Best TWAS P=4.95e-08 · Best GWAS P=6.19e-08 conditioned to 0.414
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Liver | CELSR2 | 0.39 | 0.36 | lasso | 1 | 0.35 | 1.0e-10 | 5.3 | 5.3 | 1.4e-07 | 1.00 | 0 | 0.99 | FALSE |
| 2 | GTEx | Muscle Skeletal | CELSR2 | 0.41 | 0.31 | lasso | 4 | 0.30 | 2.4e-30 | 5.3 | 5.1 | 3.0e-07 | 0.99 | 0 | 0.99 | FALSE |
| 3 | GTEx | Whole Blood | PSRC1 | 0.14 | 0.04 | lasso | 3 | 0.03 | 6.9e-04 | 5.4 | 5.4 | 7.8e-08 | 1.00 | 0 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | SORT1 | 0.23 | 0.16 | lasso | 4 | 0.16 | 4.6e-08 | 5.4 | 5.5 | 4.9e-08 | 0.94 | 0 | 1.00 | TRUE |