[Hub]/) : Traits : Lung FVC : ← →

chr2:68,850,921-71,228,388

Best TWAS P=8.43e-16 · Best GWAS P=6.23e-18 conditioned to 2.34e-06

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	NFU1	0.13	0.08	lasso	6	0.15	5.3e-08	-2.8	-5.9	3.6e-09	0.59	0.18	0.80	FALSE
2	GTEx	Adrenal Gland	NFU1	0.23	0.15	lasso	23	0.19	2.9e-07	6.6	-7.1	1.0e-12	0.45	0.94	0.02	FALSE
3	GTEx	Artery Tibial	GFPT1	0.09	0.05	lasso	4	0.02	1.1e-02	6.8	-6.7	2.4e-11	0.33	0.87	0.01	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	FAM136A	0.31	0.12	lasso	7	0.16	5.6e-06	4.9	5.6	2.1e-08	0.01	0.02	0.97	FALSE
5	GTEx	Cells Transformed fibroblasts	AAK1	0.08	0.05	lasso	5	0.03	1.4e-03	6.6	6.2	4.1e-10	-0.30	0.85	0.01	FALSE
6	GTEx	Cells Transformed fibroblasts	C2orf42	0.18	0.05	enet	28	0.14	1.3e-10	-4.4	5.4	5.3e-08	-0.05	0.05	0.93	FALSE
7	GTEx	Colon Transverse	AAK1	0.07	0.07	lasso	2	0.05	2.1e-03	5.2	6.4	1.5e-10	-0.38	0.38	0.04	FALSE
8	GTEx	Lung	AAK1	0.05	0.00	lasso	5	0.01	2.7e-02	5.2	5.3	1.1e-07	-0.39	0.12	0.27	FALSE
9	GTEx	Muscle Skeletal	GFPT1	0.08	0.00	lasso	8	0.00	2.2e-01	6.6	-7.6	2.4e-14	0.59	0.13	0.81	FALSE
10	GTEx	Nerve Tibial	GFPT1	0.13	0.01	lasso	4	0.02	1.8e-02	6.6	-6.8	1.1e-11	0.37	0.26	0.04	FALSE
11	GTEx	Spleen	GFPT1	0.20	0.09	enet	13	0.08	4.7e-03	6.5	-7.7	2.0e-14	0.44	0.33	0.23	FALSE
12	GTEx	Thyroid	NFU1	0.12	0.09	lasso	8	0.06	2.6e-05	-6.7	-6.4	1.3e-10	0.54	0.99	0.00	FALSE
13	GTEx	Whole Blood	GFPT1	0.06	0.00	enet	7	0.00	2.6e-01	5.2	-5.5	3.3e-08	0.41	0.14	0.31	FALSE
14	METSIM	Adipose	NFU1	0.04	0.02	blup	426	0.03	1.6e-05	-6.6	-6.5	6.4e-11	0.50	0.86	0.05	FALSE
15	NTR	Blood	GFPT1	0.01	0.01	blup	450	0.01	5.2e-04	6.6	-5.4	7.6e-08	0.50	0.76	0.07	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	SNRPG	0.03	0.01	blup	225	0.02	2.7e-03	4.9	5.7	1.3e-08	-0.01	0.02	0.89	FALSE
17	YFS	Blood	GFPT1	0.10	0.23	lasso	24	0.24	1.3e-75	-6.7	-6.5	5.8e-11	0.55	1.00	0.00	FALSE
18	YFS	Blood	NFU1	0.08	0.04	blup	420	0.07	1.8e-22	-6.6	-5.2	1.6e-07	0.42	1.00	0.00	FALSE
19	The Cancer Genome Atlas	Glioblastoma Multiforme	GFPT1	0.07	0.09	blup	67	0.08	2.5e-03	-6.8	-8.1	8.4e-16	0.64	0.06	0.54	TRUE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GFPT1	0.05	0.03	blup	67	0.04	2.0e-05	6.7	-6.0	2.0e-09	0.37	0.88	0.01	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GFPT1	0.05	0.00	blup	67	0.02	5.9e-03	6.6	-5.3	1.4e-07	0.18	0.04	0.04	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	FAM136A	0.02	0.01	blup	42	0.01	2.1e-02	-4.9	5.2	2.0e-07	-0.01	0.00	0.48	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	GFPT1	0.12	0.05	blup	67	0.04	3.9e-05	6.5	-5.2	1.7e-07	0.20	0.89	0.01	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C2orf42	0.05	0.00	blup	46	0.03	4.9e-04	-4.4	5.2	1.7e-07	-0.01	0.02	0.66	FALSE
25	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FAM136A	0.06	0.01	enet	5	0.00	1.7e-01	-4.9	5.2	2.7e-07	-0.02	0.00	0.65	FALSE
26	The Cancer Genome Atlas	Soft Tissue Sarcoma	C2orf42	0.12	0.03	enet	17	0.05	1.0e-03	-5.1	6.5	6.2e-11	0.02	0.00	0.82	TRUE
27	The Cancer Genome Atlas	Skin Cutaneous Melanoma	GFPT1	0.11	0.07	blup	67	0.06	1.1e-02	-6.7	-7.2	5.5e-13	0.61	0.13	0.46	FALSE
28	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	GFPT1	0.12	0.02	blup	67	0.09	2.0e-03	-6.8	-7.5	5.5e-14	0.54	0.16	0.15	FALSE