6	1.2	2.5	2.0	0.5	1.1	-0.4	-0.7	0.4	0.1	-1.2	1.3	1.3
Prostate Cancer	0.7	0.9	2.4	1.3	0.3	1.1	0.2	-0.0	-1.0	0.9	1.5	0.5	1.2	1.5	0.8	0.3	1.6	0.5	0.9	1.1
Blood White Count	0.7	5.2	10.6	-3.1	-2.0	-3.3	-3.0	-0.7	-2.5	-2.7	-2.5	2.0	-2.0	-1.3	-0.9	-3.1	-1.3	-0.7	-2.7	-3.2
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	6.6	0.2	-0.2	-0.2	-0.3	-1.0	-0.2	0.4	0.7	1.6	-0.5	-0.9	-1.3	-1.1	-1.1	-2.6	-0.3	-0.2
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.7	1.1	1.1	1.6	1.1	-1.3	1.2	-1.0	0.0	0.9	-0.1	0.2	0.1	1.3	0.2	0.1	0.9	-0.0
Diabetes (mother)	0.7	0.9	2.4	1.2	-0.7	0.6	0.3	0.8	1.4	0.9	1.6	0.8	1.4	-0.9	0.5	0.4	1.5	0.5	0.2	1.2
Leg fat-free mass (left)	0.7	3.4	11.3	1.7	0.2	1.0	0.4	2.4	-0.1	-0.4	0.2	-1.9	2.0	1.8	3.4	3.0	3.0	2.9	1.0	1.6
Townsend deprivation index at recruitment	0.7	1.0	3.2	1.5	1.7	0.8	0.6	0.5	0.4	-0.2	0.3	-0.5	0.1	1.5	1.8	1.6	1.4	0.8	0.6	-0.2
Maternal smoking around birth	0.7	1.0	2.8	1.7	0.4	0.9	0.2	0.9	0.7	1.0	0.8	-0.6	0.9	1.3	1.5	1.5	1.6	1.0	0.7	1.0
Nervous feelings	0.7	1.3	5.3	0.5	0.2	0.7	1.0	-0.3	1.9	2.0	1.4	-0.6	1.5	-0.0	-1.2	0.6	0.5	-0.1	1.4	2.3
Medication: Simvastatin	0.7	1.1	3.4	0.9	1.4	0.6	0.2	0.4	0.1	-1.0	-0.7	-1.1	0.1	1.1	1.4	1.4	1.1	1.8	1.0	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	3.6	0.5	0.8	1.5	1.8	-0.2	1.9	1.2	0.9	-0.3	0.2	0.4	-0.9	1.0	-0.0	-1.5	1.6	0.8
Happiness	0.7	0.8	3.9	0.6	-0.8	-0.0	0.1	-0.6	0.5	-0.1	0.5	1.6	-1.0	-2.0	-0.9	-0.2	-0.7	-1.7	-1.2	-0.0
Prospective memory result	0.7	0.9	2.9	1.2	0.4	0.8	-0.3	1.1	0.2	0.6	1.0	-0.7	1.7	1.1	1.4	0.7	1.7	0.5	0.8	0.7
Headache pain in last month	0.7	1.1	3.7	0.2	-1.6	-0.8	0.4	1.5	0.6	1.3	1.5	0.3	0.6	-1.9	-1.7	-0.6	0.1	-1.1	-0.7	1.1
Exposure to tobacco smoke outside home	0.7	1.0	3.2	0.7	0.1	1.4	1.4	0.3	1.2	1.8	1.2	-0.6	0.9	0.5	-0.3	1.0	0.1	-1.3	0.7	1.6
Medication: Blood pressure	0.7	1.3	5.7	-0.1	-0.5	-0.4	-0.9	2.4	-1.1	0.9	-0.6	-2.1	1.2	0.7	1.5	0.6	1.4	1.6	-0.2	0.3
Pulse rate, automated reading	0.7	2.3	7.7	-1.4	-2.1	-2.8	-1.9	1.7	-2.6	-0.9	-1.6	-0.0	-0.6	-0.7	0.3	-1.1	0.3	0.6	-2.3	-1.6
Chest pain or discomfort	0.7	1.0	5.5	0.7	1.2	1.3	1.3	-0.3	2.3	0.2	0.1	0.4	-0.2	1.2	-0.8	0.8	-0.2	-1.0	1.8	0.8
Hypertension (Self-reported)	0.7	1.8	5.1	2.0	0.7	0.8	0.3	1.3	-0.1	1.2	0.7	-1.3	1.3	1.7	2.2	1.9	2.2	1.7	0.6	0.9
Ever taken oral contraceptive pill	0.7	0.8	2.8	-1.6	-0.3	-1.2	-1.2	0.4	-1.1	-1.2	-1.7	-0.7	-0.2	-0.2	0.3	-0.6	-0.3	0.7	-0.7	-0.9
Crohns Disease (2017)	0.6	1.3	12.1	-0.5	-0.2	-1.0	-0.8	0.6	-3.5	-1.1	-1.6	-0.7	-0.5	1.4	1.2	0.0	-0.0	1.1	-0.4	-0.2
Mean Putamen Volume	0.6	0.7	2.9	-0.0	0.3	-0.0	0.1	1.2	-1.1	0.0	-0.5	-1.7	0.6	0.8	1.6	0.9	0.8	1.1	0.2	0.7
Lupus	0.6	1.0	3.4	1.0	0.2	1.0	0.0	1.3	0.9	0.5	1.7	-1.1	1.9	0.4	0.4	0.2	1.3	-0.2	0.9	1.3
Sensitivity / hurt feelings	0.6	1.0	3.5	0.6	-0.3	1.0	0.7	-0.8	1.5	1.3	1.8	0.5	0.8	-0.4	-1.0	-0.2	0.0	-1.9	1.0	1.4
Vitamin and mineral supplements	0.6	0.8	2.8	0.4	-0.5	-1.3	-1.7	0.2	-1.4	-1.2	-1.0	0.2	-0.5	-0.3	0.7	-0.2	0.4	1.5	-1.2	0.1
Supplements: Zinc	0.6	0.6	3.0	-0.3	-0.1	1.7	0.8	0.4	1.0	-0.3	0.7	1.0	-0.3	-0.2	-0.8	-0.2	-0.7	-1.7	0.4	-0.1
Medication: Co-codamol	0.6	0.7	1.7	-1.2	-0.9	-1.1	-0.8	0.4	-0.7	-0.1	-0.2	0.1	-0.6	-1.2	-1.0	-1.3	-0.6	-0.5	-1.2	-0.9
Medication: Metformin	0.6	0.8	4.0	1.0	-0.1	0.2	-0.7	1.6	-0.2	-0.8	0.4	-0.1	1.0	0.4	1.3	0.6	2.0	1.5	0.0	0.4
Diabetes (father)	0.6	0.8	3.0	-0.8	-1.3	-0.6	-1.7	0.8	-0.3	0.0	0.4	0.6	0.0	-1.2	-0.8	-1.4	-0.3	-1.2	-1.2	-0.2
Leg predicted mass (left)	0.6	3.4	10.8	1.7	0.2	1.1	0.4	2.4	-0.1	-0.3	0.2	-1.9	2.0	1.7	3.3	3.0	3.0	2.8	1.0	1.6
Hair/balding pattern: Pattern 2	0.6	0.8	3.6	0.6	1.1	0.4	1.3	-1.5	0.5	1.9	0.7	0.0	0.6	1.1	-0.1	0.8	0.1	-0.4	1.2	0.4
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.8	-1.3	-1.1	-0.6	-1.0	0.3	-1.7	-0.2	-1.4	-0.1	0.3	-0.5	0.4	0.1	-0.1	1.1	-1.1	0.4
Fluid intelligence score	0.6	1.2	5.5	-1.1	-0.0	-0.5	0.3	-1.6	0.6	-0.1	-0.3	0.3	-1.3	-0.7	-2.0	-0.9	-2.2	-2.3	-0.4	0.0
Trunk fat-free mass	0.6	3.4	10.4	1.4	1.6	0.4	0.9	2.2	0.7	-1.5	-0.8	-2.1	0.7	1.9	3.1	3.2	2.4	3.2	1.3	1.3
Falls in the last year	0.6	0.8	2.2	1.1	1.3	1.3	1.2	-0.1	1.0	0.2	0.7	-0.1	0.4	1.1	0.5	0.8	0.7	-0.4	1.5	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.4	-1.5	0.2	-0.8	-0.0	-0.6	0.3	0.2	-1.3	-0.1	-0.7	-0.1	-1.5	-1.0	-1.5	-1.2	0.4	0.1
Depression (self-reported)	0.6	0.7	3.0	1.0	0.9	1.7	0.9	0.1	0.8	1.4	1.0	0.5	0.9	0.4	0.0	0.5	0.7	-0.2	0.9	0.8
Illnesses of mother	0.6	0.8	2.7	-1.4	-0.3	-0.9	-0.1	-0.5	-0.3	-1.0	-1.2	0.2	-1.2	-0.1	-1.0	-0.8	-1.6	-0.8	-0.4	-1.3
Trunk predicted mass	0.6	3.5	10.6	1.4	1.5	0.4	0.9	2.3	0.7	-1.5	-0.7	-2.1	0.8	1.8	3.1	3.2	2.5	3.3	1.2	1.4
Loud music exposure frequency	0.6	0.7	1.7	-0.8	-1.0	-0.8	-0.7	-0.7	-0.4	-0.1	-0.4	1.3	-0.8	-0.9	-0.7	-1.2	-0.8	-1.2	-0.8	-0.6
High blood pressure (siblings)	0.6	0.9	2.1	0.8	0.4	1.1	1.5	0.6	0.6	1.0	0.4	-1.0	1.2	0.6	0.3	1.2	1.0	1.4	1.4	0.9
Worry too long after embarrassment	0.6	1.0	4.7	0.1	-1.2	-0.3	-1.0	0.8	-0.4	1.5	0.3	-1.4	2.2	-0.1	0.7	0.5	1.2	0.5	-0.2	1.8
Whole body fat-free mass	0.6	3.3	10.0	1.6	1.0	0.7	0.8	2.3	0.5	-1.0	-0.3	-1.9	1.2	1.8	3.1	3.2	2.7	3.0	1.2	1.5
Leg fat-free mass (right)	0.6	3.4	10.5	1.8	0.1	1.1	0.2	2.4	-0.2	-0.3	0.3	-1.7	2.1	1.7	3.2	2.9	3.0	2.8	1.0	1.6
Commuting to job workplace: Walk	0.6	0.6	2.3	-0.3	1.2	0.4	0.6	-1.0	0.3	0.4	-0.6	0.3	-1.0	1.1	-0.6	-0.3	-1.2	-1.5	0.6	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	3.2	-0.2	-0.9	-0.1	-1.2	1.3	-0.7	-1.8	-0.1	0.8	-0.6	-1.0	0.2	-0.8	-0.1	0.1	-1.2	-0.3
Osteoporosis (self-reported)	0.6	0.8	2.5	-0.7	0.7	1.0	0.4	-1.2	0.0	-0.2	-0.9	0.7	-1.6	-1.1	-1.1	-0.3	-1.3	-1.0	0.2	-1.1
Whole body water mass	0.6	3.2	9.9	1.5	1.0	0.8	0.8	2.2	0.5	-1.0	-0.3	-1.8	1.2	1.8	3.1	3.1	2.6	3.0	1.1	1.5
Leg predicted mass (right)	0.6	3.3	10.7	1.8	0.1	1.1	0.2	2.4	-0.2	-0.4	0.3	-1.7	2.1	1.6	3.3	2.9	3.0	2.8	0.9	1.6
Medication: Bendroflumethiazide	0.6	1.0	2.8	0.0	-0.8	-1.0	-0.8	1.5	-1.4	0.3	-0.3	-1.6	1.0	0.5	1.2	0.3	1.2	1.7	-1.0	-0.4
Heart attack/myocardial infarction (self-reported)	0.6	0.7	3.2	1.3	1.8	0.7	1.2	-0.8	0.4	-1.3	-0.4	0.1	-0.6	0.5	0.3	1.1	0.1	0.2	1.2	0.5
Depression (Nagel 2018)	0.5	0.8	3.4	0.8	-0.2	1.8	0.7	0.2	0.5	1.3	1.8	1.1	0.6	-0.3	-0.6	-0.0	0.5	-1.2	0.4	0.9
Irritable Bowel Disease (IBD)	0.5	1.2	7.1	-0.9	-1.1	-2.3	-0.7	0.5	-2.7	-0.6	-1.7	-1.0	-0.3	0.9	0.5	-0.2	-0.2	0.7	-0.7	-0.5
HDL Cholesterol	0.5	0.8	2.7	0.9	1.7	1.6	1.0	-1.2	0.1	-0.1	0.3	0.1	0.2	0.5	0.6	0.8	0.2	0.9	1.6	1.0
Systolic Blood Pressure	0.5	2.7	9.4	-1.8	1.9	-0.8	0.1	-0.7	-1.1	-2.9	-2.9	1.8	-3.1	0.4	-0.9	-0.5	-1.9	-0.4	-0.2	-2.3
Allergy or Eczema	0.5	1.3	4.3	-0.8	0.9	-0.7	1.8	-1.2	1.3	1.3	-0.5	-1.5	-0.9	-0.1	-1.7	0.1	-2.1	-1.7	0.8	0.0
Type 2 Diabetes (T2D) (2018)	0.5	1.0	2.6	0.3	-1.1	-0.2	-1.6	1.5	-1.1	-0.4	0.8	-0.1	1.6	-0.6	0.8	-0.7	1.6	1.5	-0.7	0.4
Hand grip strength (right)	0.5	1.2	4.9	-1.1	0.0	-1.8	-0.6	0.6	-2.0	-1.2	-1.7	-1.0	-0.3	1.1	1.1	0.1	-0.3	2.2	-0.2	-0.7
Hayfever, allergic rhinitis or eczema	0.5	1.0	3.0	-0.6	1.0	0.0	1.5	-1.4	1.7	0.8	-0.5	-0.8	-0.8	0.2	-1.1	0.3	-1.6	-1.5	1.1	0.1
Multivitamins +/- minerals	0.5	0.7	2.4	-0.4	-0.3	0.3	-0.1	1.6	0.1	0.3	0.2	-1.4	1.2	1.4	1.2	0.3	1.1	0.7	0.5	-0.1
Stomach or abdominal pain in last month	0.5	0.7	2.8	0.9	0.9	1.0	1.7	-1.0	1.1	0.4	1.0	0.3	0.1	0.6	0.3	1.0	0.4	0.0	1.2	0.6
Sitting height	0.5	3.6	31.7	-1.3	0.6	-0.3	-1.6	2.0	-0.4	-5.6	-2.9	0.1	-2.5	-1.1	1.1	0.1	0.0	2.0	-1.0	-1.2
Number of incorrect matches in round	0.5	0.8	3.2	-0.9	-1.5	-1.8	-1.0	-0.3	-1.0	0.1	-0.3	0.3	-0.2	-0.6	-0.7	-1.4	-0.5	-0.4	-1.5	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.7	0.8	0.9	1.6	1.6	-0.0	1.6	0.7	0.3	-0.2	0.2	0.2	-0.2	1.3	0.2	-1.0	1.3	0.7
Financial difficulties in last 2 years	0.5	0.7	2.7	1.0	-0.1	0.3	0.5	0.5	0.8	1.3	1.6	0.3	1.3	0.3	0.2	0.6	1.1	-0.1	0.6	1.2
Heart attack	0.5	0.7	3.0	1.1	1.7	0.7	1.2	-1.1	0.4	-1.4	-0.5	0.4	-0.8	0.5	0.1	0.9	-0.2	-0.0	1.1	0.4
Tense / ‘highly strung’	0.5	0.9	4.0	0.8	0.5	1.0	1.1	-0.5	1.3	2.0	1.3	-0.2	1.0	0.3	-0.1	0.9	0.7	-0.2	1.2	1.3
Pulse wave reflection index	0.5	0.6	2.2	0.7	1.0	1.0	1.2	-0.2	1.5	-0.2	0.4	-0.8	0.4	0.2	0.4	1.3	0.4	0.3	0.8	0.5
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.0	1.1	-0.8	-0.4	0.1	0.5	0.6	0.8	1.2	-0.1	1.1	-0.4	0.0	0.0	1.3	0.6	0.3	1.4
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	3.2	0.1	-0.6	-0.1	0.5	-1.5	0.8	-0.0	1.2	1.7	-0.5	-0.8	-1.4	-1.0	-0.9	-1.8	-0.1	-0.3
Medication: Seretide 50 evohaler	0.5	0.6	2.8	1.2	0.7	1.3	0.7	-0.6	1.7	-0.0	0.5	1.0	-0.4	0.2	-0.3	0.8	0.0	-0.9	0.8	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.7	-1.2	1.2	-0.0	0.8	-0.9	0.3	-0.3	-1.6	-0.2	-0.7	-0.0	-0.8	0.5	-1.1	0.5	0.6	-0.3
Arm predicted mass (right)	0.5	2.3	9.5	1.3	1.4	0.7	1.4	1.6	1.1	-1.2	-0.7	-1.2	0.2	1.6	2.4	3.1	1.7	2.2	1.2	1.1
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.0	-0.3	0.9	0.4	-0.5	-1.0	-0.6	-1.4	0.0	0.8	-1.3	-0.7	0.0	-1.0	-0.6	-0.2	-0.6	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	2.8	0.0	-0.4	1.2	1.2	1.7	0.4	1.1	0.2	-1.1	1.1	0.6	-0.1	1.1	0.2	0.1	1.0	1.0
Financial situation satisfaction	0.5	0.6	1.6	1.2	-0.3	0.1	0.1	1.0	0.3	0.6	0.6	-0.7	0.7	1.2	1.1	1.1	1.3	0.1	0.3	1.2
Basal metabolic rate	0.5	2.8	9.5	1.6	1.0	0.8	0.9	1.9	0.6	-0.9	-0.1	-1.6	1.1	1.7	2.9	3.1	2.4	2.6	1.2	1.4
Leg fat percentage (left)	0.5	1.7	5.8	-0.4	0.6	0.1	1.3	-1.5	1.1	-1.0	-0.3	2.2	-2.0	-0.8	-1.6	-0.3	-2.0	-2.4	0.1	-1.0
Myopia	0.5	0.7	2.5	0.2	1.4	1.0	0.0	0.5	0.9	-1.6	-0.4	-0.8	-0.6	1.4	0.9	1.0	0.2	-0.8	0.4	0.3
Heart disease (siblings)	0.5	0.6	3.1	0.6	1.1	0.8	1.0	-1.8	1.1	0.2	-0.2	0.5	-0.1	1.0	-0.1	0.6	-0.1	0.2	0.9	0.7
Major Depression (MDD)	0.4	0.5	1.5	-1.2	-0.6	-0.9	-0.4	0.4	-0.3	0.6	-0.7	0.0	-0.2	-0.8	-0.8	-1.1	-1.0	-0.5	-0.7	-0.8
Blood Platelet Count	0.4	4.5	14.5	-2.3	0.0	-3.2	-1.3	0.2	-2.2	-3.8	-3.8	-0.3	-2.9	0.1	0.3	-1.6	-1.6	0.5	-1.8	-3.6
Impedance of leg (right)	0.4	2.0	7.6	-0.2	2.1	0.0	2.1	-2.8	2.4	0.3	0.1	0.4	-1.5	0.3	-1.6	0.2	-1.9	-1.6	1.5	0.4
Age when periods started (menarche)	0.4	1.1	4.5	0.5	-2.1	-0.3	-0.1	-0.1	0.2	0.3	2.1	1.4	0.7	-1.5	-1.3	-1.4	0.5	-0.7	-0.4	0.9
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.5	0.8	0.7	-0.6	0.8	0.8	0.1	-1.1	-0.7	-0.0	-0.8	0.8	1.1	1.2	0.3	0.6	0.3	-0.4
Impedance of leg (left)	0.4	2.1	7.3	0.1	2.0	0.4	2.2	-2.7	2.5	0.7	0.7	0.6	-1.2	0.3	-1.7	0.3	-1.7	-1.8	1.8	0.7
Had menopause	0.4	0.5	1.8	-0.3	-0.3	0.2	-0.8	-0.7	-1.3	-0.8	-0.0	0.9	-0.3	-0.1	-1.1	-1.3	-0.5	-0.7	-0.3	-0.4
Impedance of arm (right)	0.4	1.7	7.5	1.4	-1.4	0.6	-0.6	-0.4	-0.8	1.8	2.7	-0.5	2.7	0.6	0.9	-0.1	1.8	0.8	0.5	1.4
Hair/balding pattern: Pattern 3	0.4	0.7	1.8	-0.8	-0.2	0.3	0.1	-0.9	0.4	-1.3	-1.3	0.5	-1.2	-1.3	-0.6	-0.4	-1.1	-0.1	-0.4	-1.1
Noisy workplace	0.4	0.5	3.9	0.5	-0.3	0.1	-0.6	0.5	0.3	-0.6	0.2	-0.5	0.8	-0.9	0.7	0.1	1.2	2.0	0.0	0.2
Medication: Cholesterol lowering	0.4	0.6	2.4	0.1	1.2	0.2	0.0	0.7	-0.4	-0.4	-1.1	-0.8	0.2	1.2	1.0	1.0	0.6	1.6	0.5	0.6
Impedance of arm (left)	0.4	1.8	7.8	1.6	-1.3	0.9	-0.3	-0.7	-0.4	2.2	2.6	-0.5	2.8	0.7	0.9	0.2	1.8	0.7	0.7	1.4
Hair/balding pattern: Pattern 4	0.4	0.9	4.6	-0.8	0.2	-0.4	-2.1	1.2	-2.0	-1.0	-0.7	-0.1	-0.1	0.1	-0.2	-1.6	-0.1	-0.3	-0.6	0.7
Peak expiratory flow (PEF)	0.4	1.0	3.5	0.5	-1.0	-1.1	-0.4	0.8	-1.3	1.3	0.9	-1.4	1.9	0.4	1.3	0.2	1.2	1.0	-0.0	0.8
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.6	0.2	0.6	0.9	0.0	1.6	0.1	-0.1	-0.1	-0.3	0.9	0.4	0.5	0.6	0.9	1.4	0.8	0.6
Leg fat percentage (right)	0.4	1.5	4.4	-0.5	0.8	-0.1	1.3	-1.4	1.1	-1.1	-0.6	1.9	-2.1	-0.7	-1.4	-0.3	-1.9	-2.1	0.1	-1.1
Arm fat-free mass (right)	0.4	2.1	8.9	1.3	1.5	0.9	1.5	1.3	1.4	-1.1	-0.5	-0.9	0.2	1.6	2.1	3.0	1.6	1.9	1.3	1.2
Family relationship satisfaction	0.4	0.5	2.7	0.8	0.1	-0.2	0.4	-0.0	1.1	1.6	0.8	-0.3	0.8	-0.2	-0.2	0.4	0.6	0.1	0.5	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.8	-0.9	-0.9	-0.2	-0.7	-0.5	-0.8	-0.9	-1.4	0.0	-0.7	-0.6	0.0	-0.3	-0.5	0.2	-0.9	-0.6
Commuting to job workplace: Public transport	0.4	0.5	2.1	-1.1	0.0	-0.2	0.1	-0.4	-0.7	0.1	-0.9	0.5	-0.7	-0.1	-1.5	-0.7	-1.0	-0.9	-0.6	-0.4
Arm fat-free mass (left)	0.4	2.0	7.9	1.2	1.6	0.7	1.5	1.3	1.2	-1.0	-0.4	-1.2	0.3	1.5	2.1	2.8	1.5	1.9	1.4	1.1
Cholesterol lowering medication	0.4	0.6	2.8	1.2	-0.1	0.5	0.2	-0.9	-0.2	-0.1	1.1	0.3	1.0	-0.4	0.1	0.4	1.0	1.5	0.6	1.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.1	1.4	0.0	-0.0	0.2	0.4	0.5	1.0	1.2	0.0	1.1	0.0	0.2	0.1	1.0	0.3	0.3	1.0
Pain experienced in last month	0.4	0.6	2.3	-0.4	0.9	0.5	-0.9	-0.6	-0.6	-1.3	-1.5	-0.1	-0.9	1.2	1.1	0.3	-0.6	0.3	0.3	-1.0
Arm predicted mass (left)	0.4	2.0	8.3	1.3	1.5	0.6	1.5	1.3	1.3	-1.0	-0.4	-1.2	0.2	1.5	2.1	2.9	1.5	1.9	1.3	1.2
Bipolar Disorder or Schizophrenia	0.3	0.7	3.9	0.9	-0.7	0.8	-0.0	0.8	0.8	1.3	2.0	1.0	1.2	0.0	0.2	-0.3	0.6	-0.8	0.2	0.8
Schizophrenia (2018)	0.3	0.7	3.0	1.1	-0.2	1.3	0.5	-0.2	1.1	1.0	1.7	1.3	0.9	-0.1	0.0	0.1	0.4	-0.7	0.5	0.6
Schizophrenia vs Biploar Disorder	0.3	0.4	1.9	0.8	0.1	0.6	0.7	-0.8	0.9	-0.0	0.5	1.4	-0.1	-0.7	-0.7	0.2	-0.0	-0.5	0.1	0.1
Alzheimer’s Disease (in mother)	0.3	0.3	2.0	-0.9	0.5	-0.1	-0.2	-0.3	-0.6	-0.2	-0.4	-0.8	-0.7	0.6	-0.1	-0.3	-0.6	-1.4	0.1	-0.2
Primary Biliary Cirrhosis	0.3	0.5	2.1	0.7	1.1	0.2	-0.3	-0.4	-0.2	-0.6	-0.4	-0.6	-0.1	1.4	1.4	0.6	0.5	0.6	0.6	0.2
Schizophrenia (2014)	0.3	0.6	4.5	0.4	-0.5	0.8	-0.2	-0.3	0.7	-0.4	0.9	2.1	-0.3	-0.6	-0.3	-0.5	-0.4	-1.4	-0.3	-0.2
Triglycerides	0.3	0.4	1.6	-0.3	-1.3	-1.1	-0.5	0.7	0.2	0.6	0.4	-0.2	0.5	-0.4	-0.5	-0.9	0.5	-0.6	-0.9	-0.6
BMI	0.3	1.9	4.5	-1.7	-1.1	-0.8	-0.3	-0.8	-0.1	-0.9	-1.5	2.1	-1.9	-1.4	-1.3	-0.8	-1.9	-1.9	-1.6	-1.9
Cardiovascular Disease	0.3	1.1	6.7	1.0	0.4	-0.1	-0.2	0.4	-0.3	0.4	-0.1	-1.4	0.9	0.5	1.8	1.5	1.7	2.6	0.3	0.1
Hypothyroidism (self reported)	0.3	0.6	2.7	-0.5	-0.8	-0.2	-1.4	0.8	-1.6	-1.0	0.3	0.7	0.3	-0.4	0.1	-1.0	0.5	0.4	-1.0	-0.6
Ever had hysterectomy (womb removed)	0.3	0.4	2.8	0.0	-0.0	0.1	0.0	0.1	-0.7	-0.8	-0.6	0.7	-0.8	-0.5	0.3	0.0	0.0	0.4	-0.7	-1.7
Current tobacco smoking	0.3	0.5	2.9	-0.8	-0.5	-1.0	-0.8	0.9	-0.5	0.2	-0.9	-0.9	0.3	-0.4	0.2	0.0	0.3	1.7	-0.3	0.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.5	-0.6	1.2	0.6	0.7	0.4	0.4	-0.2	-0.7	-0.2	-0.8	-0.1	-0.7	-0.1	-1.0	-0.4	0.5	-0.4
High blood pressure (mother)	0.3	0.5	1.4	0.3	-0.5	-0.9	-0.3	0.7	0.4	1.0	0.7	-1.2	1.1	-0.6	0.4	0.2	0.8	0.8	-0.2	1.0
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.6	-0.5	-0.0	-0.0	0.7	-1.2	1.3	0.9	-0.3	-0.4	-0.6	-0.2	-0.5	0.2	-0.9	-0.9	0.1	0.2
Medication: Ramipril	0.3	0.3	0.9	-0.1	-0.2	-0.8	-0.6	0.0	-0.9	-1.0	-0.6	0.9	-0.5	-0.1	0.5	-0.5	-0.5	0.4	-0.9	-0.4
Pulse wave Arterial Stiffness index	0.3	0.3	1.1	0.6	0.5	0.3	0.9	-0.1	1.1	0.7	0.9	-0.4	0.5	-0.5	-0.3	0.7	0.4	0.1	0.0	0.6
Exposure to tobacco smoke at home	0.3	0.3	1.5	-0.0	1.2	0.2	0.5	-1.2	0.1	-0.3	-0.4	0.5	-0.8	0.4	-0.1	0.5	-0.7	-0.2	0.3	0.6
Medication: Paracetamol	0.3	0.5	2.0	-0.7	-1.0	-1.4	-0.1	1.1	-0.4	0.3	-0.7	-0.7	0.2	-1.1	-0.0	0.1	-0.0	0.5	-0.8	-0.5
Comparative body size at age 10	0.3	0.8	2.3	-0.3	1.2	1.2	1.4	-0.4	0.8	1.5	0.2	0.1	0.4	0.7	-0.6	0.9	-0.5	-0.6	1.3	1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	2.2	-0.0	-0.1	0.3	0.4	-0.4	1.5	1.1	0.1	-1.0	0.3	0.2	-0.0	0.2	-0.4	-0.2	0.4	-0.4
Emphysema/chronic bronchitis	0.3	0.4	1.3	-1.0	0.3	0.3	-0.2	-0.3	0.2	-0.9	-1.1	1.0	-0.9	-0.1	-0.8	-0.6	-0.5	0.1	0.1	-0.0
Medication for pain relief, constipation, heartburn	0.3	0.6	2.1	-0.0	1.3	1.2	0.6	-1.0	0.5	-0.8	0.1	0.6	-1.4	0.5	-0.2	-0.0	-1.1	-0.9	0.5	-0.7
Illnesses of father: Heart disease	0.3	0.4	2.2	0.6	0.7	-0.1	0.6	-0.1	0.2	0.6	-0.2	-1.5	0.5	0.2	0.1	0.6	0.5	1.3	0.9	0.8
Long-standing illness, disability or infirmity	0.3	0.5	1.5	0.3	0.0	-0.7	-0.3	1.0	-0.3	0.1	-0.8	-1.2	0.7	0.3	1.1	0.8	0.7	1.1	0.1	0.7
Eye problems/disorders: Cataract	0.3	0.3	1.0	0.0	-0.9	-0.4	-0.4	0.4	-0.3	0.6	0.9	0.3	0.8	-1.0	-0.5	-0.8	0.3	-0.2	-0.2	-0.0
Medication: Gliclazide	0.3	0.3	1.1	0.5	-0.5	0.5	-1.1	0.6	-0.2	-0.9	0.1	0.6	0.6	0.2	0.8	0.2	1.1	0.0	-0.3	0.2
Smoking status: Current	0.3	0.4	2.9	-0.7	-0.3	-0.8	-0.7	0.9	-0.4	0.2	-0.8	-1.1	0.4	-0.2	0.2	0.1	0.2	1.7	-0.1	0.4
Medication: Blood pressure	0.3	0.6	2.6	1.6	0.9	1.6	0.5	-0.8	0.7	-0.1	0.8	0.6	0.2	0.3	0.6	1.1	0.5	0.5	0.3	0.9
Irritability	0.3	0.5	1.6	-0.1	0.3	0.3	0.1	1.2	-0.6	0.9	-0.0	-1.2	0.7	0.3	0.8	0.5	0.7	1.0	0.6	1.2
Alcohol drinker status: Previous	0.3	0.4	1.1	1.0	0.7	-0.1	0.9	-0.8	1.1	-0.1	0.0	0.3	-0.0	0.6	0.4	1.0	0.3	-0.5	0.5	0.5
Bipolar Disorder (2018)	0.2	0.4	2.1	0.0	-1.0	-0.3	-0.6	1.4	-0.1	0.6	1.0	0.1	0.8	0.1	0.3	-0.6	0.5	-0.4	-0.3	0.5
Alzheimer’s Disease (including proxy)	0.2	0.4	2.1	-0.3	0.3	0.7	0.3	-0.1	-1.0	0.6	0.2	-0.5	0.1	1.5	0.2	-0.1	0.0	-1.2	0.6	0.1
Body Mass Index (BMI) (2010)	0.2	0.2	1.0	-0.4	0.0	-0.5	-0.7	0.4	-0.3	0.0	-0.3	-0.4	-0.3	0.7	0.4	-0.4	0.1	-0.8	-0.4	-1.0
Chronic bronchitis/emphysema (father)	0.2	0.3	0.7	0.8	-0.1	0.2	0.2	0.8	0.0	0.4	0.6	-0.1	0.7	0.8	0.7	0.6	0.8	0.0	0.5	0.3
Waist circumference	0.2	0.9	2.2	1.5	0.3	1.5	1.2	-1.2	1.3	0.5	1.2	1.2	0.2	0.6	0.5	1.4	0.7	-0.6	0.8	0.5
Weight	0.2	1.1	4.3	1.3	0.3	0.8	0.8	0.8	0.4	-0.5	0.3	-0.4	0.8	1.0	1.9	2.1	1.6	1.3	0.7	0.9
Lung cancer (father)	0.2	0.3	1.3	0.5	0.5	0.0	0.9	-0.5	1.1	-0.4	0.2	1.1	-0.6	-0.5	-0.1	0.3	-0.3	0.1	0.3	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	1.9	0.5	-0.2	0.8	-0.4	0.9	-0.6	0.5	1.4	0.3	1.3	0.3	0.3	-0.3	1.1	0.5	0.1	0.6
Pulse wave peak to peak time	0.2	0.2	0.9	-0.2	-0.3	-0.2	-0.6	0.0	-0.9	-0.5	-0.7	0.1	-0.2	0.8	0.7	-0.2	-0.1	0.3	0.2	-0.3
Heart disease (mother)	0.2	0.3	1.2	0.9	-0.6	-0.2	-0.0	-0.1	0.2	1.0	0.9	0.5	0.4	-1.1	0.1	-0.1	0.5	0.0	-0.5	0.3
Had major operations	0.2	0.2	1.8	-0.1	-0.1	0.1	-0.4	1.4	0.8	0.1	-0.0	-0.5	0.2	-0.8	0.3	0.2	0.5	-0.3	-0.4	-0.1
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.2	-0.1	0.4	0.7	-0.9	-0.1	-0.7	-0.8	-0.4	0.1	-0.7	0.8	0.3	-0.1	0.0	-1.1	-0.1	0.1
Medication for cholesterol	0.2	0.3	1.2	-0.5	-0.4	-0.8	0.1	1.1	-0.1	0.6	-0.6	-1.1	0.4	0.8	0.5	0.2	0.1	-0.2	0.4	-0.6
Medication: Paracetamol	0.2	0.2	1.3	0.1	-0.7	-1.1	0.3	0.3	-0.2	0.9	-0.0	-0.4	0.3	-0.6	0.3	0.6	0.3	0.3	-0.6	-0.3
Alcohol drinker status: Never	0.2	0.2	0.8	-0.5	-0.7	-0.1	-0.3	-0.3	-0.1	0.7	-0.2	0.7	0.3	0.1	-0.7	-0.3	-0.3	-0.9	-0.2	0.6
Impedance of whole body	0.2	1.0	4.5	1.1	-0.0	0.5	0.9	-1.7	0.9	1.8	2.1	-0.1	1.3	0.5	-0.2	0.2	0.3	-0.4	1.2	1.2
Blood Eosinophil Count	0.1	0.5	3.2	-0.2	-0.4	1.3	-0.4	-0.4	0.8	-0.2	-0.3	1.8	-0.9	-0.7	-0.9	0.1	-0.8	-0.5	-0.6	-0.3
Blood Red Count	0.1	0.6	3.2	0.4	-1.8	-0.8	-0.1	1.2	0.4	0.7	0.2	-0.8	1.0	-0.8	0.3	0.9	1.0	-0.1	-1.1	-0.2
Number of treatments/medications taken	0.1	0.1	0.6	0.4	-0.2	0.2	0.3	0.0	-0.3	0.8	0.2	0.7	0.5	-0.5	-0.2	0.2	0.4	0.4	-0.3	-0.0
Pack years adult smoking proportion	0.1	0.2	0.7	-0.1	0.6	-0.5	-0.1	0.5	-0.6	0.1	-0.1	-0.7	-0.0	-0.3	0.8	0.1	0.4	0.4	-0.2	-0.3
Trunk fat percentage	0.1	0.4	1.4	0.8	-0.8	0.8	-0.0	-0.5	-0.1	0.1	1.2	1.1	0.7	0.1	0.7	0.3	0.6	-0.6	0.1	0.2
Taking other prescription medications	0.1	0.2	1.8	0.7	-0.3	0.5	-0.4	0.2	-0.4	-0.1	-0.1	1.3	0.1	-0.6	-0.0	0.1	0.3	0.2	-0.6	-0.1
Trunk fat mass	0.1	0.5	2.3	1.0	-0.5	0.7	0.1	0.4	-0.1	-0.4	0.7	0.5	0.8	0.5	1.5	1.1	1.3	0.5	0.2	0.4
Hearing difficulty/problems with background noise	0.1	0.2	1.0	0.3	0.4	0.8	-0.4	-0.0	-0.4	-0.4	0.0	1.0	-0.6	0.3	-0.1	-0.4	0.1	-0.7	-0.2	-0.5
Arm fat percentage (right)	0.1	0.4	1.7	0.4	-1.3	0.3	-0.8	0.3	-0.8	-0.2	0.8	0.9	0.6	-0.3	0.8	-0.2	0.7	-0.4	-0.6	-0.5
Hip circumference	0.1	0.2	1.1	0.0	0.4	0.5	0.5	-0.5	0.5	-1.0	-0.5	0.6	-0.4	0.3	0.6	1.1	-0.0	-0.2	0.3	0.2
Arm fat mass (right)	0.1	0.5	2.5	0.8	-0.6	0.5	-0.1	0.6	-0.3	-0.4	0.5	0.4	0.8	0.4	1.6	1.0	1.2	0.5	-0.0	0.2
Body fat percentage	0.1	0.3	1.7	0.5	-0.6	0.6	0.2	-0.6	0.1	-0.2	0.7	1.3	0.0	-0.2	0.2	0.2	0.0	-0.9	-0.0	-0.2
Number of full brothers	0.1	0.2	1.5	-0.2	-1.2	-0.2	-0.5	-0.4	0.1	0.2	-0.5	0.6	0.0	0.2	0.2	0.2	0.3	-0.2	-0.5	-0.3
Neck or shoulder pain in last month	0.1	0.1	0.8	0.3	0.6	-0.1	0.5	0.4	-0.2	-0.2	0.1	0.9	-0.0	0.1	-0.2	0.3	0.5	0.0	0.2	0.3
Medication: Allopurinol	0.1	0.2	0.7	0.1	0.9	-0.1	-0.1	0.6	-0.7	-0.6	-0.6	0.2	-0.2	0.6	0.4	0.3	0.3	0.3	0.1	0.2
Medication: Omeprazole	0.1	0.2	1.2	1.1	-0.2	-0.3	-0.0	-0.1	0.1	0.3	0.4	0.8	0.4	-0.0	-0.0	-0.2	0.4	-0.1	-0.3	0.1
Whole body fat mass	0.1	0.4	1.6	0.9	-0.5	0.7	0.4	0.5	0.1	-0.4	0.6	0.5	0.6	0.4	1.3	1.1	1.1	0.3	0.2	0.4
Leg fat mass (right)	0.1	0.4	1.1	0.3	0.6	0.4	1.0	-0.2	0.7	-0.9	-0.3	0.9	-0.8	0.3	0.4	1.0	-0.2	-0.5	0.3	-0.2
Arm fat percentage (left)	0.1	0.4	1.8	0.6	-1.3	0.5	-0.6	0.1	-0.5	0.1	0.9	1.1	0.7	-0.2	0.7	-0.1	0.6	-0.7	-0.5	-0.3
Arm fat mass (left)	0.1	0.4	1.6	0.8	-0.8	0.5	0.1	0.5	-0.1	-0.2	0.6	0.5	0.8	0.2	1.3	0.9	1.1	0.2	-0.1	0.2
Number of self-reported non-cancer illnesses	0.1	0.1	0.8	0.2	0.2	0.5	-0.1	0.1	-0.4	-0.1	-0.3	0.9	0.0	-0.1	-0.3	-0.0	0.4	-0.1	0.0	-0.1
High cholesterol (Self-reported)	0.1	0.2	1.8	-0.2	0.5	-0.4	-0.4	-0.4	0.1	-0.3	-0.2	-0.4	-0.1	-0.6	-0.1	-0.3	0.0	1.4	0.1	0.1
Number of operations (self-reported)	0.1	0.2	0.5	0.3	-0.3	-0.0	-0.7	0.5	-0.5	0.2	0.6	0.7	0.6	-0.7	0.3	-0.5	0.6	0.2	-0.7	-0.1
Pack years of smoking	0.1	0.2	0.6	-0.1	0.7	-0.4	-0.2	0.7	-0.8	-0.1	-0.1	-0.6	-0.3	-0.1	0.8	-0.1	0.3	0.2	-0.2	-0.5
Leg fat mass (left)	0.1	0.3	1.0	0.3	0.2	0.3	0.8	-0.1	0.6	-1.0	-0.2	1.0	-0.7	0.1	0.3	0.8	-0.2	-0.6	0.2	-0.2
Hair Pigment	0.0	1.0	2.7	-1.1	-1.1	-0.6	-1.6	-0.7	-1.5	-1.1	-1.6	1.1	-0.7	-0.7	-0.5	-0.7	-0.8	0.9	-1.1	-0.8
Tanning	0.0	0.3	0.9	0.1	0.6	0.2	0.5	0.6	0.3	-0.4	-0.6	-0.3	-0.6	0.4	1.0	0.8	-0.2	0.3	0.2	-0.9
Body mass index (BMI)	0.0	0.2	1.0	-0.1	-0.6	-0.0	-0.0	-0.0	-0.0	-0.3	-0.1	1.0	-0.3	-0.6	-0.0	-0.0	-0.3	-0.9	-0.5	-0.6

Hub : Genes

ZNF438

Models

Trait associations