[Hub]/) : Traits : Lung FVC :

chr16:88,030,355-89,544,756

Best TWAS P=1.52e-08 · Best GWAS P=1.44e-10 conditioned to 4.76e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts PIEZO1 0.11 0.11 lasso 2 0.11 1.0e-08 5.2 -5.6 2.7e-08 0.13 0.59 0.40 TRUE
2 GTEx Cells Transformed fibroblasts RP5-1142A6.9 0.08 0.07 lasso 4 0.06 2.6e-05 5.2 -5.2 1.9e-07 0.10 0.63 0.31 FALSE
3 GTEx Cells Transformed fibroblasts RP5-1142A6.7 0.08 0.01 lasso 5 0.00 1.4e-01 5.1 -5.5 4.2e-08 0.11 0.16 0.20 FALSE
4 GTEx Heart Atrial Appendage SNAI3-AS1 0.25 0.04 lasso 8 0.10 3.1e-05 -2.2 5.5 3.4e-08 -0.47 0.03 0.90 FALSE
5 GTEx Uterus SNAI3-AS1 0.47 0.00 enet 13 0.04 5.3e-02 -2.2 5.6 1.9e-08 -0.59 0.03 0.45 FALSE
6 GTEx Whole Blood SNAI3-AS1 0.15 0.04 enet 21 0.10 6.7e-10 4.5 5.7 1.5e-08 -0.56 0.05 0.94 TRUE