TWAS hub - RAB24

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1400	0.0400	2.6e-05	0.060	0.056	0.090	0.077	0.088	7.4e-08	2.0e-07	4.2e-11	1.1e-09	6.8e-11
2	GTEx	Adipose Subcutaneous	0.1690	0.0560	3.3e-05	0.081	NA	0.140	NA	0.106	3.9e-07	NA	1.7e-11	NA	5.4e-09
3	GTEx	Artery Tibial	0.1841	0.0585	8.5e-05	0.085	NA	0.073	NA	0.073	3.3e-07	NA	2.4e-06	NA	2.3e-06
4	GTEx	Cells EBV-transformed lymphocytes	0.3690	0.0810	1.9e-07	0.260	NA	0.218	NA	0.244	4.9e-09	NA	1.1e-07	NA	1.7e-08
5	GTEx	Nerve Tibial	0.2695	0.0801	7.8e-06	0.077	NA	0.167	NA	0.134	3.9e-06	NA	6.3e-12	NA	9.6e-10
6	METSIM	Adipose	0.0453	0.0208	2.3e-03	0.020	0.009	0.012	0.012	0.017	4.0e-04	1.4e-02	4.9e-03	4.8e-03	1.2e-03
7	YFS	Blood	0.1273	0.0354	2.3e-06	0.004	0.021	0.034	0.036	0.020	1.5e-02	1.1e-07	2.6e-11	4.8e-12	3.3e-07
8	TCGA	Colon Adenocarcinoma	0.0750	0.0540	4.1e-03	0.042	0.040	0.056	NA	0.045	1.9e-03	2.2e-03	3.4e-04	NA	1.3e-03
9	TCGA	Prostate Adenocarcinoma	0.2316	0.0891	6.5e-05	0.035	0.053	0.060	NA	0.025	1.2e-04	2.8e-06	6.5e-07	NA	9.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Height	20.1	387.6	639.5	25.3	23.1	23.8	-4.0	23.0	21.8	2.6	21.7	16.0
Standing height	17.5	173.6	294.9	17.2	14.8	16.1	-1.6	15.1	14.6	2.6	15.0	10.6
Forced expiratory volume in 1-second (FEV1), predicted	13.4	27.8	50.8	7.1	6.4	6.1	-0.4	6.8	5.6	0.9	5.0	4.1
Waist Hip Ratio (WHR)	10.7	48.2	110.2	10.5	6.6	7.7	6.5	4.6	9.6	2.6	3.7	6.7
Forced vital capacity (FVC), Best measure	9.7	35.5	57.7	7.1	6.7	7.1	-1.9	7.6	6.2	1.4	6.5	5.4
Comparative height size at age 10	9.7	53.3	94.3	9.7	8.1	8.6	-2.4	9.1	7.4	0.0	8.2	5.7
Forced vital capacity (FVC)	8.9	34.1	52.9	6.7	6.6	7.0	-2.0	7.3	6.2	1.7	6.8	5.0
Trunk predicted mass	7.4	42.2	67.9	7.2	7.5	7.8	-4.8	8.2	6.0	1.2	7.7	4.9
Trunk fat-free mass	7.3	41.9	67.0	7.2	7.5	7.8	-4.8	8.2	5.9	1.3	7.7	4.9
Forced expiratory volume in 1-second (FEV1), Best measure	6.9	21.9	32.3	5.5	5.1	5.3	-0.5	5.6	4.9	2.3	5.7	4.5
Arm fat-free mass (right)	6.0	30.9	46.9	6.2	6.4	6.8	-3.9	6.8	5.4	2.1	6.4	3.8
Arm predicted mass (right)	5.9	30.0	47.8	6.2	6.3	6.7	-3.8	6.9	5.3	2.1	6.2	3.7
Arm fat-free mass (left)	5.8	29.6	44.9	6.1	6.5	6.7	-3.5	6.6	5.4	2.0	6.2	3.9
Impedance of leg (left)	5.7	27.5	55.7	7.5	4.5	5.2	7.1	2.6	6.8	2.9	3.8	4.3
Forced expiratory volume in 1-second (FEV1)	5.7	19.3	29.2	5.2	4.6	5.1	-0.0	4.9	4.9	2.3	5.4	4.0
Arm predicted mass (left)	5.7	28.7	43.0	6.1	6.4	6.5	-3.6	6.6	5.1	1.9	6.2	3.9
Impedance of leg (right)	5.3	25.8	54.5	7.4	4.1	5.0	7.1	2.6	6.6	2.8	3.5	4.1
Whole body fat-free mass	5.1	29.2	50.1	5.8	6.2	6.3	-4.8	7.1	4.7	1.3	6.3	3.8
Chronic bronchitis/emphysema (father)	5.0	5.8	9.8	2.5	2.8	3.1	-1.4	3.1	2.7	-0.8	2.4	1.9
Whole body water mass	5.0	28.5	49.0	5.7	6.1	6.3	-4.7	7.0	4.7	1.1	6.2	3.8
Blood clot in the leg (DVT)	4.4	5.7	11.5	2.6	2.1	3.3	1.5	2.0	3.4	1.1	2.2	2.2
Basal metabolic rate	4.4	24.2	40.4	5.5	5.7	5.8	-4.1	6.4	4.4	1.6	5.6	3.3
Number of self-reported non-cancer illnesses	4.3	7.5	20.3	-1.6	-3.1	-2.3	2.6	-3.3	-1.7	1.0	-4.5	-2.8
Pulse wave peak to peak time	4.0	4.7	8.9	1.5	3.0	2.0	-2.6	2.8	1.5	-1.2	2.8	1.2
Supplements: Vitamin C	3.9	4.6	9.6	-2.3	-3.1	-2.7	1.7	-2.2	-2.1	0.1	-2.1	-1.5
Deep venous thrombosis (DVT) (self-reported)	3.1	4.0	8.0	2.1	1.8	2.7	1.5	1.7	2.8	0.9	1.7	1.9
Allergy or Eczema	3.0	7.9	28.6	-1.6	-3.5	-2.3	1.2	-2.9	-1.8	-0.1	-5.3	-2.9
Frequency of tenseness / restlessness in last 2 weeks	3.0	4.7	11.1	2.2	3.3	2.4	0.4	2.2	2.3	2.2	1.6	1.8
BMI	2.9	16.6	28.5	-5.3	-4.3	-5.1	-1.3	-3.9	-5.2	0.7	-4.3	-3.9
Medication: Ibuprofen (e.g. Nurofen)	2.9	3.6	7.3	1.5	1.0	2.1	2.7	0.8	2.7	1.5	1.5	2.4
Loud music exposure frequency	2.9	3.1	5.4	-2.0	-2.1	-2.0	0.5	-1.5	-2.2	-0.2	-2.3	-1.7
Impedance of whole body	2.9	14.8	43.0	5.5	2.7	3.2	6.6	1.4	4.8	1.8	2.4	2.9
Alzheimer’s Disease (in father)	2.8	3.0	10.4	1.2	0.8	1.8	1.4	0.1	2.0	3.2	1.7	1.7
Medication: Ventolin 100micrograms inhaler	2.8	3.5	6.9	-1.8	-2.0	-2.1	-0.4	-1.3	-2.1	1.8	-2.6	-2.1
Weight	2.7	13.1	20.9	4.6	4.3	4.3	-1.9	4.1	3.7	2.5	3.8	2.2
Heel T-Score	2.6	20.9	52.7	-7.3	-4.1	-4.6	-3.3	-3.3	-5.8	0.1	-3.9	-5.3
Medication: Omeprazole	2.6	3.1	6.8	1.2	2.0	1.9	-2.6	2.0	1.1	-1.4	1.9	1.0
Basal cell carcinoma (self-reported)	2.6	3.0	5.8	2.4	2.0	2.0	0.7	2.1	1.9	0.4	1.9	0.9
Blood Eosinophil Count	2.5	19.2	66.9	-4.0	-4.3	-4.6	1.4	-3.9	-3.7	-2.3	-8.2	-3.6
Number of incorrect matches in round	2.5	4.2	7.0	1.6	2.2	2.6	-2.2	1.8	1.6	-0.2	2.7	2.3
Blood Red Count	2.4	23.2	76.0	-3.6	-6.3	-4.0	1.1	-4.5	-3.4	-2.5	-8.7	-5.0
Average weekly fortified wine intake	2.4	2.8	10.2	-0.4	-1.1	-0.3	2.9	-2.0	0.3	3.2	-0.4	-0.8
Medication: Paracetamol	2.4	4.0	10.9	1.4	0.5	2.2	2.7	0.2	2.8	3.3	1.1	1.2
Gout (self-reported)	2.4	3.2	8.5	-0.5	-1.8	-1.3	2.9	-2.7	-0.5	0.3	-2.6	-1.2
Number of operations (self-reported)	2.4	3.6	7.6	2.8	1.5	2.2	0.9	2.0	2.3	0.2	1.9	2.0
Hand grip strength (left)	2.3	6.0	10.5	2.4	3.1	3.2	-1.5	2.4	2.8	0.1	2.7	2.4
Maternal smoking around birth	2.3	3.3	8.2	2.2	0.4	1.7	2.3	0.9	2.4	2.9	1.1	0.8
Leg predicted mass (left)	2.3	11.9	23.3	3.5	3.8	3.7	-4.3	4.8	2.5	1.0	3.8	1.9
Allergy	2.3	5.4	16.4	1.7	3.2	1.4	-0.8	2.4	1.1	-1.2	4.0	2.8
Back pain experienced in last month	2.3	3.3	10.3	2.1	1.1	1.6	2.0	0.9	2.1	3.2	1.1	1.0
Smoking status: Current	2.3	3.7	9.1	1.5	3.0	1.5	-1.2	3.0	1.0	-0.9	2.0	1.9
Leg predicted mass (right)	2.3	12.1	23.9	3.1	3.8	3.7	-4.9	4.9	2.2	0.6	3.8	1.8
Diabetes (father)	2.2	2.7	5.2	-2.0	-1.2	-2.2	-0.2	-1.0	-2.0	-1.4	-2.3	-1.4
Bilateral oophorectomy (both ovaries removed)	2.2	2.6	5.5	1.4	1.6	1.8	1.5	0.5	1.9	0.9	2.3	1.6
Hayfever, allergic rhinitis or eczema	2.2	4.7	15.8	-1.3	-3.0	-1.4	1.2	-2.3	-1.0	0.6	-4.0	-2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.2	2.6	5.3	-1.7	-1.4	-2.3	-0.5	-1.2	-2.1	-1.3	-2.2	-0.6
Leg fat-free mass (right)	2.2	11.8	23.4	3.1	3.8	3.6	-4.8	4.8	2.2	0.7	3.8	1.8
Cardiovascular Disease	2.1	7.1	39.8	0.6	-1.9	-1.0	6.3	-2.7	1.0	0.5	-3.3	0.2
Type 2 Diabetes (T2D) (2018)	2.1	3.9	6.6	-2.6	-2.0	-2.1	-1.4	-1.3	-2.2	-1.8	-2.3	-1.6
Leg fat-free mass (left)	2.1	11.2	22.5	3.4	3.6	3.6	-4.2	4.7	2.3	1.0	3.6	1.8
Heel bone mineral density (BMD) T-score, automated (right)	2.1	4.8	10.7	-3.3	-2.2	-1.8	-1.3	-2.0	-2.5	-0.1	-1.7	-3.1
Pulse wave reflection index	2.1	2.6	7.5	-0.5	-1.9	-1.0	2.7	-1.9	-0.9	2.1	-1.2	-0.8
Alcohol usually taken with meals	2.0	3.2	6.8	-2.3	-1.8	-1.9	0.3	-2.6	-1.8	-1.2	-1.3	-1.6
Had menopause	2.0	2.5	5.8	2.2	2.4	1.9	1.0	0.3	2.1	-0.5	1.3	0.9
Exposure to tobacco smoke at home	2.0	2.2	8.6	-0.4	-1.2	-0.7	1.8	-1.5	-0.2	2.9	-1.7	-1.1
Medication: Amlodipine	2.0	2.8	6.1	-2.5	-2.2	-1.1	-0.2	-1.8	-1.3	-1.4	-1.5	-1.9
Financial situation satisfaction	2.0	2.5	5.0	1.0	1.6	1.7	0.3	0.9	1.4	2.1	2.2	2.0
Pack years of smoking	2.0	2.9	5.5	2.4	1.3	2.2	1.2	1.3	2.3	1.9	0.9	1.1
Fasting Glucose	1.9	2.3	5.5	1.3	1.3	1.9	2.3	0.3	2.1	1.0	1.2	0.9
Neuroticism (2016)	1.9	2.8	7.3	2.7	1.6	1.9	-0.3	2.1	1.8	1.3	1.4	0.8
Hand grip strength (right)	1.9	5.1	8.5	2.3	2.8	2.7	-1.8	2.9	2.1	0.2	2.6	1.6
Medication: Blood pressure	1.9	3.6	9.3	-0.9	-1.8	-1.2	3.0	-2.4	-0.3	-1.1	-3.0	-1.1
Depression (Nagel 2018)	1.8	2.6	15.7	1.2	0.9	0.5	2.0	-0.6	1.0	4.0	-0.1	0.2
Triglycerides	1.8	2.9	7.6	0.0	-2.0	-1.3	1.3	-2.7	-1.2	-1.1	-1.7	-2.4
Pulse wave Arterial Stiffness index	1.8	2.0	6.3	-0.3	-2.0	-0.8	2.5	-1.7	-0.4	1.2	-1.7	-0.3
Hypertension (Self-reported)	1.8	5.1	25.1	0.5	-1.7	-0.6	5.0	-2.6	0.8	-0.4	-3.0	-0.7
Breast cancer (self-reported)	1.8	2.2	4.5	-2.1	-1.7	-1.4	-1.1	-1.0	-1.5	1.3	-1.6	-1.4
Unable to work because of sickness or disability	1.8	2.3	4.5	1.4	2.1	1.3	-1.3	1.9	1.1	-1.3	1.2	1.6
Lupus	1.7	2.5	5.1	1.5	1.7	1.7	-1.8	2.3	1.5	-0.3	1.2	1.8
Primary Biliary Cirrhosis	1.7	2.5	4.3	-1.8	-1.7	-1.4	0.5	-2.1	-1.5	0.4	-2.0	-1.9
Sitting height	1.7	12.1	38.6	3.4	3.4	3.7	-2.7	4.4	2.1	1.4	6.2	0.6
Arm fat percentage (right)	1.7	6.6	12.4	-2.2	-2.5	-3.5	1.0	-3.1	-2.7	1.5	-3.2	-2.2
Asthma	1.7	3.4	6.1	-2.0	-2.2	-1.3	-1.5	-1.4	-1.8	-0.8	-2.5	-2.3
Number of children fathered	1.7	1.9	3.5	1.7	1.0	1.7	1.5	0.5	1.9	1.6	1.2	0.6
Arm fat percentage (left)	1.7	6.8	11.4	-2.3	-2.7	-3.4	0.9	-3.1	-2.6	1.8	-3.3	-2.4
Asthma (self-reported)	1.7	3.5	6.2	-2.0	-2.3	-1.4	-1.3	-1.5	-1.9	-0.6	-2.5	-2.5
Current tobacco smoking	1.6	2.6	6.9	1.5	2.6	1.2	-0.5	2.6	0.8	-0.1	1.6	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	10.9	1.4	0.8	0.6	1.5	0.4	1.3	3.3	0.1	0.9
Body mass index (BMI)	1.6	6.9	11.0	-3.3	-2.4	-3.1	-1.4	-2.6	-3.0	1.3	-2.9	-2.7
Birth weight	1.6	3.4	11.4	1.4	1.7	1.0	-3.4	2.7	0.1	-1.0	2.2	0.7
Medication: Ibuprofen	1.6	1.9	4.9	1.0	0.6	1.2	2.1	0.6	1.7	0.9	0.9	2.2
Heart disease (mother)	1.6	1.9	5.5	-0.9	-1.3	-0.9	0.7	-1.4	-0.6	1.7	-2.3	-1.7
Hearing aid user	1.6	1.8	3.8	-0.2	1.6	0.5	-1.6	1.6	0.0	-1.9	1.9	0.8
Supplements: Calcium	1.6	1.8	5.7	-1.0	-1.3	-0.8	2.4	-1.9	-0.0	0.1	-1.5	-1.1
Vitamin and mineral supplements	1.5	2.1	5.3	1.4	1.8	2.3	-1.1	1.1	1.4	0.1	1.8	0.5
Diabetes (mother)	1.5	1.9	4.1	-2.0	-1.9	-1.4	-0.4	-0.9	-1.7	0.2	-1.1	-1.7
Pack years adult smoking proportion	1.5	2.3	4.7	2.2	1.2	1.9	1.4	1.1	2.0	1.8	0.5	0.9
Hearing difficulty/problems with background noise	1.5	2.4	11.4	-0.4	1.7	1.7	-3.4	1.1	0.6	0.9	1.5	-0.2
Migraine (self-reported)	1.5	1.8	4.7	-0.5	-1.5	-1.4	1.7	-1.2	-0.5	-1.7	-2.2	-0.2
Illnesses of father: Heart disease	1.5	2.0	3.8	-1.1	-1.8	-1.4	1.5	-2.0	-0.8	0.9	-1.9	-1.0
Medication: Gliclazide	1.5	1.7	6.0	-1.2	-0.8	-0.9	-1.9	-0.6	-1.1	-2.4	-0.6	-0.8
Medication: Paracetamol	1.5	2.3	4.7	1.5	0.7	1.7	1.6	1.1	1.9	2.2	1.2	1.3
Medication: Omeprazole (e.g. Zanprol)	1.5	1.8	3.4	0.8	1.6	1.6	-1.9	1.4	0.9	-0.7	1.8	0.6
Bipolar Disorder (2018)	1.4	2.2	5.0	0.0	-2.2	-1.6	0.9	-1.8	-1.2	1.2	-1.5	-1.5
Schizophrenia vs Biploar Disorder	1.4	1.8	4.0	0.0	0.0	1.7	0.6	1.2	1.8	-1.3	1.6	2.0
Ulcerative Colitis	1.4	2.1	6.7	0.0	-1.7	-1.8	-0.3	-1.0	-1.6	-0.1	-2.6	-1.4
Smoking Status	1.4	3.5	9.7	0.5	2.7	0.6	-1.9	3.1	-0.1	-2.2	2.0	1.0
Respiratory disease	1.4	3.1	8.3	-1.6	-2.2	-0.9	-1.3	-0.6	-1.5	-0.4	-2.6	-2.9
Neuroticism	1.4	3.5	7.0	2.6	2.1	2.2	0.4	2.0	2.0	2.2	1.1	0.7
High blood pressure	1.4	3.8	18.0	0.5	-1.5	-0.2	4.2	-2.4	0.9	-0.2	-2.6	-0.9
Headache pain in last month	1.4	2.4	12.0	1.8	-0.1	0.6	3.5	0.0	1.5	1.4	-1.3	0.0
Medication for cholesterol	1.4	2.1	4.1	1.1	2.0	0.9	-2.0	1.9	0.4	0.8	2.0	1.0
Osteoporosis (self-reported)	1.4	1.7	2.7	1.6	1.2	1.4	1.2	0.9	1.6	-0.3	1.3	1.6
Wears glasses or contact lenses	1.4	1.6	4.1	-1.5	-1.1	-1.4	0.3	-2.0	-0.9	0.5	-0.7	-1.8
Commuting to job workplace: Public transport	1.4	1.7	2.5	-1.1	-1.2	-1.5	0.2	-1.6	-1.1	-1.5	-1.5	-1.3
Diastolic blood pressure, automated reading	1.4	4.4	10.9	-1.2	-2.1	-1.6	2.7	-3.0	-0.6	1.6	-3.3	-1.3
Pain experienced in last month	1.4	2.4	4.9	-2.2	-0.5	-1.3	-2.2	-0.7	-1.9	-2.0	-0.2	-1.3
Alzheimer’s Disease (in mother)	1.3	1.6	3.3	-1.8	-0.9	-1.1	-1.1	-0.5	-1.7	-1.7	0.3	-1.1
Type 2 Diabetes (T2D) (2012)	1.3	1.5	4.0	0.0	0.0	0.0	0.0	0.0	-2.0	-1.8	-1.9	-1.5
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	6.0	-0.7	-1.6	-0.4	0.1	-1.6	-0.4	0.5	-2.4	-1.7
Medication: Co-codamol	1.3	1.5	5.6	-1.5	-0.8	-1.0	-2.4	0.1	-1.5	-1.3	0.1	-0.2
Waist circumference	1.3	4.9	10.6	3.2	2.3	2.5	0.9	1.5	2.8	3.0	0.9	1.2
Pain all over the body in last month	1.3	1.4	4.1	1.0	1.2	0.9	-0.7	2.0	0.8	-1.2	1.1	1.1
Worrier / anxious feelings	1.3	2.5	4.5	2.1	1.9	1.9	-0.4	1.3	1.8	0.6	1.9	1.4
Hair/balding pattern: Pattern 4	1.3	3.2	4.9	2.0	2.2	2.2	1.2	0.9	2.1	2.1	2.0	-0.5
Ever had bowel cancer screening	1.3	1.6	4.2	-1.4	-1.5	-0.7	-0.6	-2.1	-0.8	-0.5	-1.2	-1.5
Taking other prescription medications	1.2	1.8	5.6	-0.9	-1.8	-0.8	-1.1	-0.1	-1.1	0.5	-1.8	-2.4
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	5.1	0.1	0.9	0.3	-2.2	1.9	-0.0	-1.1	0.8	0.4
High blood pressure (mother)	1.2	1.6	6.4	-0.0	-1.3	-1.0	2.5	-1.3	0.0	0.4	-1.9	0.0
Peak expiratory flow (PEF)	1.2	2.9	6.2	2.5	1.1	1.8	0.6	1.5	2.1	1.1	1.7	2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	3.7	-1.3	-1.4	-1.2	-0.4	-0.9	-1.3	1.3	-0.9	-1.9
Medication for pain relief, constipation, heartburn	1.2	2.0	5.8	-1.2	0.3	-1.6	-2.4	0.2	-2.3	-0.9	-0.4	-1.4
Miserableness	1.2	2.1	6.8	2.2	0.3	0.4	2.6	0.3	1.2	2.1	-0.8	0.0
Rheumatoid Arthritis	1.1	1.6	7.7	0.0	0.1	-0.0	2.8	-1.0	0.5	0.9	-2.1	-0.2
Trunk fat mass	1.1	4.6	11.8	3.4	2.2	2.0	0.7	1.6	2.3	3.0	1.5	0.8
Diabetes (self-reported)	1.1	1.6	4.3	-1.3	-1.2	-1.2	-1.3	-0.3	-1.3	-2.1	-0.8	-1.3
Impedance of arm (right)	1.1	5.0	29.4	2.9	0.6	0.5	5.4	-0.1	2.0	-0.4	0.4	1.6
Father’s age at death	1.1	1.5	4.0	-2.0	-0.4	-1.1	-1.4	-1.1	-1.3	-0.2	-0.9	-1.5
Depression (self-reported)	1.1	1.3	5.7	0.0	0.5	-0.2	-2.4	0.5	-1.2	0.4	0.8	-1.8
Birth weight of first child	1.1	1.9	5.4	0.8	1.3	1.4	-2.3	2.0	0.7	0.1	1.4	1.1
Comparative body size at age 10	1.1	2.9	8.3	-1.5	-1.0	-2.9	0.7	-0.9	-2.2	-2.1	-2.1	0.1
Age at first live birth	1.1	1.9	3.5	0.8	0.9	1.7	-1.9	0.8	0.9	-1.8	1.7	1.2
Eye problems/disorders: None of the above	1.1	1.2	2.8	-1.1	-1.7	-1.1	0.6	-1.0	-0.8	-0.4	-1.5	-1.1
Emphysema/chronic bronchitis	1.1	1.2	3.8	1.1	1.2	1.3	0.1	0.8	1.4	2.0	0.3	0.2
Neck or shoulder pain in last month	1.1	1.6	10.7	0.3	-0.9	-0.1	1.4	-0.4	0.2	3.3	-0.1	-0.6
Age at last live birth	1.1	1.6	3.7	0.4	1.2	1.9	-1.4	0.5	1.3	0.6	1.9	1.0
Illnesses of siblings: Diabetes	1.1	1.4	3.1	1.5	1.4	1.1	-0.5	1.8	1.5	0.2	0.4	1.0
Mood swings	1.1	2.0	7.8	1.0	-0.3	-0.9	2.8	-0.4	-0.1	1.8	-2.1	0.1
Loneliness, isolation	1.1	1.5	5.9	-0.2	-0.7	-1.6	1.6	-1.2	-0.3	-0.8	-2.4	-0.1
Eye problems/disorders: Cataract	1.1	1.3	2.3	1.2	1.5	1.3	-0.1	1.2	1.2	0.8	1.5	0.9
Pain type(s) experienced in last month: Hip pain	1.1	1.4	3.8	-0.6	-0.5	-0.9	-1.9	1.0	-1.4	1.9	-0.8	-0.7
Major Depression (MDD)	1.0	1.2	2.4	0.0	-1.1	-1.5	0.3	-0.5	-1.4	1.3	-1.5	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	5.6	-2.4	-1.0	-1.2	-1.6	-1.0	-2.0	-0.0	-0.4	-2.2
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	3.7	-0.8	-1.3	0.1	1.5	-1.0	-0.0	1.1	-1.9	-1.4
Number of live births	1.0	1.4	3.0	1.2	1.5	1.7	-0.1	1.3	1.5	1.0	0.9	0.3
Impedance of arm (left)	1.0	4.6	23.7	3.0	0.6	0.9	4.9	0.3	2.2	0.3	0.7	1.3
Length of working week for main job	1.0	1.1	4.8	0.1	1.5	0.7	-0.7	0.7	0.3	-2.2	0.9	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	3.0	0.6	1.7	1.3	-1.3	1.5	0.8	0.0	0.8	0.5
Risk taking	1.0	1.4	6.2	0.1	-0.8	-1.4	2.5	-1.1	-0.6	0.1	-1.3	-0.8
Heart disease (siblings)	1.0	1.2	5.7	0.1	-0.8	-0.5	1.2	-0.7	0.0	1.2	-2.4	-0.8
Neuroticism (Nagel 2018)	0.9	2.0	6.1	2.5	1.7	1.1	1.1	0.8	1.6	1.8	0.1	0.8
Ulcerative Colitis (UC)	0.9	1.7	8.1	-0.0	-1.4	-1.3	-0.2	-0.2	-1.0	-1.2	-2.8	-0.8
Medication: Metformin	0.9	1.3	3.0	-0.8	-0.7	-1.1	-1.2	0.1	-1.2	-1.7	-1.3	-1.3
Illnesses of mother	0.9	1.1	3.4	0.3	0.9	0.8	-1.4	0.8	0.5	-0.1	1.8	1.3
High blood pressure (siblings)	0.9	1.4	7.4	0.2	-0.3	-0.8	2.7	-1.0	0.3	0.7	-1.6	-0.0
Medication: Allopurinol	0.9	1.2	6.0	0.1	-0.8	-0.1	2.5	-1.5	0.3	0.5	-1.2	0.1
Overall health rating	0.9	1.9	12.6	1.2	0.6	0.8	0.5	0.7	0.8	3.6	-0.4	-0.4
Diabetes diagnosed by doctor	0.9	1.4	3.8	-1.4	-1.0	-0.9	-1.5	-0.3	-1.1	-2.0	-0.9	-0.9
Medication: Aspirin	0.9	1.2	2.7	0.0	-1.6	-0.7	1.0	-1.6	-0.2	-1.0	-1.3	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	2.0	4.7	0.7	1.6	1.5	-1.5	1.8	1.1	0.5	2.2	1.1
Guilty feelings	0.9	1.4	9.4	0.0	0.1	0.0	0.6	-0.4	0.3	3.1	-0.8	-1.4
Medication: Lisinopril	0.9	1.2	2.6	-0.5	-1.1	-1.3	0.4	-0.8	-0.9	-1.6	-1.4	-1.3
Heart attack/myocardial infarction (self-reported)	0.9	1.1	2.5	1.3	1.0	0.3	-0.8	1.4	0.3	-1.1	1.6	1.1
Schizophrenia (2018)	0.8	1.6	3.7	0.0	1.7	1.1	0.9	0.7	1.4	-1.3	1.1	1.9
Breast Cancer	0.8	2.0	4.6	2.1	0.2	1.6	1.8	0.7	1.8	-0.0	1.4	1.3
Blood White Count	0.8	6.0	17.8	-3.2	-2.5	-1.7	-1.6	-0.8	-2.1	-0.4	-4.2	-3.0
Supplements: Zinc	0.8	0.9	2.3	-0.9	-1.5	-1.1	0.3	-0.7	-0.9	0.8	-1.0	-0.7
Financial difficulties in last 2 years	0.8	1.0	4.3	0.7	-0.0	-0.1	2.1	0.4	0.4	2.0	0.3	0.6
Heart attack	0.8	1.0	2.0	1.0	0.9	0.2	-0.9	1.1	0.1	-1.2	1.4	1.2
Leg fat percentage (right)	0.8	3.0	13.0	0.8	-0.3	-0.2	2.7	-1.9	0.7	3.6	-1.3	-0.7
Wheeze or whistling in the chest in last year	0.8	1.5	4.1	1.4	0.1	1.5	-0.4	1.2	1.2	2.0	-1.4	-0.3
Health satisfaction	0.8	1.0	3.8	1.1	0.6	0.8	0.7	-0.1	1.1	2.0	0.9	0.7
Medication: Blood pressure	0.8	1.4	5.3	0.3	-1.1	-1.0	2.3	-1.4	-0.1	-0.4	-1.3	-1.0
Leg fat mass (right)	0.8	3.0	9.9	2.5	1.7	1.6	0.6	0.9	1.9	3.1	0.7	0.6
Chest pain or discomfort	0.8	1.2	4.1	0.9	0.8	1.0	-0.3	1.3	1.0	2.0	1.1	0.4
Leg pain on walking	0.8	1.0	2.4	-1.2	-0.4	-0.7	-1.5	0.6	-1.3	-0.3	-0.4	-1.5
Commuting to job workplace: Walk	0.8	0.8	1.7	-1.0	-1.0	-1.2	-0.6	-0.2	-1.3	-0.8	-1.2	-0.0
Mother’s age at death	0.8	1.0	4.6	-1.1	0.2	-0.1	-0.9	-0.6	-0.6	-2.2	1.1	0.8
Leg fat percentage (left)	0.8	3.0	13.7	0.7	-0.1	-0.2	2.6	-1.9	0.8	3.7	-1.1	-0.5
Irritability	0.8	1.3	7.8	0.1	0.1	0.1	1.7	-0.3	0.2	2.8	-0.3	-0.9
Vascular/heart problems diagnosed by doctor	0.8	2.2	10.9	-0.7	1.1	0.1	-3.3	1.6	-0.8	0.3	2.0	0.6
Depressed Affect (Nagel 2018)	0.7	1.5	4.7	1.8	0.7	0.0	2.2	0.2	0.8	1.4	-1.2	0.7
Intelligence (Savage-Jansen 2018)	0.7	2.0	4.9	2.1	0.9	1.6	1.9	-0.0	2.2	1.0	0.4	1.0
HDL Cholesterol	0.7	1.1	3.3	0.0	1.0	0.7	-1.8	1.2	0.5	-0.7	1.5	0.9
Schizophrenia (2014)	0.7	1.5	3.4	0.0	1.7	1.3	0.0	0.7	1.3	-1.0	1.8	1.5
Lung FEV1/FVC ratio	0.7	3.6	11.5	0.1	-0.1	-0.0	3.1	-1.5	1.0	3.4	2.8	0.5
Frequency of depressed mood in last 2 weeks	0.7	1.0	5.6	0.7	0.5	0.0	1.3	-0.6	0.3	2.4	-0.5	0.3
Ever had hysterectomy (womb removed)	0.7	0.8	4.8	-0.1	0.3	-0.2	2.2	-0.9	0.5	-0.6	-0.8	0.5
Qualifications: CSEs or equivalent	0.7	1.0	1.6	-1.0	-1.3	-1.2	0.9	-0.2	-1.3	0.9	-1.3	-0.1
Stomach or abdominal pain in last month	0.7	0.8	3.0	1.7	0.4	0.5	0.3	1.4	0.8	0.3	0.2	1.2
Time employed in main current job	0.7	0.8	1.6	0.4	0.4	1.3	-1.2	1.0	0.4	1.1	1.2	0.1
Medication: Lansoprazole	0.7	0.8	2.0	-0.3	0.7	0.7	-1.3	1.0	0.1	1.4	0.5	-1.2
Exposure to tobacco smoke outside home	0.7	1.0	2.0	0.9	0.8	1.4	0.7	0.6	1.3	0.3	1.0	1.4
Shortness of breath walking on level ground	0.7	0.8	5.9	0.1	0.1	0.8	0.0	-0.3	0.8	2.4	-0.1	0.2
Whole body fat mass	0.7	2.9	8.2	2.7	1.7	1.4	0.6	1.0	1.7	2.9	0.9	0.4
Medication: Aspirin	0.7	0.9	2.6	-0.0	-1.4	-0.5	1.0	-1.6	-0.1	-0.9	-0.9	-0.9
Qualifications: nursing, teaching	0.7	1.1	4.7	-0.6	-0.2	0.4	-2.2	-0.8	-0.4	-0.1	1.7	-1.1
Alcohol drinker status: Never	0.7	0.9	2.0	1.1	0.4	0.7	1.3	0.2	1.4	1.4	-0.6	-0.5
Age started oral contraceptive pill	0.7	0.9	3.1	0.8	0.2	1.2	1.2	-0.8	1.8	0.5	0.1	0.5
Leg fat mass (left)	0.7	2.7	11.1	2.3	1.5	1.4	0.5	0.8	1.6	3.3	0.6	0.5
Irritable Bowel Disease (IBD)	0.6	1.5	6.2	-0.1	-0.9	-0.9	-0.7	0.2	-0.9	-1.6	-2.5	-1.2
Number of treatments/medications taken	0.6	1.2	4.2	0.1	-1.3	-0.7	1.5	-0.6	-0.1	0.6	-2.1	-1.0
Sensitivity / hurt feelings	0.6	1.0	2.7	1.6	1.0	1.4	0.0	0.3	1.4	1.0	0.6	0.4
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.3	1.1	0.6	0.6	0.3	0.7	0.9	-1.5	-0.1	0.2
Supplements: Glucosamine	0.6	0.8	2.0	-1.0	-0.8	-0.8	0.9	-1.1	-0.6	1.4	-0.7	-0.4
Hair/balding pattern: Pattern 2	0.6	0.8	2.8	0.4	-0.7	-0.3	1.7	-1.3	0.1	0.2	-1.4	0.3
Medication: Ramipril	0.6	0.7	1.4	-0.2	-1.1	-0.8	1.2	-0.9	-0.6	-0.5	-1.2	-0.7
Illnesses of siblings	0.6	0.8	3.1	-0.5	-0.1	0.3	-1.7	-0.2	-0.3	-0.9	1.8	0.2
Neuroticism score	0.6	1.2	3.6	1.5	1.2	1.0	0.5	0.8	1.1	1.9	0.1	0.2
Hair/balding pattern: Pattern 3	0.6	0.9	3.2	-1.4	-0.4	-0.1	-1.8	0.3	-0.9	0.1	1.2	-0.6
Prospective memory result	0.6	0.8	4.9	-0.1	0.0	0.7	-0.7	-0.0	0.1	2.2	1.1	0.0
Breastfed as a baby	0.6	0.8	1.7	-1.1	-1.0	-0.6	-0.7	-0.7	-0.7	1.0	0.0	-1.3
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	3.9	-0.5	1.2	0.9	-2.0	0.9	0.1	0.1	1.0	0.7
Body fat percentage	0.6	2.3	9.2	0.7	-0.4	-0.8	2.3	-1.6	0.2	3.0	-1.2	-1.0
Worry too long after embarrassment	0.6	1.1	2.3	1.5	1.0	1.4	0.6	0.5	1.5	1.2	0.3	0.6
Mean time to correctly identify matches	0.6	1.2	3.2	-0.1	1.6	1.1	-1.8	0.9	0.4	-1.0	1.4	-0.4
Had major operations	0.6	0.7	3.6	0.7	-0.5	-0.1	0.8	0.5	0.2	-1.1	-0.3	1.9
Knee pain experienced in last month	0.6	0.9	2.9	-0.0	-0.9	0.4	0.5	-1.3	0.5	1.7	-1.3	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.6	1.0	-0.4	1.1	1.0	-0.3	1.3	1.1	0.4	0.6
Average weekly champagne plus white wine intake	0.6	0.8	2.5	1.1	1.3	0.0	-0.5	0.8	0.1	-1.6	-0.3	0.7
Medication: Bendroflumethiazide	0.6	0.9	3.8	1.0	1.1	0.1	1.9	-0.4	0.9	0.2	-0.1	1.2
Illnesses of father: High blood pressure	0.6	0.8	2.2	-0.9	-0.8	-0.8	0.2	-1.5	-0.5	-0.0	-1.0	-1.2
Average weekly beer plus cider intake	0.6	0.9	2.9	-1.7	-0.2	-0.5	-1.6	-0.1	-1.0	-0.9	0.4	0.6
Myopia	0.6	0.9	2.3	-0.4	-1.5	-0.9	-0.0	-1.4	-0.4	1.0	-1.1	-0.4
Reaction Time	0.5	0.9	5.5	-0.4	0.6	-0.1	-1.3	0.5	-0.5	-2.3	0.3	0.0
Age at First Birth	0.5	0.8	2.3	0.5	0.8	1.3	-0.9	0.1	0.5	1.5	1.0	0.0
Coronary Artery Disease (CAD)	0.5	0.6	3.1	0.0	0.0	0.0	0.0	0.0	0.0	0.8	-1.8	-1.4
Mean Putamen Volume	0.5	0.6	2.9	0.6	0.6	0.6	0.4	0.2	0.3	-1.7	-0.1	0.8
LDL Cholesterol	0.5	0.8	2.3	0.0	0.7	1.4	1.0	0.3	1.5	0.5	0.9	-0.2
Tanning	0.5	6.2	16.2	-0.3	-2.5	-2.7	4.0	-2.2	-1.2	-2.7	-3.4	-0.4
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.6	-0.9	-0.9	-0.5	-0.6	-0.5	-0.8	-1.6	-0.6	-0.2
Trunk fat percentage	0.5	1.8	7.8	1.6	0.3	-0.1	2.1	-0.7	0.8	2.8	-0.4	-0.4
Age when periods started (menarche)	0.5	1.2	2.5	1.2	1.6	1.4	-1.2	1.4	1.1	0.3	0.2	-0.0
Multivitamins +/- minerals	0.5	0.7	2.3	-1.1	-0.7	-1.5	-0.2	0.2	-1.3	-0.4	-0.4	0.3
Medication: Atenolol	0.5	0.6	3.4	0.4	0.1	-0.3	1.8	-1.0	0.4	1.0	-0.2	0.1
Medication: Levothyroxine sodium	0.5	0.9	2.6	-1.1	-0.7	-1.0	0.3	-1.1	-1.0	0.2	-1.6	-0.7
Past tobacco smoking	0.5	0.9	2.5	0.4	-0.6	0.6	1.6	-1.6	0.9	1.2	-0.5	0.2
Pulse rate	0.5	0.8	2.7	-1.4	-0.7	-0.1	-1.6	-0.8	-0.5	-0.6	-0.5	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.4	-0.5	-1.2	-0.1	1.0	-1.1	-0.0	-0.7	-0.4	-0.4
Mouth/teeth dental problems: Dentures	0.5	0.9	2.5	-0.8	-0.6	-1.2	0.1	-0.3	-1.2	-1.0	-1.6	-0.6
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	4.1	0.3	-0.2	-0.1	2.0	-1.1	0.7	0.5	-0.1	0.4
Glaucoma (self-reported)	0.5	0.6	3.7	0.0	-0.2	-0.8	0.0	-0.8	-0.5	1.9	-0.6	0.1
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.0	0.6	0.3	0.6	-0.2	0.6	1.0	-1.4	-0.9	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	2.8	0.1	0.4	-0.4	-0.6	0.9	-0.3	-1.7	-0.2	0.4
Mouth/teeth dental problems: Loose teeth	0.5	0.5	1.8	-0.4	-0.3	-0.4	1.1	-0.8	0.1	0.9	-1.3	0.1
Number of full sisters	0.5	0.6	3.4	0.5	-0.1	-0.0	1.9	-0.4	0.4	0.9	-0.5	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.5	2.0	0.1	0.0	-0.1	1.4	0.2	0.3	1.0	-1.1	-0.5
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.9	0.8	0.1	0.6	1.0	-0.0	0.6	1.4	0.8	0.7
Friendships satisfaction	0.5	0.6	1.1	1.0	0.4	0.3	0.6	0.3	1.0	-0.7	-0.8	1.1
Ever smoked	0.5	0.9	2.2	-1.0	0.5	-1.0	-1.3	1.0	-1.5	-0.6	0.6	-0.4
Ever depressed for a whole week	0.5	0.6	1.6	0.7	1.0	0.3	-1.2	1.1	0.5	-0.1	0.7	0.7
Worry (Nagel 2018)	0.4	0.9	2.8	1.7	1.3	0.7	-0.2	1.0	0.8	-0.1	0.6	0.9
Alzheimer’s Disease (including proxy)	0.4	0.5	2.6	-0.2	0.2	0.8	-0.1	-0.1	0.4	0.9	1.6	0.5
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.2	1.4	0.3	1.4	0.4	-0.3	1.5	1.5	0.3	-0.4
Crohns Disease (2012)	0.4	0.6	3.1	0.0	0.6	0.4	-1.0	0.6	0.2	-1.8	0.4	0.4
Systolic Blood Pressure	0.4	2.1	10.3	0.8	-0.4	0.1	3.2	-0.9	1.5	0.1	-1.8	1.2
Hearing difficulty/problems: Yes	0.4	0.5	1.6	-1.3	0.1	-0.7	-0.6	-0.1	-0.8	1.2	-0.5	-0.3
Relative age of first facial hair	0.4	0.9	2.6	-1.1	0.0	-1.5	-1.1	0.2	-1.6	0.7	0.5	0.1
Medication for hormone replacement therapy	0.4	0.4	1.2	-1.1	-0.7	-0.5	0.0	-0.6	-0.7	0.9	0.2	-0.1
Severe depression (siblings)	0.4	0.4	2.1	0.2	-0.5	-0.2	0.9	-0.1	0.1	1.4	-0.3	0.5
Had other major operations	0.4	0.5	1.9	-0.1	0.3	0.4	-0.8	0.8	0.0	1.4	1.0	-0.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.5	0.2	0.8	-0.0	-1.2	0.9	-0.3	0.9	0.0	-0.3
Fluid intelligence score	0.4	0.8	2.5	1.0	0.3	1.6	0.2	-0.0	1.5	0.7	0.8	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	5.9	0.1	-0.0	-0.5	0.5	-0.2	-0.3	2.4	-0.1	0.1
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.1	-1.4	-0.9	0.1	-0.7	-1.2	-0.2	-1.2	0.6	-0.7
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.0	-1.1	-0.2	-0.2	-0.3	-0.1	-0.6	0.7	0.1	-1.4
Qualifications: College or University degree	0.4	1.4	3.4	-1.1	-1.8	-0.9	-0.7	-1.8	-1.0	-1.3	-0.1	-1.0
Angina (self-reported)	0.4	0.5	1.9	0.5	0.4	0.5	-1.4	0.5	0.1	1.0	1.0	0.1
Medication: Seretide 50 evohaler	0.4	0.5	1.4	0.2	-0.2	-0.9	0.4	0.6	-0.4	-0.2	-1.2	1.1
Alcohol intake frequency.	0.4	1.0	3.6	0.1	-1.1	-0.5	1.2	-0.9	0.0	0.8	-1.9	-0.9
Smoking status: Previous	0.4	0.6	1.2	-0.7	-0.2	-0.9	-1.1	0.7	-1.1	-1.0	0.1	-0.6
Average weekly red wine intake	0.4	0.6	2.8	-0.8	0.5	0.8	-1.0	0.2	-0.1	-0.4	1.7	-0.1
Mineral and other dietary supplements	0.4	0.5	2.4	0.4	0.6	0.9	-0.3	-0.2	0.5	-0.2	1.6	0.7
Osteoarthritis (self-reported)	0.4	0.5	1.2	0.2	-0.2	1.1	-1.0	-0.6	0.7	1.0	0.8	0.4
Ever taken oral contraceptive pill	0.4	0.4	1.0	-0.6	-0.3	-0.7	-0.4	-0.7	-0.9	-1.0	-0.7	-0.4
Eye problems/disorders: Glaucoma	0.4	0.5	1.6	0.1	-0.3	-1.0	0.2	-0.8	-0.7	1.2	-0.8	0.1
Medication: Atorvastatin	0.4	0.5	1.8	-0.4	-0.7	-0.1	0.4	-0.9	-0.1	1.4	-0.6	-0.9
Prostate Cancer	0.3	0.4	1.3	0.0	-0.1	0.2	-0.8	0.3	0.3	-1.0	0.3	1.2
Body Mass Index (BMI) (2010)	0.3	0.4	0.8	0.0	0.0	-0.9	-0.9	0.5	-0.9	-0.8	0.4	-0.2
HbA1C	0.3	0.3	0.8	-0.2	-0.8	-0.5	0.2	-0.9	-0.0	0.5	-0.3	-0.7
Blood Platelet Count	0.3	3.2	6.1	-1.8	-0.8	-2.0	1.6	-2.0	-1.4	2.2	-0.9	2.5
Chronotype (morning person)	0.3	0.7	2.6	-0.1	-0.1	-0.9	1.6	-0.5	-0.2	0.0	-1.5	-0.2
Systolic blood pressure, automated reading	0.3	0.7	2.5	0.1	-0.3	-0.1	1.6	-1.1	0.7	0.2	-1.5	0.1
Angina	0.3	0.4	2.0	0.3	0.1	0.4	-1.4	0.2	-0.0	1.0	0.8	-0.2
Fed-up feelings	0.3	0.6	3.0	0.9	-0.0	0.0	0.7	0.5	0.4	1.7	-0.9	0.3
Nervous feelings	0.3	0.5	1.1	0.5	0.9	0.6	-1.1	0.1	0.3	0.8	1.0	0.7
Medication: Simvastatin	0.3	0.4	1.4	-0.1	-1.2	-0.5	0.6	-0.2	-0.1	-0.7	-1.0	-0.1
Hip circumference	0.3	1.4	5.5	-0.3	0.1	0.2	-2.3	0.7	-0.4	2.1	0.3	-1.3
Alcohol intake versus 10 years previously	0.3	0.4	0.8	-0.9	-0.8	-0.7	0.7	-0.8	-0.4	0.8	-0.2	-0.4
Falls in the last year	0.3	0.5	1.3	0.3	0.4	0.3	0.9	-0.7	0.9	-0.2	-0.6	1.2
Happiness	0.3	0.4	1.3	-0.5	0.3	0.1	-0.5	-0.5	-0.1	1.0	0.6	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.0	-0.7	-0.0	-0.2	-1.0	-0.0	-0.8	0.7	-0.2	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.9	0.4	0.8	0.3	-0.3	0.8	0.3	-0.8	0.2	0.9
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	2.1	-0.7	0.0	-0.5	-0.3	-0.9	-0.6	-0.1	-1.5	-0.4
Number of full brothers	0.3	0.4	2.1	-0.2	-0.1	-0.5	1.1	-0.1	-0.2	1.4	0.3	0.3
Pulse rate, automated reading	0.3	0.9	3.1	0.7	0.3	1.1	-0.2	1.3	1.3	0.1	-1.8	0.4
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.1	-0.8	0.1	-0.7	-0.4	-0.5	-1.1	-1.0	0.1	-0.1
Long-standing illness, disability or infirmity	0.3	0.4	1.7	-0.5	-0.3	-0.3	0.3	-0.1	-0.1	1.3	-1.2	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.1	0.0	0.3	0.7	0.0	-0.2	0.5	0.8	1.0	0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	2.0	-0.2	0.6	-0.1	0.3	-0.4	0.0	0.2	1.4	1.3
Illnesses of father: None of the above (group 1)	0.3	0.3	0.8	0.4	-0.4	0.1	-0.6	0.7	-0.4	0.8	0.9	-0.2
High cholesterol (Self-reported)	0.3	0.6	2.0	0.2	-0.4	-0.4	1.4	-0.0	0.4	-1.2	-1.2	0.3
Cholesterol lowering medication	0.3	0.4	1.6	-0.3	-0.6	0.1	0.8	-0.3	0.3	-1.0	-1.3	0.1
Alcohol drinker status: Previous	0.3	0.3	1.0	-0.6	0.4	-0.2	-0.7	1.0	-0.5	0.7	0.5	-0.1
Crohns Disease (2017)	0.2	0.5	1.4	0.4	0.4	0.5	-1.0	1.1	0.2	-1.2	-0.3	-0.6
Ovarian Cancer	0.2	0.2	1.5	0.3	-0.1	-0.0	0.1	0.3	0.1	-0.2	0.6	1.2
Lung FVC	0.2	1.2	3.3	-0.2	0.8	0.8	-1.5	1.2	0.4	1.2	1.8	0.8
Average weekly spirits intake	0.2	0.2	0.8	0.4	-0.2	0.3	-0.7	0.1	0.2	-0.2	0.4	0.9
Relative age voice broke	0.2	0.3	1.7	-0.0	0.6	-0.4	0.1	0.2	-0.2	1.3	0.4	0.4
Serious illness, injury or assault to yourself	0.2	0.2	0.7	-0.1	-0.5	-0.5	-0.3	0.3	-0.4	-0.1	-0.8	-0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.0	0.1	1.0	0.2	-0.5	0.6	-0.1	-0.2	-0.0	-0.1
Qualifications: None of the above	0.2	0.4	1.5	-0.0	1.2	0.8	-0.4	0.9	0.6	0.2	0.0	-0.1
Noisy workplace	0.2	0.3	1.9	-0.3	-0.0	-0.1	0.5	0.1	-0.0	1.4	-0.1	-0.4
Lung cancer (father)	0.2	0.2	0.7	-0.0	-0.4	-0.0	-0.6	0.6	0.1	0.8	0.2	-0.3
Suffer from ‘nerves’	0.2	0.4	0.8	-0.0	-0.2	-0.6	-0.7	0.2	-0.8	-0.7	-0.7	-0.9
Family relationship satisfaction	0.2	0.3	0.8	-0.1	0.9	0.3	0.3	-0.0	0.4	-0.8	-0.6	0.5
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.7	0.6	0.4	0.5	0.1	0.8	0.7	0.3	-0.3	0.4
Fractured/broken bones in last 5 years	0.2	0.2	0.7	0.1	0.4	0.3	-0.6	0.7	0.1	-0.4	0.8	0.0
Commuting to job workplace: Cycle	0.2	0.3	1.0	-0.4	-0.3	0.0	0.8	-0.5	0.0	-1.0	-0.0	-0.3
Bipolar Disorder or Schizophrenia	0.1	0.3	1.6	0.0	-0.0	-0.2	1.3	-0.6	0.4	-0.2	-0.1	0.5
Bipolar Disorder (2011)	0.1	0.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.8	0.3
Hypothyroidism (self reported)	0.1	0.3	1.0	-0.4	0.6	0.1	-0.7	-0.1	-0.1	-0.6	-1.0	0.6
Hair Pigment	0.1	1.9	12.7	1.0	0.1	0.6	-0.2	1.0	0.4	3.6	-0.5	1.2
Townsend deprivation index at recruitment	0.1	0.2	0.5	-0.1	0.3	0.7	0.4	0.2	0.7	0.4	0.1	-0.0
Mouth/teeth dental problems	0.1	0.2	0.5	0.6	0.2	0.3	0.5	-0.3	0.6	-0.4	0.0	0.7
Medication: Cholesterol lowering	0.1	0.2	0.6	0.6	-0.8	-0.4	0.6	-0.2	0.1	-0.1	-0.3	-0.2
Arm fat mass (right)	0.1	0.4	2.7	0.3	0.1	-0.5	-0.4	-0.2	-0.3	1.6	-0.6	-0.5
Tense / ‘highly strung’	0.1	0.2	0.8	-0.8	0.0	0.0	-0.9	-0.5	-0.4	0.2	0.3	-0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.6	-0.5	0.3	-0.2	-0.7	-0.1	-0.4	0.1	-0.2	-0.5
Arm fat mass (left)	0.1	0.5	3.4	0.5	0.1	-0.2	-0.3	-0.1	-0.1	1.8	-0.4	-0.4
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.5	-0.7	-0.5	-0.1	-0.2	-0.4	-0.4	0.4	0.3	0.3
Ever had prostate specific antigen (PSA) test	0.1	0.2	0.8	-0.1	0.3	-0.1	-0.9	-0.7	-0.3	0.1	0.0	0.1

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