Best TWAS P=1.49e-11 · Best GWAS P=2.32e-21 conditioned to 5.74e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | LRRC1 | 0.09 | 0.07 | lasso | 2 | 0.06 | 1.8e-05 | 6.7 | -6.8 | 1.5e-11 | 0.37 | 0.92 | 0.02 | TRUE |
| 2 | GTEx | Adipose Subcutaneous | RP3-523E19.2 | 0.08 | 0.07 | enet | 12 | 0.06 | 2.6e-05 | 6.7 | -6.3 | 3.3e-10 | 0.35 | 0.91 | 0.01 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | LRRC1 | 0.20 | 0.01 | enet | 14 | 0.15 | 2.3e-05 | -1.6 | 5.3 | 9.2e-08 | -0.22 | 0.03 | 0.05 | FALSE |