Best TWAS P=9.27e-09 · Best GWAS P=2.83e-07 conditioned to 0.363
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | PIGV | 0.10 | 0.14 | lasso | 10 | 0.10 | 7.6e-06 | -5.1 | 5.2 | 2.3e-07 | -1.00 | 0.05 | 0.94 | FALSE |
| 2 | GTEx | Thyroid | ZDHHC18 | 0.11 | 0.10 | lasso | 4 | 0.13 | 4.2e-10 | -5.1 | -5.4 | 7.6e-08 | 0.81 | 0.04 | 0.96 | FALSE |
| 3 | METSIM | Adipose | ZDHHC18 | 0.04 | 0.03 | lasso | 2 | 0.04 | 3.8e-06 | -5.0 | -5.7 | 9.3e-09 | 0.80 | 0.07 | 0.92 | TRUE |
| 4 | NTR | Blood | ARID1A | 0.03 | 0.03 | enet | 20 | 0.03 | 7.8e-11 | -4.9 | 5.5 | 3.2e-08 | -0.92 | 0.07 | 0.92 | FALSE |
| 5 | YFS | Blood | ZDHHC18 | 0.08 | 0.11 | bslmm | 286 | 0.11 | 2.1e-33 | -5.1 | -5.4 | 6.0e-08 | 0.80 | 0.03 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PIGV | 0.02 | 0.02 | lasso | 10 | 0.03 | 1.3e-06 | -5.3 | 5.5 | 3.2e-08 | -0.88 | 0.01 | 0.98 | FALSE |
| 7 | The Cancer Genome Atlas | Colon Adenocarcinoma | PIGV | 0.05 | 0.03 | blup | 19 | 0.02 | 2.0e-02 | -5.3 | 5.4 | 6.1e-08 | -0.87 | 0.00 | 0.68 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PIGV | 0.03 | 0.05 | lasso | 7 | 0.04 | 4.2e-05 | -4.9 | 5.2 | 1.9e-07 | -0.95 | 0.03 | 0.96 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | PIGV | 0.04 | 0.04 | lasso | 4 | 0.04 | 2.1e-04 | -5.2 | 5.2 | 1.6e-07 | -0.66 | 0.00 | 0.97 | FALSE |