[Hub]/) : Traits : Lung FVC :

chr2:23,453,834-25,083,310

Best TWAS P=2.21e-14 · Best GWAS P=7.64e-14 conditioned to 0.147

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous UBXN2A 0.06 0.04 lasso 5 0.04 5.2e-04 -7.4 -7.4 1.8e-13 0.95 0.01 0.99 FALSE
2 GTEx Adipose Visceral Omentum UBXN2A 0.10 0.08 enet 29 0.03 9.8e-03 -6.2 -6.5 1.1e-10 0.69 0.03 0.96 FALSE
3 GTEx Artery Aorta UBXN2A 0.20 0.09 lasso 6 0.08 4.1e-05 -5.3 -6.2 6.8e-10 0.70 0.37 0.62 FALSE
4 GTEx Artery Tibial UBXN2A 0.12 0.06 enet 24 0.09 1.5e-07 -5.3 -7.1 1.4e-12 0.84 0.03 0.97 FALSE
5 GTEx Cells Transformed fibroblasts UBXN2A 0.12 0.07 enet 12 0.12 4.7e-09 -6.9 -6.0 2.3e-09 0.75 0.04 0.96 FALSE
6 GTEx Colon Transverse UBXN2A 0.11 0.01 enet 8 0.03 8.7e-03 -7.4 -7.5 6.4e-14 0.93 0.01 0.94 FALSE
7 GTEx Esophagus Mucosa UBXN2A 0.12 0.06 lasso 6 0.05 1.9e-04 -5.6 -5.3 1.4e-07 0.57 0.67 0.08 FALSE
8 GTEx Esophagus Muscularis UBXN2A 0.08 0.07 lasso 6 0.06 2.4e-04 -5.6 -5.5 3.3e-08 0.58 0.61 0.07 FALSE
9 GTEx Lung UBXN2A 0.09 0.06 enet 7 0.07 6.1e-06 -5.6 -7.4 1.7e-13 0.88 0.02 0.98 FALSE
10 GTEx Muscle Skeletal UBXN2A 0.10 0.04 lasso 7 0.03 5.5e-04 -5.6 -6.6 3.5e-11 0.73 0.15 0.85 FALSE
11 GTEx Prostate FAM228B 0.16 0.02 enet 31 0.07 9.6e-03 -6.1 5.9 2.9e-09 -0.74 0.11 0.36 FALSE
12 GTEx Skin Sun Exposed Lower leg UBXN2A 0.08 0.04 enet 17 0.03 1.3e-03 -7.5 -7.6 2.2e-14 0.89 0.01 0.99 TRUE
13 GTEx Small Intestine Terminal Ileum UBXN2A 0.18 0.08 enet 33 0.16 2.5e-04 -6.1 -6.1 9.0e-10 0.78 0.04 0.85 FALSE
14 GTEx Spleen UBXN2A 0.31 0.11 enet 19 0.17 4.1e-05 6.4 -7.1 1.3e-12 0.72 0.06 0.88 FALSE
15 GTEx Stomach UBXN2A 0.13 0.14 enet 5 0.14 3.6e-07 -5.3 -6.7 1.9e-11 0.80 0.07 0.92 FALSE
16 GTEx Whole Blood UBXN2A 0.17 0.07 lasso 8 0.09 2.1e-08 -5.6 -7.5 4.8e-14 0.83 0.02 0.98 FALSE
17 The Cancer Genome Atlas Lung Squamous Cell Carcinoma UBXN2A 0.03 0.02 blup 46 0.03 5.7e-04 -5.7 -6.4 1.8e-10 0.68 0.17 0.60 FALSE