Best TWAS P=2.34e-10 · Best GWAS P=4.4e-21 conditioned to 1.89e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Lung Adenocarcinoma | APOC1 | 0.06 | 0.05 | enet | 8 | 0.06 | 4.6e-07 | 4.8 | 6.3 | 2.3e-10 | -0.11 | 0.76 | 0.01 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | APOC4 | 0.07 | 0.08 | lasso | 2 | 0.08 | 5.2e-09 | 4.8 | 6.0 | 2.1e-09 | -0.03 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | APOC1 | 0.11 | 0.08 | lasso | 4 | 0.08 | 2.7e-08 | 4.8 | 5.1 | 2.9e-07 | 0.01 | 0.99 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | APOE | 0.13 | 0.09 | lasso | 3 | 0.11 | 3.9e-08 | 4.8 | 6.2 | 4.8e-10 | -0.03 | 0.75 | 0.01 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | APOC4 | 0.09 | 0.08 | enet | 9 | 0.12 | 1.9e-11 | 3.7 | 5.4 | 7.2e-08 | -0.05 | 1.00 | 0.00 | FALSE |