Best TWAS P=4.04e-08 · Best GWAS P=4.04e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ANGPTL4 | 0.04 | 0.04 | lasso | 1 | 0.04 | 4.3e-04 | -5.5 | 5.5 | 4.0e-08 | -1.00 | 0.00 | 0.92 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ANGPTL4 | 0.01 | 0.01 | lasso | 1 | 0.00 | 4.4e-02 | -5.4 | 5.4 | 8.5e-08 | -1.00 | 0.00 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | ANGPTL4 | 0.11 | 0.07 | lasso | 3 | 0.06 | 4.9e-04 | -5.2 | 5.2 | 1.6e-07 | -1.00 | 0.01 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MYO1F | 0.05 | 0.01 | blup | 42 | 0.03 | 2.2e-04 | 4.2 | 5.4 | 6.5e-08 | -0.16 | 0.00 | 0.23 | TRUE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | MARCH2 | 0.08 | 0.01 | enet | 8 | 0.04 | 1.3e-03 | -2.9 | -5.1 | 2.7e-07 | 0.45 | 0.04 | 0.36 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ANGPTL4 | 0.16 | 0.16 | enet | 10 | 0.18 | 2.4e-18 | -5.2 | 5.4 | 7.9e-08 | -0.93 | 0.01 | 0.99 | FALSE |