Best TWAS P=6.88e-15 · Best GWAS P=2.38e-24 conditioned to 2.5e-17
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | CPEB4 | 0.39 | 0.00 | lasso | 6 | 0.03 | 5.0e-02 | 5.1 | -5.5 | 4.8e-08 | 0.10 | 0.08 | 0.11 | FALSE |
| 2 | METSIM | Adipose | CPEB4 | 0.07 | 0.03 | bslmm | 661 | 0.04 | 3.1e-06 | 5.3 | 7.8 | 6.9e-15 | -0.26 | 0.95 | 0.01 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CPEB4 | 0.10 | 0.07 | lasso | 2 | 0.06 | 1.3e-08 | 6.1 | -5.7 | 1.0e-08 | 0.01 | 1.00 | 0.00 | FALSE |
| 4 | YFS | Blood | CPEB4 | 0.58 | 0.72 | bslmm | 632 | 0.73 | 0.0e+00 | 6.1 | 5.8 | 8.7e-09 | -0.05 | 1.00 | 0.00 | FALSE |