Best TWAS P=6.09e-42 · Best GWAS P=2.92e-96 conditioned to 1.93e-45
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADAM10 | 0.06 | 0.01 | blup | 583 | 0.03 | 3.8e-04 | -1.8 | 5.2 | 2.0e-07 | 0.29 | 0.15 | 0.57 | TRUE |
| 2 | GTEx | Thyroid | ADAM10 | 0.13 | 0.00 | lasso | 3 | 0.00 | 1.6e-01 | -2.4 | -5.2 | 2.4e-07 | -0.18 | 0.18 | 0.24 | FALSE |
| 3 | NTR | Blood | LIPC | 0.08 | 0.02 | bslmm | 587 | 0.04 | 8.7e-13 | 4.7 | 7.4 | 1.6e-13 | 0.03 | 1.00 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | LIPC | 0.11 | 0.03 | blup | 186 | 0.00 | 1.0e-01 | 1.2 | -13.6 | 6.1e-42 | -0.39 | 0.04 | 0.11 | TRUE |