Best TWAS P=1.52e-08 · Best GWAS P=1.44e-10 conditioned to 4.76e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PIEZO1 | 0.11 | 0.11 | lasso | 2 | 0.11 | 1.0e-08 | 5.2 | -5.6 | 2.7e-08 | 0.13 | 0.59 | 0.40 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | RP5-1142A6.9 | 0.08 | 0.07 | lasso | 4 | 0.06 | 2.6e-05 | 5.2 | -5.2 | 1.9e-07 | 0.10 | 0.63 | 0.31 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | RP5-1142A6.7 | 0.08 | 0.01 | lasso | 5 | 0.00 | 1.4e-01 | 5.1 | -5.5 | 4.2e-08 | 0.11 | 0.16 | 0.20 | FALSE |
| 4 | GTEx | Heart Atrial Appendage | SNAI3-AS1 | 0.25 | 0.04 | lasso | 8 | 0.10 | 3.1e-05 | -2.2 | 5.5 | 3.4e-08 | -0.47 | 0.03 | 0.90 | FALSE |
| 5 | GTEx | Uterus | SNAI3-AS1 | 0.47 | 0.00 | enet | 13 | 0.04 | 5.3e-02 | -2.2 | 5.6 | 1.9e-08 | -0.59 | 0.03 | 0.45 | FALSE |
| 6 | GTEx | Whole Blood | SNAI3-AS1 | 0.15 | 0.04 | enet | 21 | 0.10 | 6.7e-10 | 4.5 | 5.7 | 1.5e-08 | -0.56 | 0.05 | 0.94 | TRUE |