[Hub]/) : Traits : HDL Cholesterol : ← →

chr15:62,636,766-64,056,437

Best TWAS P=1.79e-08 · Best GWAS P=1.95e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-244F12.3 0.16 0.12 lasso 5 0.10 6.5e-09 -5.4 -5.6 2.0e-08 0.87 0.02 0.98 FALSE
2 GTEx Adipose Visceral Omentum RP11-244F12.3 0.15 0.00 lasso 5 0.00 2.2e-01 -5.4 -5.4 8.1e-08 0.87 0.02 0.89 FALSE
3 GTEx Artery Coronary TPM1 0.32 0.09 lasso 6 0.03 2.6e-02 -5.3 -5.1 2.9e-07 0.80 0.03 0.93 FALSE
4 GTEx Artery Tibial TPM1 0.22 0.18 lasso 4 0.21 2.3e-16 -5.4 -5.3 9.1e-08 0.81 0.02 0.98 FALSE
5 GTEx Brain Caudate basal ganglia RP11-244F12.2 0.47 0.27 lasso 8 0.30 2.5e-09 -5.3 -5.4 5.3e-08 0.88 0.02 0.98 FALSE
6 GTEx Brain Frontal Cortex BA9 RP11-244F12.2 0.22 0.11 lasso 6 0.11 8.8e-04 -5.6 -5.6 1.8e-08 0.96 0.01 0.97 TRUE
7 GTEx Brain Hippocampus TPM1 0.34 0.10 lasso 5 0.17 1.0e-04 -5.3 -5.1 2.9e-07 0.87 0.02 0.88 FALSE
8 GTEx Brain Hippocampus RP11-244F12.2 0.36 0.39 lasso 6 0.36 2.4e-09 -5.3 -5.3 1.3e-07 0.88 0.01 0.98 FALSE
9 GTEx Brain Nucleus accumbens basal ganglia RP11-244F12.2 0.33 0.24 enet 22 0.15 7.2e-05 -4.1 -5.2 1.8e-07 0.77 0.07 0.82 FALSE
10 GTEx Nerve Tibial TPM1 0.14 0.04 lasso 9 0.04 9.8e-04 -5.4 -5.3 1.3e-07 0.88 0.02 0.98 FALSE
11 GTEx Nerve Tibial RP11-244F12.2 0.16 0.00 lasso 8 0.02 9.9e-03 -5.4 -5.4 5.9e-08 0.89 0.02 0.97 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LACTB 0.04 0.01 blup 52 0.02 2.5e-03 -4.4 5.2 2.0e-07 -0.76 0.13 0.67 FALSE