[Hub]/) : Traits : Lung FVC : ← →

chr12:30,084,002-31,526,510

Best TWAS P=2.97e-12 · Best GWAS P=3.68e-14 conditioned to 0.00193

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous IPO8 0.13 0.09 lasso 6 0.12 2.7e-10 5.0 -6.4 1.7e-10 0.67 0.78 0.22 FALSE
2 GTEx Cells EBV-transformed lymphocytes IPO8 0.22 0.14 lasso 4 0.14 2.5e-05 -7.1 -6.2 5.6e-10 0.67 0.18 0.80 FALSE
3 GTEx Esophagus Muscularis IPO8 0.24 0.19 lasso 6 0.18 5.7e-11 4.9 -5.4 5.7e-08 0.51 1.00 0.00 FALSE
4 GTEx Lung IPO8 0.07 0.06 lasso 5 0.07 7.5e-06 5.0 -7.0 3.2e-12 0.79 0.04 0.96 FALSE
5 GTEx Nerve Tibial IPO8 0.21 0.16 lasso 6 0.15 1.3e-10 -7.0 -7.0 3.0e-12 0.85 0.15 0.85 TRUE
6 GTEx Skin Sun Exposed Lower leg IPO8 0.23 0.08 lasso 10 0.13 1.1e-10 -7.1 -6.8 8.7e-12 0.74 0.19 0.81 FALSE
7 ROSMAP Brain Pre-frontal Cortex IPO8 0.21 0.23 lasso 12 0.22 8.0e-28 5.0 -5.4 7.3e-08 0.51 1.00 0.00 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma IPO8 0.05 0.03 lasso 3 0.03 1.3e-06 4.8 -5.7 1.5e-08 0.56 0.93 0.07 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma IPO8 0.06 0.04 blup 58 0.04 1.5e-05 4.9 -5.4 7.2e-08 0.52 0.80 0.17 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IPO8 0.04 0.03 blup 58 0.03 9.7e-05 5.0 -6.1 8.9e-10 0.61 0.49 0.26 FALSE
11 The Cancer Genome Atlas Pancreatic Adenocarcinoma IPO8 0.09 0.05 blup 64 0.03 2.9e-02 4.8 -5.3 1.1e-07 0.49 0.11 0.11 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma IPO8 0.04 0.04 enet 7 0.02 8.1e-03 4.8 -5.3 1.0e-07 0.53 0.16 0.29 FALSE