TWAS hub - ARID1A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Whole Blood	0.0730	0.0340	4.4e-03	0.003	NA	0.033	NA	0.021	1.7e-01	NA	4.4e-04	NA	4.4e-03
2	NTR	Blood	0.0284	0.0091	1.6e-08	0.033	0.029	0.033	0.031	0.032	6.7e-11	1.2e-09	7.8e-11	2.6e-10	1.4e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
High cholesterol (Self-reported)	10.9	19.3	37.2	-1.2	-6.1
Cholesterol lowering medication	10.7	15.8	29.5	-1.4	-5.4
HDL Cholesterol	9.7	16.3	30.6	1.4	5.5
Medication: Bendroflumethiazide	9.1	13.9	17.6	-3.2	-4.2
Cardiovascular Disease	9.0	29.8	50.1	-3.1	-7.1
Medication: Blood pressure	8.1	15.5	17.1	-3.7	-4.1
Qualifications: O levels/GCSEs or equivalent	7.7	12.3	14.3	-3.2	-3.8
Medication: Atorvastatin	7.7	9.5	15.8	-1.8	-4.0
LDL Cholesterol	7.5	11.8	22.9	-0.8	-4.8
Medication: Simvastatin	6.9	10.1	19.0	-1.1	-4.4
Hypertension (Self-reported)	6.9	19.1	20.4	-4.2	-4.5
High blood pressure (mother)	6.8	9.6	18.1	-1.1	-4.2
High blood pressure	6.7	18.8	21.4	-4.0	-4.6
Medication for cholesterol	6.5	9.9	12.6	2.7	3.5
Deep venous thrombosis (DVT) (self-reported)	6.3	8.2	16.2	0.3	4.0
Blood Platelet Count	6.1	70.9	108.2	-5.8	-10.4
Blood clot in the leg (DVT)	6.1	7.8	15.5	0.4	3.9
Medication: Allopurinol	6.1	8.1	14.2	-1.4	-3.8
Vascular/heart problems diagnosed by doctor	5.8	15.7	17.2	3.8	4.2
Angina	5.5	7.2	7.7	-2.6	-2.8
Angina (self-reported)	5.4	7.2	9.3	-2.2	-3.1
Systolic Blood Pressure	5.2	26.0	45.6	-2.5	-6.8
Number of treatments/medications taken	5.2	9.3	9.6	-3.0	-3.1
Relative age of first facial hair	5.1	10.5	13.6	-2.7	-3.7
Medication: Cholesterol lowering	5.1	8.0	15.2	-0.8	-3.9
Diastolic blood pressure, automated reading	5.1	15.8	16.3	-4.0	-3.9
Alcohol intake versus 10 years previously	4.9	7.3	14.4	-3.8	-0.3
Systolic blood pressure, automated reading	4.8	13.9	17.8	-3.2	-4.2
Alcohol drinker status: Previous	4.8	5.5	7.0	-2.6	-2.0
Gout (self-reported)	4.7	6.4	11.0	-1.3	-3.3
Qualifications: NVQ or HND or HNC or equivalent	4.6	5.5	9.9	-3.1	-1.1
High blood pressure (siblings)	4.2	6.1	8.7	-1.8	-3.0
Medication for cholesterol, blood pressure or diabetes	3.9	6.4	9.4	1.9	3.1
Age at First Birth	3.8	5.5	6.8	2.6	2.0
Triglycerides	3.7	6.1	12.0	-0.5	-3.5
Medication: Co-codamol	3.7	4.2	8.2	0.5	2.9
Illnesses of siblings	3.6	5.1	8.7	1.2	3.0
Medication: Aspirin	3.5	4.7	5.2	-2.0	-2.3
Qualifications: nursing, teaching	3.5	5.4	7.5	-1.8	-2.7
Medication: Aspirin	3.5	4.6	5.0	-2.2	-2.0
Shortness of breath walking on level ground	3.3	3.9	4.0	-1.9	-2.0
Ever smoked	3.3	5.7	11.5	-3.4	-0.0
Medication: Lisinopril	3.1	4.1	7.3	-0.9	-2.7
Crohns Disease (2017)	2.8	6.2	11.4	3.4	-0.9
Blood Eosinophil Count	2.8	21.6	42.1	-1.0	-6.5
Medication: Atenolol	2.8	3.4	5.6	-1.1	-2.4
Number of full sisters	2.8	3.4	6.9	-2.6	0.1
Osteoporosis (self-reported)	2.8	3.4	6.1	2.5	0.9
Neck or shoulder pain in last month	2.6	3.7	6.1	-1.1	2.5
Irritability	2.6	4.4	8.6	-0.5	2.9
Schizophrenia (2018)	2.5	5.1	7.8	1.6	2.8
Worry (Nagel 2018)	2.5	5.4	7.6	-1.8	-2.8
Qualifications: None of the above	2.5	5.3	6.6	2.0	2.6
Father’s age at death	2.5	3.4	6.8	0.1	2.6
Qualifications: A levels/AS levels or equivalent	2.5	5.4	8.9	-1.4	-3.0
HbA1C	2.4	2.6	5.2	0.1	2.3
Heel T-Score	2.4	19.1	35.2	-5.9	-1.7
Hypothyroidism/myxoedema (self-reported)	2.4	4.6	8.5	-2.9	-0.9
Diabetes diagnosed by doctor	2.4	4.0	6.9	-1.1	-2.6
Fluid intelligence score	2.3	4.8	5.9	-1.9	-2.4
Suffer from ‘nerves’	2.3	3.6	4.4	-2.1	-1.7
Verbal and Numeric Reasoning (VNR)	2.2	5.3	6.1	-2.1	-2.5
Schizophrenia (2014)	2.2	4.9	7.1	1.6	2.7
Height	2.2	42.8	69.6	-4.0	-8.3
Illnesses of mother	2.2	2.8	5.5	-0.1	2.4
Comparative height size at age 10	2.2	12.3	16.9	-2.8	-4.1
Exposure to tobacco smoke at home	2.1	2.3	2.9	-1.7	1.3
Had major operations	2.1	2.5	4.4	-0.8	-2.1
Pack years of smoking	2.1	3.1	5.3	-2.3	-0.9
Intelligence (Savage-Jansen 2018)	2.0	6.0	10.4	-1.3	-3.2
Medication: Blood pressure	2.0	3.6	4.7	-1.6	-2.2
Smoking status: Previous	2.0	3.0	6.0	-0.2	2.4
Ever taken oral contraceptive pill	2.0	2.3	3.6	-1.0	1.9
Bipolar Disorder or Schizophrenia	1.9	4.7	7.8	1.3	2.8
Ulcerative Colitis	1.9	2.8	4.3	-1.1	-2.1
Nervous feelings	1.9	3.6	6.2	-1.0	-2.5
Friendships satisfaction	1.9	2.3	4.1	0.7	2.0
Ever had prostate specific antigen (PSA) test	1.9	2.2	4.2	0.3	2.1
Body Mass Index (BMI) (2010)	1.8	2.4	3.0	1.4	1.7
Supplements: Zinc	1.8	2.0	3.2	-1.8	-0.8
Loud music exposure frequency	1.8	2.0	3.1	-1.8	-0.9
Illnesses of siblings: Diabetes	1.8	2.3	2.4	-1.6	-1.4
Crohns Disease (2012)	1.7	2.7	4.7	2.2	-0.8
Lupus	1.7	2.6	3.1	-1.5	-1.8
Medication: Levothyroxine sodium	1.7	2.8	5.3	-2.3	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	1.7	3.8	4.6	-2.1	1.8
Diabetes (self-reported)	1.7	2.6	5.1	-0.5	-2.2
Mean time to correctly identify matches	1.7	3.2	6.4	-0.4	2.5
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.5	5.1	1.4	-2.3
Back pain experienced in last month	1.7	2.5	4.8	0.4	2.2
Fractured/broken bones in last 5 years	1.7	2.2	3.6	1.9	1.0
Reaction Time	1.6	3.0	5.9	0.2	2.4
Ever used hormone-replacement therapy (HRT)	1.6	2.0	2.0	-1.4	1.4
Commuting to job workplace: Car/motor vehicle	1.6	1.9	3.4	1.9	0.5
Hypothyroidism (self reported)	1.5	3.5	4.6	-2.1	-1.6
Type 2 Diabetes (T2D) (2018)	1.5	2.8	5.1	-0.7	-2.3
Standing height	1.5	14.8	25.8	-2.0	-5.1
Number of full brothers	1.5	1.9	1.9	-1.4	-1.4
Osteoarthritis (self-reported)	1.5	2.0	3.1	0.9	1.8
Hearing aid user	1.5	1.7	2.9	-0.8	-1.7
Pain type(s) experienced in last month: Hip pain	1.5	1.8	3.5	-1.9	0.5
Pain experienced in last month	1.5	2.5	2.7	1.6	-1.5
Pack years adult smoking proportion	1.4	2.2	3.5	-1.9	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.1	5.0	-2.2	1.1
Chest pain or discomfort	1.4	2.1	2.3	-1.4	-1.5
Smoking status: Current	1.4	2.2	2.8	-1.7	-1.2
Number of self-reported non-cancer illnesses	1.4	2.4	2.6	-1.5	-1.6
Hand grip strength (right)	1.3	3.6	3.6	-1.9	-1.9
Current tobacco smoking	1.3	2.2	3.1	-1.8	-1.1
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	2.2	-1.5	-0.9
Ever highly irritable/argumentative for 2 days	1.3	1.5	3.0	-1.7	0.1
Chronic bronchitis/emphysema (mother)	1.3	1.5	2.1	1.5	-0.9
Mouth/teeth dental problems: Loose teeth	1.3	1.5	2.3	-1.5	-0.9
Age at last live birth	1.3	1.8	3.1	0.8	1.8
Commuting to job workplace: Walk	1.3	1.4	2.5	-1.6	0.4
Risk taking	1.3	1.9	3.8	-2.0	-0.1
Alzheimer’s Disease (in father)	1.2	1.3	2.2	-0.5	1.5
Hand grip strength (left)	1.2	3.2	4.0	-1.6	-2.0
Maternal smoking around birth	1.2	1.7	2.3	1.0	1.5
Worrier / anxious feelings	1.2	2.2	3.7	-0.8	-1.9
Noisy workplace	1.2	1.5	2.9	-1.7	-0.3
Pulse wave reflection index	1.2	1.5	2.2	-0.9	-1.5
Health satisfaction	1.2	1.6	2.5	-0.8	1.6
Ever depressed for a whole week	1.2	1.5	2.2	-1.5	-0.9
Irritable Bowel Disease (IBD)	1.1	2.6	3.5	1.9	-1.3
Blood White Count	1.1	7.9	13.8	3.7	1.4
Allergy or Eczema	1.1	2.8	5.0	2.2	-0.8
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	1.5	1.1	1.2
Past tobacco smoking	1.1	2.1	2.9	1.7	-1.1
Hair/balding pattern: Pattern 2	1.1	1.4	1.6	1.1	1.3
Breastfed as a baby	1.1	1.4	2.7	0.3	1.6
Tense / ‘highly strung’	1.1	1.9	2.8	-1.0	-1.7
Medication for pain relief, constipation, heartburn	1.1	1.9	3.5	1.9	0.6
Handedness (chirality/laterality): Left-handed	1.1	1.4	2.4	0.6	1.5
Eye problems/disorders: Cataract	1.1	1.3	2.1	1.5	-0.7
Alzheimer’s Disease (including proxy)	1.0	1.5	2.4	0.8	1.6
Breast Cancer	1.0	2.4	2.8	1.4	1.7
Hearing difficulty/problems: Yes	1.0	1.5	2.9	-1.7	-0.4
Sitting height	1.0	7.4	9.2	-2.3	-3.0
Ever unenthusiastic/disinterested for a whole week	1.0	1.3	2.1	-1.4	-0.7
Mouth/teeth dental problems	1.0	1.5	2.8	1.7	-0.5
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	2.6	1.6	-0.1
Medication: Ramipril	1.0	1.2	2.5	-0.1	-1.6
Glaucoma (self-reported)	1.0	1.2	1.5	-0.9	1.2
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	2.3	0.2	1.5
Mouth/teeth dental problems: Mouth ulcers	1.0	1.5	1.7	-1.2	1.3
Average weekly champagne plus white wine intake	1.0	1.4	1.6	-1.0	-1.3
Prostate Cancer	0.9	1.2	1.4	1.2	1.0
Hair Pigment	0.9	24.3	42.5	-2.5	-6.5
Serious illness, injury or assault to yourself	0.9	1.1	1.9	0.6	1.4
Number of incorrect matches in round	0.9	1.4	2.0	0.9	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	2.8	-1.7	-0.1
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	1.8	-1.3	0.7
Medication: Ventolin 100micrograms inhaler	0.9	1.1	2.2	1.5	0.2
Leg pain on walking	0.9	1.1	1.9	-1.4	-0.6
Knee pain experienced in last month	0.9	1.4	2.8	-0.3	1.7
Alzheimer’s Disease (in mother)	0.8	1.0	1.3	0.8	1.1
Coronary Artery Disease (CAD)	0.8	1.0	2.0	-0.0	-1.4
Medication: Metformin	0.8	1.2	1.2	-1.1	-1.1
Pulse wave Arterial Stiffness index	0.8	0.9	1.0	-0.9	-1.0
Medication: Amlodipine	0.8	1.1	2.0	-1.4	-0.6
Medication: Ibuprofen	0.8	1.0	2.0	-1.4	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	3.1	0.2	1.8
Wears glasses or contact lenses	0.8	0.9	0.9	-0.9	-1.0
Unable to work because of sickness or disability	0.8	1.0	2.0	-0.2	1.4
Heart disease (siblings)	0.8	1.0	1.6	-0.6	-1.2
Arm predicted mass (left)	0.8	4.2	6.6	-2.6	-1.3
Major Depression (MDD)	0.7	0.9	1.4	-1.2	-0.6
Bipolar Disorder (2011)	0.7	0.6	1.3	-0.1	1.1
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.0	1.0	0.8
Chronotype (morning person)	0.7	1.7	3.1	-0.6	1.8
Frequency of depressed mood in last 2 weeks	0.7	0.9	1.2	-1.1	-0.8
Townsend deprivation index at recruitment	0.7	0.9	1.5	0.6	1.2
Relative age voice broke	0.7	1.0	1.2	-1.1	-0.9
Hayfever, allergic rhinitis or eczema	0.7	1.5	2.9	1.7	-0.4
Chronic bronchitis/emphysema (father)	0.7	0.8	1.6	-0.2	-1.3
Hearing difficulty/problems with background noise	0.7	1.2	1.5	-0.9	1.2
Neuroticism score	0.7	1.5	1.7	-1.3	-1.2
Migraine (self-reported)	0.7	0.8	1.6	-1.3	-0.2
Supplements: Vitamin C	0.7	0.8	1.4	-0.5	1.2
Guilty feelings	0.7	1.0	1.3	-1.1	-0.9
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.7	-1.3	0.1
Arm fat-free mass (left)	0.7	3.4	5.7	-2.4	-1.1
Lung FVC	0.6	3.3	6.5	0.1	2.6
Tanning	0.6	6.9	9.1	-2.2	3.0
Sensitivity / hurt feelings	0.6	1.1	2.2	-0.0	-1.5
Diabetes (father)	0.6	0.8	1.1	-1.1	-0.6
Diabetes (mother)	0.6	0.7	1.4	-1.2	0.2
Impedance of leg (left)	0.6	3.0	5.4	0.8	-2.3
Alcohol usually taken with meals	0.6	0.9	1.1	0.8	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	1.6	-1.3	-0.5
Weight	0.6	2.8	4.3	-2.1	-1.1
Trunk fat-free mass	0.6	3.5	4.6	-2.1	-1.6
Falls in the last year	0.6	0.8	1.5	-0.1	1.2
Trunk predicted mass	0.6	3.3	4.5	-2.1	-1.4
Length of working week for main job	0.6	0.7	0.8	-0.8	-0.9
Peak expiratory flow (PEF)	0.6	1.3	1.7	-0.9	1.3
Arm fat-free mass (right)	0.6	3.0	4.9	-2.2	-1.0
Comparative body size at age 10	0.6	1.8	2.7	-1.6	0.9
Worry too long after embarrassment	0.6	1.0	1.4	1.2	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	1.4	-0.2	1.2
Eye problems/disorders: None of the above	0.6	0.7	1.4	-1.2	-0.2
Arm predicted mass (right)	0.6	3.0	4.7	-2.2	-1.2
Commuting to job workplace: Cycle	0.6	0.8	1.4	-0.4	-1.2
Ovarian Cancer	0.5	0.7	1.2	1.1	0.3
Smoking Status	0.5	1.2	2.4	-1.6	0.2
Average weekly spirits intake	0.5	0.6	0.9	0.5	1.0
Medication for hormone replacement therapy	0.5	0.6	0.9	-1.0	0.5
Severe depression (siblings)	0.5	0.5	0.8	-0.9	0.5
Impedance of leg (right)	0.5	2.3	3.6	1.0	-1.9
Trunk fat mass	0.5	2.1	3.0	-1.7	-1.1
Had menopause	0.5	0.7	0.8	-0.9	0.8
Pain all over the body in last month	0.5	0.6	0.7	0.8	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.1	-0.5	1.0
Impedance of arm (left)	0.5	2.2	2.5	1.6	-1.4
Number of children fathered	0.5	0.6	1.1	-1.1	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.0	-0.4	1.0
Overall health rating	0.5	1.2	2.1	-1.4	0.5
Whole body fat-free mass	0.5	2.8	4.3	-2.1	-1.1
Mood swings	0.5	0.9	1.5	-0.6	1.2
Loneliness, isolation	0.5	0.7	1.3	-1.1	-0.5
Whole body water mass	0.5	2.7	4.2	-2.0	-1.1
Eye problems/disorders: Glaucoma	0.5	0.6	1.1	-0.2	1.1
Basal metabolic rate	0.5	2.8	4.4	-2.1	-1.1
Number of operations (self-reported)	0.5	0.8	1.0	-1.0	-0.8
Supplements: Calcium	0.5	0.5	1.0	1.0	0.3
Impedance of whole body	0.5	2.7	4.0	1.2	-2.0
Schizophrenia vs Biploar Disorder	0.4	0.5	0.9	1.0	-0.1
Blood Red Count	0.4	4.1	4.9	-2.2	-1.8
BMI	0.4	2.2	3.3	-1.8	1.0
Trunk fat percentage	0.4	1.4	2.1	-1.5	-0.8
Multivitamins +/- minerals	0.4	0.5	1.0	0.1	-1.0
Supplements: Glucosamine	0.4	0.5	0.9	0.2	1.0
Body mass index (BMI)	0.4	1.7	2.3	-1.5	1.0
Financial difficulties in last 2 years	0.4	0.5	0.9	1.0	0.2
Heart attack	0.4	0.6	0.8	-0.6	-0.9
Impedance of arm (right)	0.4	2.1	3.0	1.0	-1.7
Hip circumference	0.4	1.7	3.0	-1.7	-0.6
Medication: Lansoprazole	0.4	0.4	0.8	0.1	0.9
Lung cancer (father)	0.4	0.5	1.0	-0.2	-1.0
Arm fat mass (right)	0.4	1.7	3.2	-1.8	-0.3
Hair/balding pattern: Pattern 4	0.4	1.1	1.8	-1.4	0.5
Headache pain in last month	0.4	0.8	0.8	-0.9	-0.9
Wheeze or whistling in the chest in last year	0.4	0.8	1.5	-1.2	-0.2
Pulse wave peak to peak time	0.4	0.4	0.5	0.7	0.6
Medication: Omeprazole	0.4	0.5	0.8	-0.9	0.4
Whole body fat mass	0.4	1.7	3.2	-1.8	-0.4
Long-standing illness, disability or infirmity	0.4	0.6	1.0	0.6	1.0
Breast cancer (self-reported)	0.4	0.5	0.6	-0.7	-0.8
Arm fat mass (left)	0.4	1.5	3.0	-1.7	-0.2
Commuting to job workplace: Public transport	0.4	0.5	0.7	-0.9	0.5
Bipolar Disorder (2018)	0.3	0.5	0.9	0.2	0.9
Mean Putamen Volume	0.3	0.3	0.6	-0.8	-0.3
Neuroticism (2016)	0.3	0.5	0.6	-0.6	-0.8
Primary Biliary Cirrhosis	0.3	0.4	0.7	0.3	0.9
Waist Hip Ratio (WHR)	0.3	1.5	2.9	0.2	-1.7
Leg fat-free mass (left)	0.3	1.6	3.1	-1.8	-0.4
Average weekly fortified wine intake	0.3	0.3	0.6	-0.8	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.4	0.5	0.7
Taking other prescription medications	0.3	0.5	1.0	-1.0	-0.1
Age when periods started (menarche)	0.3	0.8	1.5	-0.3	1.2
Stomach or abdominal pain in last month	0.3	0.4	0.4	-0.6	0.6
Leg predicted mass (left)	0.3	1.6	3.0	-1.7	-0.3
Waist circumference	0.3	1.1	1.6	-1.3	-0.7
Time employed in main current job	0.3	0.3	0.4	-0.5	-0.6
Hair/balding pattern: Pattern 3	0.3	0.4	0.6	-0.8	-0.5
Number of live births	0.3	0.4	0.4	-0.7	0.6
Pulse rate	0.3	0.5	0.6	-0.8	0.6
Depression (self-reported)	0.3	0.4	0.4	-0.7	-0.5
Birth weight	0.3	0.8	1.1	-1.1	-0.6
Exposure to tobacco smoke outside home	0.3	0.4	0.8	0.9	-0.2
Heart disease (mother)	0.3	0.4	0.7	0.1	-0.8
Leg fat mass (right)	0.3	1.0	2.0	-1.4	0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.6	-0.8	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.8	0.0	0.9
Leg fat-free mass (right)	0.3	1.7	3.0	-1.7	-0.6
Average weekly red wine intake	0.3	0.4	0.8	-0.2	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.4	0.5	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.5	-0.7	-0.4
Mineral and other dietary supplements	0.3	0.4	0.7	-0.9	0.1
Leg predicted mass (right)	0.3	1.8	3.2	-1.8	-0.6
Supplements: Fish oil (including cod liver oil)	0.3	0.3	0.5	-0.4	-0.7
Age started oral contraceptive pill	0.3	0.4	0.7	0.2	-0.9
Myopia	0.3	0.4	0.8	0.4	0.9
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.5	-0.7	0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.3	0.4	-0.5	-0.6
Neuroticism (Nagel 2018)	0.2	0.4	0.6	-0.7	-0.4
Rheumatoid Arthritis	0.2	0.3	0.5	-0.4	0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	-0.6	0.1
Fed-up feelings	0.2	0.3	0.6	0.2	-0.8
Arm fat percentage (right)	0.2	0.7	1.3	-1.1	0.1
Prospective memory result	0.2	0.2	0.4	0.6	-0.1
Body fat percentage	0.2	0.8	1.5	-1.2	-0.3
Qualifications: College or University degree	0.2	0.5	0.7	0.6	-0.9
Alcohol intake frequency.	0.2	0.5	0.9	-1.0	-0.1
Family relationship satisfaction	0.2	0.2	0.3	-0.6	0.2
Arm fat percentage (left)	0.2	0.7	1.2	-1.1	0.3
Medication: Gliclazide	0.2	0.2	0.2	0.4	-0.4
Miserableness	0.2	0.4	0.4	-0.6	0.6
Medication: Paracetamol	0.2	0.4	0.4	-0.7	-0.5
Illnesses of father: High blood pressure	0.2	0.2	0.3	0.6	-0.3
Alcohol drinker status: Never	0.2	0.2	0.3	0.4	0.5
Average weekly beer plus cider intake	0.2	0.3	0.4	0.4	0.7
Leg fat mass (left)	0.2	0.9	1.9	-1.4	0.1
Depressed Affect (Nagel 2018)	0.1	0.3	0.4	-0.4	0.6
Depression (Nagel 2018)	0.1	0.1	0.1	-0.2	0.3
Ulcerative Colitis (UC)	0.1	0.2	0.4	-0.1	-0.6
Fasting Glucose	0.1	0.1	0.1	-0.3	-0.4
Respiratory disease	0.1	0.3	0.6	-0.1	-0.8
Neuroticism	0.1	0.3	0.4	-0.6	-0.4
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	0.3	-0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.1	0.4	0.3
Qualifications: CSEs or equivalent	0.1	0.1	0.2	-0.0	0.5
Had other major operations	0.1	0.1	0.2	0.1	0.4
Forced vital capacity (FVC)	0.1	0.4	0.4	-0.7	-0.6
Allergy	0.1	0.3	0.4	-0.6	-0.3
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	0.4	-0.7	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.3	0.1	-0.5
Mouth/teeth dental problems: Dentures	0.1	0.2	0.3	-0.6	-0.2
Asthma	0.1	0.1	0.2	-0.3	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.7	-0.3	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.2	-0.4	0.4
Birth weight of first child	0.1	0.3	0.3	0.5	-0.6
Medication: Paracetamol	0.1	0.1	0.2	-0.4	-0.1
Leg fat percentage (right)	0.1	0.4	0.4	-0.6	0.6
Age at first live birth	0.1	0.2	0.3	0.5	0.4
Medication: Seretide 50 evohaler	0.1	0.1	0.2	0.2	0.4
Illnesses of father: Heart disease	0.1	0.1	0.1	0.3	-0.3
Ever had bowel cancer screening	0.1	0.1	0.2	-0.3	0.4
Mother’s age at death	0.1	0.2	0.3	0.6	0.2
Financial situation satisfaction	0.1	0.1	0.2	-0.5	-0.2
Leg fat percentage (left)	0.1	0.4	0.7	-0.8	0.4
Lung FEV1/FVC ratio	0.0	0.2	0.3	-0.2	0.5
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.0	0.0	0.1
Vitamin and mineral supplements	0.0	0.0	0.0	-0.1	-0.0
Happiness	0.0	0.0	0.0	-0.2	0.1
Forced vital capacity (FVC), Best measure	0.0	0.0	0.0	-0.1	-0.2
Emphysema/chronic bronchitis	0.0	0.0	0.1	0.2	0.2
Pulse rate, automated reading	0.0	0.0	0.0	-0.0	-0.1
Asthma (self-reported)	0.0	0.0	0.1	-0.0	-0.3
Illnesses of father: None of the above (group 1)	0.0	0.0	0.1	-0.3	0.1
Basal cell carcinoma (self-reported)	0.0	0.1	0.1	0.1	-0.3

Hub : Genes

ARID1A

Models

Trait associations