Best TWAS P=3.68e-10 · Best GWAS P=1.15e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OBFC1 | 0.12 | 0.04 | lasso | 3 | 0.05 | 8.4e-07 | -6.0 | 5.8 | 8.0e-09 | -0.91 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | OBFC1 | 0.14 | 0.07 | lasso | 4 | 0.06 | 4.9e-05 | -6.0 | 6.0 | 1.9e-09 | -0.98 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Muscle Skeletal | OBFC1 | 0.08 | 0.02 | enet | 19 | 0.04 | 7.8e-05 | -5.1 | -5.6 | 2.3e-08 | 0.70 | 0.02 | 0.92 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | RP11-541N10.3 | 0.09 | 0.06 | enet | 10 | 0.06 | 1.6e-08 | -6.0 | 6.3 | 3.7e-10 | -0.96 | 0.01 | 0.99 | TRUE |