Best TWAS P=9.65e-09 · Best GWAS P=2.12e-11 conditioned to 0.000115
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | RP1-244F24.1 | 0.12 | 0.00 | enet | 11 | 0.02 | 1.0e-02 | -6.0 | 5.7 | 9.7e-09 | -0.70 | 0.06 | 0.73 | TRUE |
| 2 | GTEx | Pituitary | SUPT3H | 0.26 | 0.08 | lasso | 6 | 0.05 | 1.8e-02 | 4.7 | 5.2 | 1.6e-07 | 0.01 | 0.11 | 0.05 | TRUE |
| 3 | YFS | Blood | SUPT3H | 0.06 | 0.09 | lasso | 13 | 0.12 | 2.2e-36 | -4.0 | 5.2 | 2.4e-07 | 0.03 | 0.95 | 0.05 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SUPT3H | 0.07 | 0.05 | enet | 12 | 0.08 | 1.1e-09 | 4.7 | 5.1 | 2.8e-07 | 0.02 | 0.52 | 0.48 | FALSE |