Best TWAS P=7.75e-10 · Best GWAS P=1.41e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | PARK7 | 0.02 | 0.01 | lasso | 3 | 0.01 | 1.4e-05 | -5.8 | -5.9 | 3.3e-09 | 0.97 | 0.01 | 0.99 | FALSE |
| 2 | YFS | Blood | PARK7 | 0.08 | 0.11 | lasso | 6 | 0.11 | 4.4e-34 | -5.8 | -5.9 | 2.8e-09 | 0.94 | 0.02 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ERRFI1 | 0.01 | 0.01 | blup | 27 | 0.00 | 4.3e-02 | -5.8 | 6.0 | 2.6e-09 | -0.99 | 0.01 | 0.83 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PARK7 | 0.03 | 0.03 | enet | 3 | 0.02 | 1.3e-03 | -6.0 | -6.1 | 7.8e-10 | 0.96 | 0.00 | 0.94 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | PARK7 | 0.03 | 0.03 | lasso | 1 | 0.02 | 5.0e-03 | -5.8 | -5.8 | 5.7e-09 | 0.95 | 0.01 | 0.81 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PARK7 | 0.04 | 0.03 | blup | 36 | 0.03 | 4.9e-04 | -6.0 | -5.5 | 4.9e-08 | 0.88 | 0.01 | 0.96 | FALSE |