[Hub]/) : Traits : Lung FVC :

chr19:36,113,459-37,605,917

Best TWAS P=8.89e-11 · Best GWAS P=1.39e-08 conditioned to 0.428

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ZFP82 0.15 0.04 enet 9 0.10 4.8e-06 5.0 -5.2 2.6e-07 -0.75 0.02 0.97 FALSE
2 GTEx Artery Aorta LINC00665 0.20 0.10 lasso 7 0.10 2.8e-06 5.6 -5.4 7.3e-08 -0.87 0.01 0.99 FALSE
3 GTEx Cells Transformed fibroblasts LINC00665 0.18 0.08 lasso 8 0.12 1.7e-09 5.6 -5.2 2.3e-07 -0.73 0.01 0.99 FALSE
4 GTEx Esophagus Muscularis ZFP82 0.11 0.07 lasso 4 0.06 1.9e-04 5.6 -5.7 1.0e-08 -0.98 0.01 0.99 FALSE
5 GTEx Lung LINC00665 0.10 0.08 lasso 4 0.05 9.9e-05 5.6 -5.2 1.7e-07 -0.81 0.01 0.98 FALSE
6 GTEx Nerve Tibial ZFP14 0.08 0.00 lasso 7 0.00 4.8e-01 5.6 -5.6 2.2e-08 -0.94 0.01 0.93 FALSE
7 GTEx Nerve Tibial ZFP82 0.09 0.11 lasso 3 0.09 5.6e-07 5.6 -5.6 2.7e-08 -0.88 0.01 0.99 FALSE
8 GTEx Testis ZFP82 0.28 0.14 lasso 5 0.11 1.3e-05 5.0 -5.6 2.8e-08 -0.85 0.04 0.96 FALSE
9 YFS Blood ZFP14 0.37 0.43 bslmm 301 0.44 1.2e-160 5.6 5.2 2.1e-07 0.85 0.01 0.99 FALSE
10 YFS Blood ZFP82 0.23 0.24 bslmm 300 0.25 4.0e-81 5.0 -5.7 1.5e-08 -0.82 0.09 0.91 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma ZFP14 0.09 0.08 lasso 2 0.07 8.1e-07 5.3 -5.3 9.0e-08 -0.87 0.00 1.00 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ZFP14 0.06 0.03 lasso 2 0.03 4.5e-04 5.6 -5.6 2.4e-08 -0.89 0.00 0.97 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ZFP82 0.06 0.02 blup 31 0.02 8.5e-04 5.3 -6.0 1.8e-09 -0.82 0.00 0.93 FALSE
14 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ZFP82 0.13 0.07 lasso 1 0.05 5.0e-04 5.3 -5.3 9.0e-08 -0.87 0.00 0.99 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma ZFP82 0.06 0.01 lasso 2 0.02 6.5e-04 5.3 -5.7 1.0e-08 -0.82 0.00 0.94 FALSE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ZNF565 0.08 0.04 blup 48 0.04 3.8e-05 5.6 5.9 4.2e-09 0.90 0.00 0.99 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma ZFP14 0.13 0.09 lasso 2 0.09 1.3e-09 5.3 -5.3 9.1e-08 -0.87 0.00 1.00 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma ZFP82 0.08 0.02 blup 31 0.03 5.4e-04 -3.9 -5.3 1.3e-07 -0.61 0.01 0.68 FALSE
19 The Cancer Genome Atlas Prostate Adenocarcinoma ZNF565 0.05 0.01 blup 47 0.03 8.8e-04 -3.2 5.5 3.5e-08 0.75 0.01 0.92 FALSE
20 The Cancer Genome Atlas Testicular Germ Cell Tumors ZFP14 0.22 0.08 enet 8 0.13 2.4e-05 5.0 -6.5 8.9e-11 -0.80 0.00 0.78 TRUE
21 The Cancer Genome Atlas Thyroid Carcinoma ZFP82 0.11 0.03 enet 6 0.04 4.7e-05 5.0 -5.9 3.5e-09 -0.73 0.01 0.97 FALSE