Best TWAS P=3.1e-10 · Best GWAS P=2.3e-11 conditioned to 0.0233
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | AFF1 | 0.10 | 0.06 | lasso | 5 | 0.06 | 2.4e-05 | -6.7 | -6.3 | 3.1e-10 | 0.94 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | KLHL8 | 0.07 | 0.01 | lasso | 5 | 0.02 | 2.1e-02 | -3.6 | -5.3 | 1.1e-07 | 0.68 | 0.34 | 0.50 | FALSE |