Best TWAS P=3.51e-10 · Best GWAS P=1.91e-11 conditioned to 7.21e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | WWOX | 0.34 | 0.07 | lasso | 9 | 0.17 | 9.2e-10 | -5.0 | 5.1 | 3.1e-07 | 0.03 | 0.83 | 0.12 | FALSE |
| 2 | GTEx | Artery Coronary | WWOX | 0.66 | 0.09 | enet | 6 | 0.08 | 9.8e-04 | 6.2 | 6.3 | 3.5e-10 | 0.03 | 0.09 | 0.81 | TRUE |
| 3 | GTEx | Heart Left Ventricle | WWOX | 0.35 | 0.01 | lasso | 8 | 0.03 | 1.4e-02 | -4.9 | 5.8 | 5.0e-09 | 0.06 | 0.50 | 0.08 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CLEC3A | 0.30 | 0.22 | lasso | 4 | 0.29 | 1.7e-30 | 4.7 | 5.3 | 1.2e-07 | 0.03 | 0.31 | 0.69 | FALSE |