Best TWAS P=1.6e-13 · Best GWAS P=2.29e-13 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | AC062029.1 | 0.14 | 0.10 | enet | 11 | 0.12 | 1.3e-09 | -6.5 | -6.9 | 4.2e-12 | 0.94 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | AC062029.1 | 0.07 | 0.08 | lasso | 3 | 0.07 | 3.0e-06 | -7.3 | -7.4 | 1.6e-13 | 0.98 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Nerve Tibial | RPIA | 0.10 | 0.03 | lasso | 10 | 0.04 | 1.3e-03 | -6.5 | -6.4 | 1.4e-10 | 0.80 | 0.05 | 0.35 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | RPIA | 0.05 | 0.05 | blup | 194 | 0.04 | 4.3e-06 | -6.0 | -6.0 | 2.1e-09 | 0.69 | 0.01 | 0.99 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | EIF2AK3 | 0.11 | 0.09 | lasso | 5 | 0.09 | 2.0e-11 | -7.3 | -7.0 | 2.4e-12 | 0.97 | 0.00 | 1.00 | FALSE |