Hub : Genes

CELSR2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.035	0.0170	1.0e-02	0.002	0.003	0.003	0.003	0.011	1.6e-01	1.2e-01	1.2e-01	1.4e-01	1.5e-02
2	GTEx	Liver	0.394	0.0950	7.8e-04	0.358	NA	0.305	NA	0.353	7.3e-11	NA	3.3e-09	NA	1.1e-10
3	GTEx	Muscle Skeletal	0.410	0.0535	5.0e-16	0.310	NA	0.283	NA	0.305	6.2e-31	NA	7.3e-28	NA	2.4e-30
4	GTEx	Skin Sun Exposed Lower leg	0.185	0.0710	2.1e-03	0.047	NA	0.055	NA	0.061	8.7e-05	NA	2.3e-05	NA	8.1e-06
5	METSIM	Adipose	0.128	0.0351	1.1e-07	0.037	0.048	0.058	0.050	0.056	3.0e-06	1.1e-07	5.0e-09	5.8e-08	8.3e-09
6	ROSMAP	Brain Pre-frontal Cortex	0.253	0.0396	5.6e-17	0.214	0.167	0.221	0.209	0.229	5.4e-27	7.1e-21	6.5e-28	2.7e-26	4.9e-29
7	TCGA	Colon Adenocarcinoma	0.120	0.0570	2.7e-03	0.005	0.036	0.038	NA	0.010	1.6e-01	3.6e-03	3.0e-03	NA	8.6e-02
8	TCGA	Stomach Adenocarcinoma	0.082	0.0420	8.6e-03	0.003	0.023	0.006	NA	-0.002	1.9e-01	8.1e-03	1.1e-01	NA	4.9e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.0	1.5	3.7	-1.8	1.0	1.0	1.5	0.6	0.7	0.2	1.9
Bipolar Disorder or Schizophrenia	0.7	1.7	3.1	-0.4	1.4	1.6	1.6	1.7	1.5	-0.0	1.2
Depressed Affect (Nagel 2018)	0.8	1.7	3.0	-1.1	1.4	1.4	1.7	-0.9	1.2	1.6	0.5
Depression (Nagel 2018)	0.2	0.3	0.8	-0.9	0.4	0.3	0.4	-0.2	0.2	0.7	0.9
Intelligence (Savage-Jansen 2018)	1.0	3.0	10.8	-1.4	-0.2	-0.2	-0.4	-1.8	-0.3	-2.8	3.3
Neuroticism (Nagel 2018)	0.4	0.8	1.7	-1.1	0.8	0.7	1.3	-1.0	0.6	0.3	1.1
Schizophrenia (2018)	0.6	1.1	3.1	0.9	1.1	1.2	0.8	1.8	1.4	-0.2	-0.1
Schizophrenia vs Biploar Disorder	1.0	1.3	3.7	1.5	0.1	0.2	-0.8	1.4	0.5	-1.3	-1.9
Worry (Nagel 2018)	0.1	0.2	0.6	-0.4	0.0	0.0	0.2	-0.2	0.3	-0.8	0.5
Alzheimer’s Disease (in mother)	0.8	0.9	2.0	0.4	-1.1	-1.1	-1.3	0.5	-1.0	-1.4	-0.4
Alzheimer’s Disease (in father)	0.9	0.9	3.0	0.9	0.6	0.5	0.5	-1.7	0.5	1.5	-0.6
Alzheimer’s Disease (including proxy)	0.5	0.7	3.1	-0.1	-0.5	-0.6	-0.9	-1.8	-0.6	-0.1	-0.8
Crohns Disease (2017)	0.4	1.0	2.0	0.8	-0.9	-0.9	-1.4	1.1	-1.4	0.3	-0.5
Irritable Bowel Disease (IBD)	0.2	0.6	1.2	0.3	-0.7	-0.7	-0.7	1.1	-1.1	0.4	-0.4
Ulcerative Colitis (UC)	0.2	0.3	0.7	-0.3	-0.6	-0.6	-0.4	0.8	-0.8	-0.1	-0.1
Major Depression (MDD)	1.3	1.5	4.7	0.3	1.2	1.3	2.2	0.2	1.3	-0.2	1.6
Reaction Time	0.8	1.5	4.5	-1.2	0.8	0.7	0.9	-2.0	0.8	2.1	-0.2
Verbal and Numeric Reasoning (VNR)	0.4	1.1	4.5	-0.8	-0.2	-0.3	-0.9	-0.8	-0.3	-1.4	2.1
Breast Cancer	0.6	1.4	6.1	0.4	1.0	1.1	2.5	0.5	1.3	0.8	-0.2
Ovarian Cancer	0.1	0.2	0.5	-0.3	0.3	0.3	0.5	-0.3	0.3	0.7	-0.2
Prostate Cancer	0.2	0.2	1.1	1.1	-0.2	-0.2	-0.2	0.7	0.3	-0.4	-0.1
Age at First Birth	0.4	0.5	1.6	-0.8	0.5	0.5	1.3	-0.9	0.3	0.3	-0.5
Bipolar Disorder (2011)	0.3	0.3	1.2	-0.3	-0.5	-0.4	-0.5	1.1	-0.8	0.0	0.0
Body Mass Index (BMI) (2010)	1.8	2.4	3.7	-1.2	1.9	1.8	1.4	-1.3	1.8	1.9	0.4
Coronary Artery Disease (CAD)	18.3	21.9	31.1	4.4	-5.4	-5.3	-5.5	3.6	-5.6	-3.2	-3.8
Crohns Disease (2012)	1.3	2.0	3.6	1.1	-1.6	-1.6	-1.9	1.6	-1.6	-0.9	-0.9
Mean Putamen Volume	1.1	1.3	3.8	0.7	-0.8	-0.8	-1.9	-1.0	-1.1	-0.9	-1.3
Fasting Glucose	1.8	2.2	5.3	-1.1	1.4	1.5	2.3	-1.1	2.0	0.3	1.3
HbA1C	0.3	0.3	1.1	-0.5	0.0	-0.0	0.3	-0.4	-0.3	0.9	1.0
HDL Cholesterol	9.6	16.0	27.7	-4.6	5.3	5.1	3.4	-2.2	4.7	3.1	2.1
LDL Cholesterol	296.3	468.9	767.3	17.1	-27.7	-27.5	-23.4	9.3	-27.3	-17.2	-16.1
Lupus	0.5	0.8	3.5	1.1	-0.3	-0.4	-0.3	-1.9	-0.3	-1.0	0.2
Neuroticism (2016)	0.6	0.9	1.9	-0.2	-1.2	-1.3	-0.4	-0.7	-1.3	-1.4	0.0
Primary Biliary Cirrhosis	0.7	1.0	4.1	-0.5	0.6	0.6	0.9	1.4	0.3	2.0	0.2
Rheumatoid Arthritis	0.8	1.1	4.6	1.3	-0.9	-0.8	-0.2	0.4	-0.7	-2.1	0.4
Schizophrenia (2014)	0.3	0.6	1.3	0.3	0.6	0.7	0.1	1.1	0.9	-0.8	-0.8
Triglycerides	1.6	2.7	4.2	1.7	-1.8	-1.7	-2.1	0.5	-1.6	-1.8	-1.4
Type 2 Diabetes (T2D) (2012)	4.0	4.6	10.3	-3.2	2.1	2.0	1.1	-3.1	1.5	2.1	0.0
Ulcerative Colitis	0.2	0.3	0.9	-0.1	-0.6	-0.6	0.1	0.9	-0.5	0.3	-0.7
Blood Eosinophil Count	0.5	4.0	8.0	2.8	-1.8	-1.8	-2.8	-0.5	-2.2	-2.3	0.0
Blood Platelet Count	0.0	0.5	1.4	0.5	0.7	0.7	0.2	-0.5	0.5	1.2	-0.9
Blood Red Count	0.2	1.8	8.4	0.9	-0.0	-0.1	0.3	-2.3	0.1	-0.3	2.9
Blood White Count	0.6	4.2	8.3	0.6	2.9	2.8	1.7	-0.7	2.9	2.2	0.3
Heel T-Score	2.1	16.9	27.2	-3.5	5.0	4.9	3.1	-2.9	4.6	2.7	5.2
BMI	0.2	1.4	8.4	-0.5	0.5	0.5	-1.3	-0.1	0.4	-0.2	2.9
Height	1.6	29.9	55.2	-4.0	7.3	7.3	6.5	-1.8	7.4	3.9	1.1
Waist Hip Ratio (WHR)	0.9	4.0	10.1	-2.4	1.8	1.6	1.8	-3.2	1.4	1.4	1.9
Systolic Blood Pressure	0.2	1.2	3.0	-0.4	-1.3	-1.4	-0.9	0.2	-1.7	-0.6	1.3
Smoking Status	2.5	5.9	11.1	-2.5	3.3	3.3	1.5	-1.7	3.2	1.4	1.5
Allergy or Eczema	0.4	1.0	3.2	-1.1	0.6	0.5	-0.1	-1.8	0.3	1.4	0.9
Cardiovascular Disease	17.4	57.6	99.2	7.1	-10.0	-9.8	-7.1	3.4	-9.6	-7.4	-2.4
Hypothyroidism (self reported)	0.4	0.8	2.9	-0.2	-0.5	-0.5	-1.7	-0.5	-0.8	-0.8	-1.4
Respiratory disease	1.6	3.6	10.0	-1.0	2.0	2.1	1.7	-1.0	2.3	-0.7	3.2
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.0	0.4	0.8	0.8	-1.4	-0.5	0.8	0.6	-0.1
Lung FEV1/FVC ratio	3.5	17.8	32.9	3.2	-5.3	-5.3	-5.7	1.8	-5.2	-2.2	-2.9
Lung FVC	0.8	4.0	10.6	-0.4	1.9	2.1	3.3	2.6	1.6	1.3	1.4
Neuroticism	0.5	1.2	2.4	-1.3	0.7	0.7	1.2	-1.6	0.8	0.1	1.4
Chronotype (morning person)	1.0	2.3	8.4	0.4	-0.5	-0.3	-0.2	2.9	-0.1	-1.7	2.5
Hair Pigment	0.0	0.6	2.9	-0.5	-0.3	-0.3	-0.6	-0.2	-0.5	0.8	-1.7
Tanning	0.3	3.4	6.1	-1.9	2.3	2.2	1.2	-1.1	1.9	1.0	2.5
Hand grip strength (left)	1.3	3.4	7.9	-0.6	2.6	2.7	1.6	1.1	2.8	-0.3	0.8
Number of treatments/medications taken	8.4	15.2	23.2	3.1	-4.8	-4.7	-4.3	1.6	-4.8	-4.6	-1.4
Average weekly spirits intake	0.5	0.6	2.9	1.2	-0.0	-0.1	-0.2	-1.7	-0.1	0.4	-0.6
Sensitivity / hurt feelings	0.9	1.6	3.6	-1.0	1.2	1.3	1.5	-0.6	1.3	-0.7	1.9
Frequency of depressed mood in last 2 weeks	0.7	1.0	4.2	-2.0	0.6	0.5	0.2	0.0	0.3	1.7	0.4
Hearing difficulty/problems: Yes	4.1	6.2	11.5	-1.3	3.4	3.4	2.6	-1.2	3.4	2.1	1.1
Relative age of first facial hair	0.3	0.6	2.4	0.5	-0.1	-0.2	0.4	-1.0	0.2	0.8	-1.5
Other serious medical condition/disability diagnosed by doctor	4.5	5.8	8.8	2.5	-3.0	-3.0	-2.8	0.5	-2.9	-1.9	-1.7
Ever used hormone-replacement therapy (HRT)	1.7	2.2	5.3	-0.6	1.7	1.6	1.2	-1.4	1.4	2.3	-1.0
Ever had hysterectomy (womb removed)	0.4	0.5	2.0	-0.2	0.4	0.4	1.4	0.4	0.7	-0.2	-1.0
Systolic blood pressure, automated reading	0.3	0.9	2.6	-1.6	0.2	0.1	0.5	-1.6	-0.1	-0.1	1.3
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.8	0.7	-0.2	-0.3	-0.9	-0.8	-0.4	0.1	0.7
Angina	23.8	31.2	47.1	5.7	-6.9	-6.7	-5.7	3.2	-6.7	-4.7	-3.9
Medication for hormone replacement therapy	0.5	0.5	2.0	1.0	0.5	0.6	0.3	-0.2	0.6	1.4	0.4
Vitamin and mineral supplements	0.3	0.4	1.0	0.7	-0.6	-0.6	-0.9	0.3	-0.6	0.0	-1.0
Supplements: Zinc	0.6	0.7	1.3	-0.6	1.0	1.1	0.6	-0.1	1.2	-0.0	0.9
Medication: Co-codamol	1.0	1.1	1.7	1.3	-1.1	-1.1	-1.1	0.5	-0.9	-1.0	-1.2
Medication: Metformin	0.5	0.7	1.6	0.3	1.2	1.3	-1.1	0.2	0.8	1.1	0.1
Diabetes (father)	3.5	4.3	7.3	-1.2	2.3	2.2	1.7	-2.1	2.7	2.7	-0.8
Diabetes (mother)	2.1	2.7	6.1	-1.1	2.3	2.3	1.4	-1.1	2.5	0.5	0.4
Severe depression (siblings)	0.5	0.5	1.5	0.5	-0.2	-0.2	-1.2	1.1	-0.1	-0.8	-0.8
Pack years adult smoking proportion	0.6	0.9	2.6	1.4	0.3	0.3	-0.1	-0.7	0.3	1.3	-1.6
Impedance of leg (right)	1.6	7.7	30.5	1.8	-2.9	-3.0	-1.1	0.8	-2.8	0.6	-5.5
Leg fat-free mass (left)	1.2	6.3	12.2	-1.4	3.4	3.5	1.9	0.0	3.4	0.4	3.1
Trunk fat percentage	0.5	1.9	5.1	1.0	-1.2	-1.3	-2.0	-0.4	-1.3	0.6	-2.3
Hand grip strength (right)	1.7	4.6	9.3	-0.7	3.0	3.0	1.9	1.7	3.0	1.2	1.3
Townsend deprivation index at recruitment	0.7	0.9	2.7	0.9	-0.4	-0.3	1.2	1.6	0.1	-0.4	1.5
Current tobacco smoking	2.2	3.7	5.6	-2.2	2.4	2.3	0.8	-2.2	2.4	1.6	-0.4
Average weekly fortified wine intake	0.9	1.1	4.8	-0.8	0.7	0.6	0.9	-2.2	0.6	-0.4	1.1
Maternal smoking around birth	0.8	1.2	2.7	-0.1	-1.2	-1.2	-0.9	1.6	-1.5	0.2	-0.8
Fed-up feelings	2.8	5.0	7.8	-2.1	2.4	2.3	2.7	-0.9	2.2	2.8	2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.3	-0.6	-0.8	-0.9	-1.0	0.3	-1.1	-0.3	0.6
Relative age voice broke	0.2	0.3	0.9	-0.8	-0.1	-0.2	-0.1	-0.9	-0.3	0.9	0.3
Taking other prescription medications	1.0	1.5	4.6	0.5	-1.1	-1.0	-1.9	0.4	-1.0	-2.1	-0.3
Age when periods started (menarche)	0.5	1.1	2.8	0.3	-0.9	-1.0	0.6	-1.4	-0.2	-1.3	-1.7
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.1	0.2	-0.1	-0.1	0.8	-0.6	0.0	0.9	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	5.7	-0.9	1.8	1.7	0.5	-0.4	1.2	0.7	2.4
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	4.1	-1.2	0.5	0.4	0.7	0.8	0.3	2.0	0.3
Qualifications: CSEs or equivalent	2.1	2.7	4.5	1.9	-1.9	-1.9	-0.5	2.1	-2.0	-1.5	0.3
Serious illness, injury or assault to yourself	2.4	2.9	5.3	1.4	-2.2	-2.1	-1.0	1.2	-2.3	-1.7	-1.2
High blood pressure	0.7	1.9	8.5	-0.9	0.4	0.2	1.3	-2.9	-0.0	0.9	1.6
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.8	0.1	0.1	0.1	-0.5	-0.9	-0.0	0.6	-0.2
Multivitamins +/- minerals	0.3	0.4	1.5	-0.7	0.5	0.5	0.4	0.5	0.6	-0.3	1.2
Stomach or abdominal pain in last month	0.6	0.7	2.6	0.8	-0.0	0.1	-0.2	1.5	0.6	0.4	-1.6
Supplements: Glucosamine	2.8	3.6	7.9	-1.4	2.4	2.4	1.1	-1.9	2.8	0.0	1.7
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	3.0	0.0	0.5	0.7	-0.4	0.8	0.8	-1.7	0.8
Medication: Atenolol	5.8	7.2	12.7	1.8	-3.2	-3.2	-3.6	0.4	-3.6	-2.2	-1.8
Medication: Levothyroxine sodium	0.3	0.6	1.5	-0.5	-0.6	-0.7	-0.5	-1.1	-0.7	0.3	-1.2
Sitting height	0.1	1.0	2.0	0.1	1.3	1.3	0.8	-0.3	1.4	0.9	-0.9
Chronic bronchitis/emphysema (father)	0.4	0.4	1.6	-0.3	-0.2	-0.2	-0.7	0.8	-0.1	-1.3	0.8
High blood pressure (mother)	1.3	1.8	3.7	1.6	-1.5	-1.4	-1.2	1.9	-1.3	-0.8	0.6
Body mass index (BMI)	0.1	0.6	3.1	-0.4	0.2	0.2	-0.9	-0.5	-0.1	-0.2	1.8
Impedance of leg (left)	1.6	7.8	32.5	1.3	-2.9	-3.0	-1.2	0.2	-2.8	1.2	-5.7
Leg predicted mass (left)	1.3	6.6	12.9	-1.5	3.5	3.6	2.0	0.0	3.5	0.4	3.1
Trunk fat mass	0.1	0.3	0.8	0.2	0.1	0.1	-0.8	-0.7	0.1	0.7	-0.9
Waist circumference	0.4	1.4	3.8	-0.8	1.2	1.1	0.3	-1.9	1.1	0.7	1.5
Number of incorrect matches in round	0.4	0.7	4.7	-0.5	0.3	0.3	2.2	0.2	0.1	0.7	-0.0
Past tobacco smoking	0.4	0.7	3.6	1.1	-0.2	-0.2	-0.6	-0.3	-0.1	0.1	-1.9
Alcohol usually taken with meals	0.2	0.3	0.7	-0.2	-0.8	-0.8	-0.1	-0.1	-0.7	-0.5	0.4
Nervous feelings	0.2	0.3	1.3	-0.8	0.1	0.0	0.1	-0.2	0.1	-1.2	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	3.1	-0.9	-1.4	-1.5	-1.1	0.3	-1.8	0.6	-1.1
Hearing difficulty/problems with background noise	1.1	1.8	3.8	-0.9	1.7	1.7	1.7	-1.0	1.9	0.2	0.7
Hair/balding pattern: Pattern 2	0.3	0.4	1.1	0.9	0.2	0.2	1.1	0.3	0.5	-0.8	0.4
Had menopause	2.6	3.2	6.2	-0.5	2.0	1.9	2.5	-2.0	2.2	1.3	-0.8
Had other major operations	0.1	0.1	0.5	0.7	-0.1	-0.2	-0.1	0.4	0.2	-0.1	-0.5
Forced vital capacity (FVC)	0.5	1.8	10.8	0.1	0.8	1.0	0.5	3.3	0.5	0.6	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.1	6.9	-1.7	2.1	2.0	0.9	-0.5	1.6	1.7	2.6
Ever unenthusiastic/disinterested for a whole week	2.0	2.5	6.8	0.9	-1.6	-1.5	-1.8	2.6	-1.4	-1.1	-1.1
Qualifications: None of the above	0.9	1.9	9.6	-0.1	0.5	0.4	0.9	-0.5	0.2	3.1	-2.1
Financial difficulties in last 2 years	0.8	1.1	2.0	1.0	-1.4	-1.4	-0.2	0.6	-1.2	-1.3	0.3
Mouth/teeth dental problems	0.5	0.7	1.1	-0.9	1.0	1.0	0.7	1.0	1.1	0.4	0.5
Heart attack	18.1	23.2	31.3	5.1	-5.6	-5.5	-5.1	1.5	-5.5	-4.9	-4.0
Allergy	0.1	0.3	0.5	0.7	-0.6	-0.7	0.2	-0.5	-0.4	-0.5	-0.6
Pain all over the body in last month	0.5	0.6	1.2	-0.2	-1.1	-1.1	-0.6	0.9	-0.9	-0.0	0.6
Diabetes (self-reported)	0.3	0.4	1.9	0.4	0.2	0.2	-1.4	-0.9	-0.0	-0.4	-0.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.5	-0.5	0.8	0.9	0.4	-0.5	1.2	0.0	0.4
Medication: Ramipril	3.5	4.5	6.8	2.2	-2.4	-2.4	-2.5	0.2	-2.5	-2.6	-0.9
Medication: Simvastatin	60.7	89.1	153.8	7.4	-12.4	-12.3	-9.6	2.3	-12.2	-8.5	-5.9
Fluid intelligence score	0.3	0.7	3.4	-0.6	-0.2	-0.2	-0.5	-0.4	-0.1	-1.8	1.2
Illnesses of siblings	1.8	2.6	3.9	-1.0	2.0	2.0	1.8	-0.2	1.9	1.2	1.9
Neuroticism score	0.9	1.8	5.3	-2.3	1.2	1.2	1.2	-1.1	1.1	0.9	1.4
Weight	0.5	2.4	4.6	-1.1	2.1	2.2	0.9	-1.0	2.1	1.0	1.3
Impedance of arm (right)	2.4	11.3	49.3	2.3	-3.1	-3.2	-2.6	0.6	-2.9	0.2	-7.0
Arm fat percentage (right)	0.4	1.6	5.2	0.7	-1.3	-1.3	-2.3	-0.4	-1.4	0.0	-1.4
Trunk fat-free mass	2.7	15.4	26.2	-3.0	5.1	5.1	4.1	-1.2	5.1	1.5	4.0
Hip circumference	0.0	0.2	0.7	0.8	0.1	0.2	-0.5	-0.1	0.3	0.3	-0.4
Time employed in main current job	0.7	0.9	3.6	-1.0	-0.7	-0.7	-0.4	1.9	-0.9	0.5	-0.1
Alcohol intake versus 10 years previously	2.2	3.2	5.4	-0.4	2.1	2.2	2.2	-0.3	2.0	1.3	2.3
Father’s age at death	9.3	12.5	20.7	-3.1	4.5	4.5	2.8	-2.1	4.3	1.6	3.9
Worrier / anxious feelings	1.1	2.0	4.0	-1.3	1.9	2.0	1.4	-0.8	2.0	0.6	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	2.7	-0.5	-1.1	-1.2	-1.0	-0.2	-1.6	-0.4	0.8
Falls in the last year	0.2	0.2	0.7	0.9	0.6	0.6	0.4	0.1	0.4	0.3	0.3
Hair/balding pattern: Pattern 3	0.5	0.7	0.9	0.9	0.9	0.9	0.5	-0.7	0.8	-0.9	0.9
Number of live births	0.8	1.2	5.4	0.2	0.2	0.1	-1.1	-1.3	0.0	1.1	-2.3
Forced expiratory volume in 1-second (FEV1)	0.7	2.2	13.8	0.8	-0.5	-0.4	-0.7	3.7	-0.8	0.3	-1.3
Pulse rate	1.3	2.2	6.0	0.9	-1.6	-1.5	-1.7	2.4	-1.5	-0.2	-0.8
Happiness	0.7	0.9	3.8	-1.9	0.3	0.2	0.5	0.9	0.1	0.9	1.1
Noisy workplace	2.4	2.9	11.3	-1.4	1.6	1.5	1.1	-1.3	1.3	3.4	-0.9
Qualifications: A levels/AS levels or equivalent	0.8	1.8	9.1	0.2	-0.4	-0.4	-1.4	0.6	-0.3	-3.0	1.6
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	2.7	1.6	-0.9	-0.9	-0.4	0.8	-0.9	-0.9	1.2
Mouth/teeth dental problems: Dentures	0.3	0.6	2.3	-0.1	0.3	0.2	-0.1	-1.5	-0.1	-1.0	1.1
Asthma	0.7	1.4	5.6	0.1	0.6	0.7	0.8	1.5	0.8	-1.0	2.4
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	2.7	0.6	0.8	0.9	1.5	1.7	1.1	0.5	1.0
Medication: Cholesterol lowering	92.0	143.0	243.4	9.9	-15.6	-15.5	-12.4	3.7	-15.3	-10.8	-6.7
Depression (self-reported)	0.8	1.0	5.8	-2.4	0.2	0.2	-0.3	0.5	0.1	0.7	-1.2
Medication: Lansoprazole	0.2	0.2	0.9	-0.6	0.4	0.4	0.4	-0.1	0.4	0.1	0.9
Prospective memory result	1.8	2.2	5.5	-1.0	2.0	2.0	1.6	-0.7	2.3	-0.1	0.5
Lung cancer (father)	2.3	2.7	5.6	-0.4	1.8	1.8	1.9	-0.5	2.0	2.4	-1.1
Illnesses of mother	1.3	1.6	4.0	-1.7	1.3	1.2	1.2	-0.1	1.0	2.0	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	12.1	0.1	0.6	0.7	-0.1	3.5	0.3	1.1	-0.2
Pulse wave Arterial Stiffness index	0.6	0.6	2.4	-0.8	-0.2	-0.4	-0.9	-1.5	-0.0	0.5	-0.9
Impedance of arm (left)	2.0	9.3	35.4	2.2	-3.1	-3.1	-2.4	0.5	-2.9	0.1	-6.0
Arm fat mass (right)	0.1	0.3	0.6	-0.4	0.5	0.5	-0.8	-0.6	0.3	0.7	0.3
Trunk predicted mass	2.7	15.4	26.2	-3.0	5.1	5.1	4.1	-1.2	5.1	1.5	4.0
Standing height	1.2	12.2	24.5	-2.0	4.7	4.7	4.0	-1.4	5.0	2.6	-0.7
Length of working week for main job	0.8	0.9	2.7	-0.4	-1.0	-1.0	-1.1	-0.0	-1.0	-0.4	1.6
Exposure to tobacco smoke at home	1.1	1.3	6.5	0.3	-1.0	-1.0	-1.0	-0.1	-0.6	0.6	-2.5
Breastfed as a baby	0.7	0.9	2.2	-0.4	1.3	1.3	0.0	-1.5	1.1	-0.1	0.3
Tense / ‘highly strung’	0.9	1.4	2.6	0.3	-1.5	-1.5	-1.4	0.9	-1.2	-1.6	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	6.5	-0.4	-0.3	-0.2	-0.8	2.5	0.2	-0.7	0.6
Hair/balding pattern: Pattern 4	0.3	0.7	2.9	-1.7	-0.3	-0.3	-0.2	0.5	-0.7	1.3	0.1
Birth weight of first child	1.0	1.8	7.1	-1.3	1.4	1.4	0.4	0.3	1.1	0.6	2.7
Peak expiratory flow (PEF)	1.1	2.6	9.5	2.6	-0.7	-0.5	-1.1	3.1	-0.5	-0.6	-1.4
Pulse wave reflection index	1.0	1.2	4.8	-1.8	0.5	0.3	0.0	-2.2	0.3	1.1	0.1
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.0	-1.0	0.2	0.2	0.9	-0.8	0.3	0.7	0.3
Loud music exposure frequency	0.9	1.0	4.6	0.9	0.4	0.4	2.1	0.2	0.6	-0.3	1.4
Qualifications: O levels/GCSEs or equivalent	1.6	2.5	12.6	2.1	-0.9	-0.8	-1.1	0.0	-0.3	-3.5	0.7
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.9	0.3	-1.4	-1.4	-0.5	-0.1	-1.2	0.2	-0.8
Blood clot in the leg (DVT)	0.6	0.8	2.4	-0.9	0.8	0.8	1.5	0.4	1.0	0.9	0.4
Medication: Paracetamol	0.2	0.4	1.2	1.1	-0.4	-0.3	-0.2	1.0	-0.1	-0.9	-0.0
Headache pain in last month	0.7	1.3	3.1	1.8	-1.1	-1.0	-1.2	1.0	-0.7	-0.9	-1.1
Medication for cholesterol, blood pressure or diabetes	30.0	49.6	81.7	-6.4	9.0	8.9	7.3	-1.6	8.9	6.9	3.3
Glaucoma (self-reported)	0.6	0.7	1.9	-0.7	1.4	1.4	0.1	0.4	1.1	0.6	-0.1
Gout (self-reported)	1.9	2.6	4.6	-1.4	2.1	2.1	1.1	-1.7	2.0	1.4	0.1
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	1.7	-0.5	0.3	0.3	-0.2	-0.7	0.1	0.4	-1.3
Medication: Amlodipine	0.9	1.3	4.8	2.2	-1.3	-1.1	-0.5	0.2	-1.2	-0.9	-0.0
Medication: Ventolin 100micrograms inhaler	3.2	4.2	7.6	-0.4	2.5	2.5	2.7	0.5	2.3	0.4	2.8
Birth weight	1.2	2.6	9.2	1.0	-1.5	-1.4	-2.2	0.5	-1.1	-3.0	0.3
Chronic bronchitis/emphysema (mother)	1.2	1.4	3.1	0.5	-1.3	-1.3	-1.8	-0.7	-1.4	-0.1	-1.4
High blood pressure (siblings)	2.4	3.5	6.3	1.2	-2.3	-2.3	-2.5	0.4	-2.3	-1.7	-1.1
Forced vital capacity (FVC), Best measure	0.7	2.6	8.8	-0.7	1.7	1.8	1.2	3.0	1.3	1.5	0.3
Body fat percentage	0.5	2.0	4.3	0.9	-1.4	-1.4	-2.1	-0.4	-1.5	0.4	-2.1
Leg fat percentage (right)	0.4	1.4	2.8	1.0	-1.3	-1.4	-1.2	-0.7	-1.4	0.3	-1.7
Arm fat-free mass (right)	2.6	13.3	21.3	-2.7	4.6	4.6	3.8	-0.8	4.6	1.8	4.3
Exposure to tobacco smoke outside home	1.6	2.1	12.0	-0.6	0.3	0.2	1.3	-1.6	-0.2	3.5	-0.2
Comparative body size at age 10	0.2	0.5	2.1	-0.3	0.0	0.1	-1.5	0.1	0.1	-0.8	1.1
Number of full brothers	0.4	0.5	1.3	0.2	0.6	0.6	0.0	1.1	1.2	0.5	-0.8
Worry too long after embarrassment	0.9	1.5	3.2	-1.8	0.9	0.8	0.9	-1.8	0.7	1.7	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.1	-0.5	0.2	0.3	-0.6	1.0	0.6	-0.0	-0.3
Wheeze or whistling in the chest in last year	1.4	2.6	4.6	0.4	1.8	1.9	1.9	0.4	2.0	-1.1	2.1
Number of children fathered	0.6	0.7	1.9	0.9	-0.6	-0.6	-1.0	0.3	-0.3	-1.4	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.6	6.2	0.7	-0.9	-0.9	-0.0	-0.7	-1.0	-2.5	1.6
Age at first live birth	0.3	0.5	1.5	-0.7	0.6	0.5	0.4	0.5	0.1	1.1	1.2
Pulse wave peak to peak time	0.7	0.8	2.5	0.8	0.6	0.7	1.2	1.6	0.4	-0.4	0.7
Health satisfaction	1.1	1.4	3.2	0.4	-1.8	-1.8	-1.2	0.7	-1.6	-0.5	0.4
Shortness of breath walking on level ground	0.3	0.4	1.4	1.2	-0.7	-0.7	0.3	-0.1	-0.4	-0.2	-0.4
Qualifications: College or University degree	0.7	2.2	5.0	-2.0	1.1	1.1	-0.4	-0.6	1.4	-2.0	2.2
Eye problems/disorders: None of the above	0.2	0.2	0.6	-0.8	0.1	0.1	0.3	0.5	0.3	-0.4	0.4
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.5	1.1	-0.8	-0.8	-1.2	0.3	-0.8	-0.3	-0.4
Emphysema/chronic bronchitis	0.9	1.0	3.7	-0.5	0.8	0.8	1.0	1.0	0.5	0.6	1.9
Medication for pain relief, constipation, heartburn	4.9	8.4	15.5	-3.9	3.2	3.0	2.7	-2.3	2.6	3.0	1.8
Neck or shoulder pain in last month	3.0	4.2	9.0	1.5	-2.3	-2.3	-2.4	1.3	-1.9	-0.8	-3.0
Medication: Blood pressure	1.9	3.4	5.0	1.9	-2.1	-2.0	-2.2	-0.2	-2.2	-2.2	0.3
Angina (self-reported)	25.2	33.1	50.8	5.8	-7.1	-7.0	-5.9	3.3	-7.1	-4.6	-3.9
Migraine (self-reported)	1.5	1.8	3.8	1.6	-1.7	-1.7	-1.9	0.0	-1.3	-0.4	-0.8
Medication: Ibuprofen	0.9	1.1	2.4	0.6	0.8	0.9	1.5	1.2	1.1	0.0	1.4
Medication: Allopurinol	1.1	1.5	3.2	-0.8	1.7	1.8	0.9	-0.3	1.8	0.7	0.6
Medication: Omeprazole	0.7	0.9	2.0	0.2	-1.0	-1.0	-1.4	0.5	-1.1	-0.8	-0.8
Medication: Seretide 50 evohaler	1.6	1.8	3.6	-0.5	1.6	1.6	1.5	-1.9	1.5	0.5	0.9
Mean time to correctly identify matches	1.9	3.7	11.7	-1.4	1.5	1.4	1.7	-3.4	1.6	2.5	-0.1
Heart disease (mother)	1.7	2.0	3.9	1.1	-2.0	-1.9	-1.3	0.3	-1.9	-1.3	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.7	1.6	1.0	-0.6	-0.5	-0.0	1.3	-0.7	0.6	-1.1
Whole body fat mass	0.1	0.3	0.7	0.1	0.4	0.3	-0.8	-0.7	0.3	0.8	-0.7
Leg fat mass (right)	0.0	0.1	0.3	0.3	0.2	0.2	-0.5	-0.6	0.1	0.4	-0.0
Arm predicted mass (right)	2.6	13.4	21.3	-2.8	4.6	4.6	3.7	-0.5	4.5	1.9	4.4
Pulse rate, automated reading	2.0	6.5	13.5	2.4	-2.7	-2.6	-3.2	3.7	-2.4	-1.3	-1.3
Alcohol intake frequency.	0.2	0.4	0.6	0.7	-0.8	-0.8	0.7	-0.1	-0.7	-0.6	0.2
Comparative height size at age 10	1.6	9.0	15.7	-1.9	4.0	3.9	2.6	-0.8	3.9	3.7	-0.7
Number of full sisters	0.5	0.6	1.5	0.4	-0.6	-0.7	-0.7	-1.2	-0.5	0.5	-0.9
Suffer from ‘nerves’	0.2	0.4	1.4	-0.4	-0.1	-0.0	-0.4	0.9	-0.0	1.2	-0.6
Overall health rating	1.0	2.3	3.2	1.5	-1.7	-1.8	-1.8	-1.1	-1.6	-0.6	-1.6
Chest pain or discomfort	3.6	5.2	8.6	2.0	-2.6	-2.5	-2.9	1.5	-2.4	-2.4	-1.5
Had major operations	3.2	3.8	9.1	1.3	-2.0	-2.0	-3.0	0.7	-2.0	-1.5	-2.1
Age at last live birth	0.3	0.4	0.9	0.4	-0.6	-0.6	-0.6	0.3	-0.9	-0.3	1.0
Family relationship satisfaction	0.3	0.4	0.7	0.4	-0.7	-0.8	0.9	-0.7	-0.4	-0.0	0.8
Leg pain on walking	0.6	0.8	1.8	0.1	0.6	0.6	1.1	-0.9	0.8	1.4	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	4.0	1.4	-0.4	-0.4	-0.8	2.0	-0.2	0.3	-1.2
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.7	1.3	-0.4	-0.4	-1.2	-0.7	-0.5	-0.3	-1.2
Illness, injury, bereavement, stress in last 2 years	0.9	1.0	2.2	-1.3	0.8	0.7	-0.3	-1.3	0.4	1.5	-1.2
Medication: Aspirin	17.8	23.4	36.4	5.0	-6.0	-5.9	-4.7	1.6	-5.7	-5.1	-2.9
Supplements: Vitamin C	2.9	3.5	7.8	-1.3	2.0	1.9	2.8	-2.4	1.7	1.2	0.9
Knee pain experienced in last month	0.3	0.5	2.1	-1.2	0.4	0.3	0.4	-1.5	0.3	-0.0	-0.2
Hypertension (Self-reported)	0.5	1.3	7.1	-0.3	-0.2	-0.3	0.9	-2.7	-0.6	0.6	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.7	-1.2	0.0	-0.1	-0.3	0.4	-0.5	1.3	-0.1
Illnesses of father: Heart disease	19.8	27.4	47.2	2.9	-6.5	-6.5	-6.8	1.3	-6.9	-4.4	-3.6
Illnesses of siblings: Diabetes	1.1	1.4	4.9	-1.4	0.9	0.7	0.6	-2.2	0.9	0.7	-1.2
Smoking status: Previous	0.5	0.8	3.7	-0.5	-0.3	-0.3	0.3	1.0	-0.4	-0.8	1.9
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.4	7.9	0.0	2.4	2.5	1.8	0.8	2.8	0.4	1.9
Whole body fat-free mass	2.2	12.8	22.6	-2.6	4.7	4.8	3.4	-0.8	4.7	1.2	3.9
Leg fat-free mass (right)	1.5	7.9	14.7	-1.9	3.8	3.8	2.2	-0.3	3.7	0.8	3.4
Arm fat percentage (left)	0.3	1.0	3.6	0.5	-1.0	-1.0	-1.9	-0.4	-1.1	0.2	-0.9
Average weekly red wine intake	3.1	4.6	7.8	1.7	-2.2	-2.2	-2.5	0.1	-2.2	-2.8	-2.3
Handedness (chirality/laterality): Left-handed	0.7	0.8	3.0	0.5	0.6	0.7	-0.2	1.0	1.0	-1.7	0.5
Mood swings	0.9	1.7	4.8	-1.4	1.2	1.0	1.3	-1.3	0.6	2.2	0.4
Loneliness, isolation	0.1	0.2	0.5	-0.1	0.2	0.2	0.2	-0.5	0.5	-0.7	-0.7
Long-standing illness, disability or infirmity	0.8	1.3	2.9	1.1	-1.2	-1.1	-1.7	0.3	-0.7	-1.5	-0.9
Ever had bowel cancer screening	0.2	0.3	0.7	0.8	-0.3	-0.2	-0.5	-0.8	-0.3	0.6	0.2
Diabetes diagnosed by doctor	0.3	0.6	3.1	0.9	-0.2	-0.1	-1.8	-0.4	-0.1	-0.5	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	3.1	-0.5	0.6	0.5	-1.0	-1.7	0.1	1.1	-1.7
Friendships satisfaction	0.3	0.4	0.8	0.7	-0.8	-0.9	-0.3	0.2	-0.9	-0.7	-0.1
Qualifications: nursing, teaching	1.2	1.9	11.6	0.8	-0.6	-0.4	-0.9	-0.4	-0.3	-3.4	1.1
Commuting to job workplace: Walk	2.4	2.6	4.6	0.9	-2.2	-2.1	-0.8	1.3	-2.0	-1.7	1.2
Eye problems/disorders: Cataract	0.7	0.8	3.1	0.0	0.1	0.1	1.4	-1.2	-0.0	1.8	0.2
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	3.2	1.1	-0.6	-0.6	-0.6	1.8	-0.5	1.1	-0.9
Medication for cholesterol	9.2	14.0	25.1	-3.6	4.9	4.9	3.9	-0.2	5.0	2.1	2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.5	0.7	0.1	0.2	-0.7	0.3	-0.0	0.1	0.6
Back pain experienced in last month	0.7	1.0	4.5	-0.9	-0.3	-0.4	-0.9	-0.5	-0.5	1.0	-2.1
Mineral and other dietary supplements	0.5	0.7	3.0	0.6	-0.8	-0.6	-0.0	1.7	-1.0	0.6	0.2
Breast cancer (self-reported)	1.1	1.3	2.4	-0.2	-1.4	-1.4	-1.0	1.2	-1.1	-1.5	0.4
Asthma (self-reported)	0.6	1.2	4.4	-0.0	0.5	0.7	0.8	1.3	0.8	-1.1	2.1
Osteoporosis (self-reported)	0.3	0.4	0.8	0.7	-0.7	-0.8	-0.7	0.4	-0.9	-0.3	-0.3
Osteoarthritis (self-reported)	2.1	2.7	6.2	-1.5	2.3	2.4	1.5	-0.1	2.5	0.0	0.3
Medication: Aspirin	18.5	24.2	38.7	4.8	-6.2	-6.1	-4.9	1.5	-6.0	-4.8	-2.9
Medication: Gliclazide	1.7	1.9	6.2	1.3	-0.2	-0.0	-1.7	2.0	0.1	-2.5	-0.5
Illnesses of father: None of the above (group 1)	2.6	3.2	8.1	0.0	2.1	2.2	2.9	0.6	2.4	1.5	0.5
Smoking status: Current	2.7	4.3	6.7	-2.3	2.6	2.5	1.0	-2.2	2.6	1.8	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	3.0	9.8	0.8	-1.7	-1.6	-1.7	3.1	-2.2	-0.3	-0.2
Whole body water mass	2.1	12.1	21.3	-2.5	4.6	4.6	3.3	-0.7	4.5	1.1	3.9
Leg predicted mass (right)	1.5	7.8	14.7	-1.9	3.8	3.8	2.2	-0.2	3.7	0.9	3.3
Arm fat mass (left)	0.1	0.3	0.8	-0.3	0.4	0.4	-0.9	-0.7	0.2	0.8	0.2
Number of self-reported non-cancer illnesses	4.0	6.9	10.8	1.8	-3.3	-3.3	-2.8	-0.9	-3.1	-1.9	-3.0
Average weekly champagne plus white wine intake	0.6	0.9	2.3	-0.8	0.7	0.7	-0.2	-1.1	0.8	-1.5	1.0
Miserableness	0.3	0.6	2.1	-1.0	0.3	0.3	-0.4	1.4	0.1	1.0	-0.1
Guilty feelings	0.5	0.7	2.6	-1.6	-0.3	-0.3	0.2	-0.3	-0.6	-0.4	1.5
Wears glasses or contact lenses	0.7	0.9	4.3	-0.9	0.3	0.3	0.2	-1.0	-0.0	0.7	2.1
Ever taken oral contraceptive pill	0.3	0.4	2.1	-0.7	0.2	0.2	-0.3	0.3	0.3	-1.4	0.4
Hearing aid user	1.0	1.1	1.7	-1.3	1.2	1.2	1.0	-0.9	1.3	0.7	-0.3
Mother’s age at death	0.9	1.1	2.3	-1.2	1.2	1.1	0.4	-1.3	1.5	-0.2	0.4
Financial situation satisfaction	0.3	0.3	2.0	0.0	-0.2	-0.2	0.2	1.4	-0.2	0.5	0.3
Tinnitus: Yes, now most or all of the time	2.0	2.4	4.0	1.4	-1.8	-1.8	-2.0	0.2	-1.9	-1.6	0.3
Commuting to job workplace: Public transport	1.1	1.3	4.1	-0.2	0.4	0.4	1.7	1.2	0.4	1.1	2.0
Eye problems/disorders: Glaucoma	0.4	0.4	1.1	0.1	0.9	0.9	0.3	0.1	1.0	-0.2	-0.8
Medication: Blood pressure	0.5	0.9	5.8	0.1	-0.4	-0.5	0.4	-2.4	-0.9	-0.1	0.1
Pain type(s) experienced in last month: Hip pain	0.7	0.9	3.6	-1.1	0.7	0.6	0.9	-0.6	0.7	1.9	-0.3
Supplements: Fish oil (including cod liver oil)	1.5	1.9	3.8	-1.9	1.4	1.3	1.2	-1.8	1.2	1.3	0.6
High cholesterol (Self-reported)	116.0	205.7	357.2	11.8	-18.9	-18.7	-13.9	5.3	-18.5	-12.8	-8.5
Medication: Bendroflumethiazide	1.3	2.0	7.4	-1.8	1.0	1.0	1.1	-2.7	0.6	1.1	0.9
Medication: Paracetamol	0.4	0.7	2.5	1.0	-0.6	-0.5	-0.3	1.0	-0.3	-1.6	-0.3
Medication: Lisinopril	1.1	1.4	2.3	1.2	-1.5	-1.4	-0.7	0.4	-1.4	-1.1	1.1
Medication: Atorvastatin	55.5	68.6	118.8	7.2	-10.9	-10.8	-8.1	3.9	-10.9	-6.2	-4.8
Illnesses of father: High blood pressure	1.1	1.4	4.0	1.6	-0.7	-0.7	-1.4	0.9	-0.8	-2.0	0.5
Alcohol drinker status: Never	0.6	0.7	2.9	0.0	0.9	0.8	0.6	-1.7	0.9	-0.2	-0.2
Ever smoked	1.0	1.8	8.0	-0.9	0.9	0.8	1.3	-1.5	0.7	0.3	2.8
Basal metabolic rate	1.7	9.2	16.8	-2.1	4.0	4.1	2.7	-0.7	4.0	1.1	3.3
Leg fat percentage (left)	0.3	1.1	2.3	0.3	-1.0	-1.1	-1.1	-1.3	-1.1	0.7	-1.5
Arm fat-free mass (left)	2.0	10.0	17.0	-2.2	4.1	4.1	3.1	-1.0	4.0	1.7	3.4
Number of operations (self-reported)	0.7	1.0	2.4	1.6	-0.9	-0.9	-1.1	0.3	-0.5	-1.1	-1.2
Average weekly beer plus cider intake	0.3	0.4	1.8	-0.3	0.0	0.0	0.4	0.8	0.1	1.0	-1.4
Irritability	0.1	0.2	0.5	-0.6	-0.2	-0.2	-0.0	-0.4	-0.1	-0.7	0.4
Risk taking	2.6	3.8	6.1	-1.1	2.3	2.3	2.5	-1.9	2.1	1.6	1.5
Ever had prostate specific antigen (PSA) test	0.1	0.2	0.7	0.3	0.0	-0.0	-0.3	-0.9	0.1	0.6	0.2
Fractured/broken bones in last 5 years	0.1	0.2	0.6	0.7	-0.1	-0.1	0.2	-0.6	0.1	-0.1	-0.5
Age started oral contraceptive pill	1.1	1.4	4.5	-1.0	0.8	0.7	1.8	-2.1	0.7	1.0	-0.2
Diastolic blood pressure, automated reading	0.8	2.5	6.2	-2.5	1.7	1.6	1.1	-0.1	1.4	1.2	1.8
Ever depressed for a whole week	1.6	2.0	6.5	0.5	-1.1	-1.0	-1.6	1.9	-0.8	-2.5	-0.5
Unable to work because of sickness or disability	1.3	1.7	4.2	0.9	-1.8	-1.8	-1.2	-0.6	-2.1	0.1	-0.2
Commuting to job workplace: Cycle	0.8	1.0	4.3	0.6	0.6	0.7	1.4	0.5	0.7	-0.3	2.1
Myopia	0.3	0.4	1.3	-0.5	0.6	0.7	0.3	0.1	0.6	-0.8	1.2
Vascular/heart problems diagnosed by doctor	0.5	1.3	4.9	-0.5	1.1	1.2	0.1	2.2	1.6	0.1	-0.6
Cholesterol lowering medication	51.8	76.3	132.2	7.0	-11.5	-11.4	-8.6	2.8	-11.4	-6.9	-6.2
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	1.3	0.1	-1.1	-1.1	-1.0	-0.2	-1.1	-0.9	-1.0
Pain experienced in last month	0.3	0.5	2.5	0.8	0.1	0.1	0.6	0.2	-0.2	-0.7	1.6
Supplements: Calcium	0.6	0.6	1.8	-0.4	-0.6	-0.6	-1.2	1.4	-0.9	0.1	0.2
Basal cell carcinoma (self-reported)	0.2	0.2	1.1	-0.7	0.2	0.2	0.1	1.1	-0.2	0.1	-0.0
Heart attack/myocardial infarction (self-reported)	18.3	23.6	31.1	5.3	-5.6	-5.5	-5.2	1.4	-5.5	-4.8	-4.0
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.2	-1.0	0.9	0.9	1.5	0.7	1.1	1.1	0.4
Heart disease (siblings)	5.8	7.1	13.2	1.9	-3.6	-3.6	-2.5	1.5	-3.5	-1.2	-2.3
Alcohol drinker status: Previous	2.8	3.2	5.9	1.8	-2.4	-2.4	-1.1	-0.0	-1.9	-2.3	-0.3
Pack years of smoking	0.7	1.0	2.3	1.5	0.5	0.6	0.3	-1.1	0.6	1.3	-1.4
Impedance of whole body	2.1	10.5	40.3	2.3	-3.4	-3.5	-1.9	0.3	-3.2	0.6	-6.3
Leg fat mass (left)	0.0	0.2	0.6	-0.1	0.4	0.4	-0.4	-0.8	0.3	0.6	0.0
Arm predicted mass (left)	2.3	11.5	19.9	-2.4	4.4	4.5	3.4	-0.6	4.4	1.6	3.6