[Hub]/) : Traits : Heel T-Score : ← →

chr5:176,040,488-177,626,134

Best TWAS P=2.08e-14 · Best GWAS P=9.23e-11 conditioned to 0.346

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RAB24 0.14 0.06 enet 14 0.09 4.2e-11 -5.4 -7.3 4.0e-13 0.12 0.56 0.44 TRUE
2 GTEx Adipose Subcutaneous RP11-1277A3.3 0.11 0.06 enet 19 0.07 1.3e-06 5.0 -5.4 6.8e-08 0.64 0.15 0.75 FALSE
3 GTEx Artery Tibial DBN1 0.07 0.07 lasso 2 0.05 4.5e-05 5.1 -5.8 5.9e-09 0.77 0.05 0.94 TRUE
4 GTEx Muscle Skeletal PDLIM7 0.39 0.24 lasso 3 0.23 1.8e-22 5.1 5.2 2.3e-07 -0.68 0.84 0.16 FALSE
5 GTEx Nerve Tibial DOK3 0.17 0.10 enet 14 0.08 4.2e-06 3.6 5.3 9.1e-08 -0.40 0.90 0.08 FALSE
6 GTEx Nerve Tibial RP11-1334A24.6 0.19 0.00 enet 36 0.06 3.2e-05 3.6 7.7 2.1e-14 -0.34 0.09 0.07 TRUE
7 METSIM Adipose RAB24 0.05 0.02 lasso 4 0.02 1.2e-03 -5.4 -5.8 7.7e-09 0.06 0.32 0.41 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma DOK3 0.03 0.01 enet 10 0.02 4.6e-05 2.8 6.9 6.8e-12 -0.69 0.02 0.49 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma DOK3 0.04 0.01 enet 6 0.02 2.2e-03 2.8 5.6 1.7e-08 -0.70 0.01 0.66 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma RAB24 0.23 0.04 enet 19 0.06 6.5e-07 -5.4 -5.3 1.3e-07 0.00 0.00 0.97 FALSE