[Hub]/) : Traits : Lung FVC : ← →

chr10:74,714,177-76,373,904

Best TWAS P=1.01e-17 · Best GWAS P=6.5e-18 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	BMS1P4	0.17	0.20	lasso	1	0.19	1.2e-22	5.9	-5.9	2.8e-09	-0.72	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	SEC24C	0.04	0.02	lasso	2	0.00	1.3e-01	5.6	5.7	1.2e-08	0.52	0.21	0.24	FALSE
3	GTEx	Artery Aorta	FUT11	0.07	0.04	enet	16	0.04	2.9e-03	6.1	-6.8	1.5e-11	-0.74	0.14	0.69	FALSE
4	GTEx	Artery Tibial	DUSP8P5	0.09	0.03	enet	8	0.03	2.0e-03	7.7	7.4	1.4e-13	0.84	0.21	0.51	FALSE
5	GTEx	Brain Cerebellar Hemisphere	RP11-464F9.22	0.22	0.04	lasso	4	0.07	7.3e-03	1.8	-6.6	4.5e-11	-0.60	0.03	0.46	FALSE
6	GTEx	Breast Mammary Tissue	FUT11	0.07	0.08	lasso	5	0.03	1.1e-02	5.6	-6.0	2.6e-09	-0.59	0.14	0.14	FALSE
7	GTEx	Breast Mammary Tissue (Female)	FUT11	0.11	-0.01	enet	8	0.00	2.5e-01	5.6	-7.1	1.3e-12	-0.70	0.06	0.12	FALSE
8	GTEx	Breast Mammary Tissue (Female)	ZSWIM8	0.30	0.06	lasso	5	0.04	2.5e-02	8.5	7.0	2.4e-12	0.84	0.03	0.71	FALSE
9	GTEx	Cells Transformed fibroblasts	CAMK2G	0.06	0.04	enet	10	0.06	2.2e-05	8.6	7.9	3.2e-15	0.94	0.01	0.98	FALSE
10	GTEx	Cells Transformed fibroblasts	SEC24C	0.06	0.01	lasso	5	0.01	3.9e-02	5.3	7.3	2.1e-13	0.82	0.02	0.88	FALSE
11	GTEx	Esophagus Mucosa	CAMK2G	0.10	0.04	lasso	3	0.06	4.0e-05	7.7	7.9	3.5e-15	0.89	0.06	0.88	FALSE
12	GTEx	Esophagus Mucosa	SEC24C	0.11	0.08	lasso	4	0.10	6.7e-07	5.9	-5.4	5.9e-08	-0.64	0.96	0.03	FALSE
13	GTEx	Esophagus Mucosa	FUT11	0.15	0.21	lasso	5	0.21	2.5e-14	6.0	-5.3	1.4e-07	-0.65	1.00	0.00	FALSE
14	GTEx	Nerve Tibial	AGAP5	0.08	0.01	lasso	8	0.02	2.0e-02	5.6	5.2	1.8e-07	0.69	0.03	0.94	FALSE
15	GTEx	Prostate	RP11-574K11.5	0.29	0.02	enet	43	0.00	2.4e-01	8.0	-7.1	1.3e-12	-0.47	0.02	0.39	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	AGAP5	0.11	0.07	lasso	5	0.07	1.8e-04	6.0	5.4	5.1e-08	0.67	0.28	0.40	FALSE
17	METSIM	Adipose	CAMK2G	0.11	0.05	bslmm	247	0.05	2.0e-08	5.3	-6.9	4.1e-12	-0.61	0.65	0.35	FALSE
18	YFS	Blood	CAMK2G	0.01	0.00	blup	239	0.00	5.7e-02	7.4	-6.8	7.5e-12	-0.72	0.17	0.34	FALSE
19	YFS	Blood	FUT11	0.02	0.00	bslmm	231	0.01	2.0e-03	8.6	-5.6	1.6e-08	-0.66	0.01	0.97	FALSE
20	YFS	Blood	NDST2	0.10	0.09	lasso	14	0.10	5.0e-30	8.5	-8.4	3.2e-17	-0.97	0.01	0.99	FALSE
21	YFS	Blood	PLAU	0.14	0.07	enet	37	0.07	8.9e-21	7.5	6.7	2.3e-11	0.74	0.96	0.04	FALSE
22	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	BMS1P4	0.05	0.01	enet	4	0.02	8.4e-03	8.6	-7.6	2.3e-14	-0.92	0.00	0.93	FALSE
23	The Cancer Genome Atlas	Breast Invasive Carcinoma	BMS1P4	0.03	0.03	lasso	4	0.03	2.2e-06	6.0	-5.5	4.0e-08	-0.69	0.59	0.36	FALSE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	CHCHD1	0.02	0.01	lasso	2	0.01	2.5e-03	8.6	8.6	1.0e-17	0.99	0.01	0.95	TRUE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	SEC24C	0.04	0.02	blup	29	0.03	2.6e-06	8.6	7.9	2.8e-15	0.89	0.01	0.99	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	FUT11	0.05	0.04	lasso	2	0.04	3.3e-05	5.6	-5.8	8.1e-09	-0.74	0.21	0.57	FALSE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	BMS1P4	0.03	0.01	blup	23	0.01	1.1e-02	5.6	-6.1	1.3e-09	-0.78	0.01	0.40	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	SEC24C	0.02	0.01	enet	4	0.01	8.5e-03	-2.8	5.2	2.0e-07	0.50	0.05	0.15	FALSE
29	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	BMS1P4	0.21	0.08	enet	15	0.08	2.3e-03	8.6	-7.7	9.2e-15	-0.88	0.00	0.82	FALSE