[Hub]/) : Traits : Heel T-Score : ← →

chr6:42,611,872-46,745,999

Best TWAS P=2.31e-85 · Best GWAS P=4.58e-129 conditioned to 0

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	SUPT3H	0.33	0.26	enet	43	0.44	2.5e-59	-4.21	-11.9	8.7e-33	0.23	1.00	0.00	FALSE
2	GTEx	Adipose Visceral Omentum	SUPT3H	0.27	0.10	lasso	7	0.06	3.4e-04	14.95	-18.2	4.1e-74	0.42	0.96	0.02	FALSE
3	GTEx	Artery Tibial	SUPT3H	0.13	0.01	enet	21	0.02	1.9e-02	-14.71	-17.8	6.4e-71	0.62	0.02	0.96	TRUE
4	GTEx	Brain Caudate basal ganglia	SUPT3H	0.22	0.12	lasso	6	0.10	8.1e-04	-3.89	-5.6	2.2e-08	-0.10	0.30	0.05	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	SUPT3H	0.20	0.08	lasso	6	0.10	3.0e-04	15.57	-11.7	1.7e-31	0.09	0.42	0.03	TRUE
6	GTEx	Cells Transformed fibroblasts	SUPT3H	0.15	0.10	lasso	4	0.13	8.8e-10	15.66	-13.1	2.1e-39	0.05	1.00	0.00	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	SUPT3H	0.27	0.01	lasso	3	0.00	2.7e-01	-15.51	-16.4	2.1e-60	0.40	0.10	0.25	TRUE
8	GTEx	Esophagus Mucosa	SUPT3H	0.08	0.09	lasso	3	0.08	6.4e-06	14.95	-16.4	1.2e-60	0.28	0.84	0.05	FALSE
9	GTEx	Esophagus Muscularis	SUPT3H	0.10	0.03	enet	20	0.02	1.3e-02	-15.51	-13.7	5.3e-43	0.38	0.13	0.45	FALSE
10	GTEx	Lung	SUPT3H	0.10	0.06	enet	21	0.03	1.3e-03	15.21	-16.6	3.7e-62	0.25	0.84	0.02	FALSE
11	GTEx	Nerve Tibial	SUPT3H	0.17	0.12	lasso	5	0.10	2.2e-07	15.21	-15.3	1.0e-52	0.20	1.00	0.00	FALSE
12	GTEx	Pancreas	AARS2	0.24	0.04	enet	12	0.05	3.8e-03	0.45	5.2	1.8e-07	-0.11	0.08	0.24	TRUE
13	GTEx	Pancreas	SUPT3H	0.11	0.07	lasso	2	0.05	3.6e-03	15.29	-15.3	9.0e-53	0.20	0.36	0.05	FALSE
14	GTEx	Skin Sun Exposed Lower leg	SUPT3H	0.07	0.03	lasso	5	0.04	4.2e-04	15.21	-17.3	4.1e-67	0.36	0.47	0.07	FALSE
15	GTEx	Spleen	SUPT3H	0.32	0.06	enet	12	0.11	9.5e-04	14.25	-16.4	2.1e-60	0.23	0.26	0.29	FALSE
16	GTEx	Testis	CLIC5	0.40	0.17	lasso	7	0.20	2.0e-09	-5.59	-5.6	2.4e-08	-0.09	1.00	0.00	TRUE
17	GTEx	Testis	SUPT3H	0.30	0.16	lasso	7	0.17	6.7e-08	-4.83	-7.0	3.0e-12	-0.08	0.99	0.00	FALSE
18	GTEx	Thyroid	SUPT3H	0.29	0.07	lasso	8	0.07	7.3e-06	-15.93	-14.8	7.0e-50	0.65	0.89	0.05	FALSE
19	METSIM	Adipose	SUPT3H	0.11	0.04	bslmm	657	0.06	2.7e-09	15.66	-13.8	2.0e-43	0.31	1.00	0.00	TRUE
20	NTR	Blood	SUPT3H	0.03	0.02	lasso	7	0.02	1.9e-07	-5.32	-8.6	1.1e-17	-0.06	1.00	0.00	TRUE
21	NTR	Blood	ZNF318	0.04	0.03	lasso	8	0.02	1.3e-08	5.97	6.3	3.3e-10	0.05	0.99	0.01	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	SUPT3H	0.15	0.13	blup	643	0.17	3.4e-21	-4.91	-10.2	3.1e-24	0.08	1.00	0.00	FALSE
23	YFS	Blood	SUPT3H	0.06	0.09	lasso	13	0.12	2.2e-36	15.21	-11.7	1.8e-31	0.02	1.00	0.00	FALSE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	SUPT3H	0.02	0.01	blup	191	0.01	3.0e-03	14.95	-15.1	2.5e-51	0.18	0.86	0.00	FALSE
25	The Cancer Genome Atlas	Colon Adenocarcinoma	SUPT3H	0.08	0.01	blup	191	0.05	1.0e-03	15.66	-18.0	4.1e-72	0.38	0.28	0.08	FALSE
26	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SUPT3H	0.04	0.01	blup	191	0.02	6.5e-03	-4.15	-13.0	2.2e-38	0.15	0.67	0.01	TRUE
27	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CRIP3	0.08	0.08	blup	34	0.07	1.0e-04	6.34	6.4	1.4e-10	0.04	0.00	0.99	TRUE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	SUPT3H	0.07	0.05	enet	12	0.08	1.1e-09	-4.83	-12.2	2.2e-34	0.03	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	SUPT3H	0.03	0.03	lasso	2	0.02	8.9e-04	15.50	-14.9	2.7e-50	0.18	0.31	0.06	FALSE
30	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SUPT3H	0.12	0.08	blup	191	0.09	2.8e-04	15.08	-17.7	4.2e-70	0.30	0.66	0.04	FALSE
31	The Cancer Genome Atlas	Soft Tissue Sarcoma	ZNF318	0.04	0.02	blup	48	0.04	2.2e-03	6.35	6.2	6.3e-10	0.06	0.01	0.80	FALSE
32	The Cancer Genome Atlas	Stomach Adenocarcinoma	SUPT3H	0.05	0.01	blup	191	0.00	1.4e-01	-3.89	-11.0	6.5e-28	0.02	0.13	0.05	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	SUPT3H	0.06	0.04	lasso	4	0.05	2.1e-05	15.59	-19.6	2.3e-85	0.50	0.60	0.20	TRUE