[Hub]/) : Traits : Lung FVC :

chr10:76,664,253-79,018,276

Best TWAS P=3.38e-19 · Best GWAS P=1.59e-25 conditioned to 3.06e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia C10orf11 0.35 0.27 lasso 4 0.25 9.8e-08 8.2 -8.3 1.5e-16 -0.73 0.58 0.37 FALSE
2 GTEx Brain Cortex C10orf11 0.32 0.15 lasso 8 0.21 1.4e-06 8.4 -9.0 3.4e-19 -0.78 0.47 0.47 TRUE
3 GTEx Brain Frontal Cortex BA9 C10orf11 0.33 0.18 enet 11 0.19 9.3e-06 8.2 -8.0 1.5e-15 -0.71 0.46 0.39 FALSE
4 GTEx Muscle Skeletal C10orf11 0.11 0.13 lasso 3 0.12 5.1e-12 8.4 -8.7 2.7e-18 -0.74 1.00 0.00 FALSE
5 ROSMAP Brain Pre-frontal Cortex C10orf11 0.20 0.23 lasso 4 0.23 1.1e-29 8.4 -8.6 6.1e-18 -0.71 1.00 0.00 FALSE