Best TWAS P=3.27e-23 · Best GWAS P=1.09e-22 conditioned to 0.0401
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | BLVRB | 0.04 | 0.00 | bslmm | 378 | 0.01 | 1.8e-02 | -1.3 | -5.2 | 2.4e-07 | -0.25 | 0.17 | 0.12 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | LTBP4 | 0.09 | 0.05 | lasso | 9 | 0.04 | 3.9e-06 | 9.8 | -9.9 | 3.3e-23 | -0.90 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Brain Cerebellar Hemisphere | LTBP4 | 0.62 | 0.22 | enet | 29 | 0.47 | 1.3e-13 | 9.5 | 8.0 | 1.8e-15 | 0.69 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Lung | SHKBP1 | 0.12 | 0.12 | enet | 20 | 0.09 | 1.8e-07 | 9.8 | 8.9 | 5.3e-19 | 0.89 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Whole Blood | SHKBP1 | 0.12 | 0.09 | lasso | 3 | 0.07 | 3.7e-07 | 9.8 | 9.8 | 9.8e-23 | 1.00 | 0.01 | 0.99 | FALSE |
| 6 | NTR | Blood | SHKBP1 | 0.05 | 0.04 | enet | 18 | 0.04 | 3.1e-13 | 9.8 | 9.5 | 2.3e-21 | 0.88 | 0.01 | 0.99 | FALSE |
| 7 | YFS | Blood | SHKBP1 | 0.51 | 0.09 | enet | 92 | 0.27 | 1.6e-88 | 9.7 | 6.7 | 2.7e-11 | 0.63 | 0.02 | 0.98 | FALSE |
| 8 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LTBP4 | 0.01 | 0.00 | blup | 54 | 0.01 | 2.0e-02 | 6.5 | -8.5 | 1.2e-17 | -0.77 | 0.02 | 0.53 | FALSE |