[Hub]/) : Traits : Heel T-Score : ← →

chr7:37,189,875-39,364,993

Best TWAS P=2.4e-104 · Best GWAS P=5.11e-221 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	EPDR1	0.12	0.06	lasso	5	0.05	9.4e-05	13.738	7.1	1.5e-12	-0.05	0.94	0.00	TRUE
2	GTEx	Adipose Visceral Omentum	EPDR1	0.18	0.01	lasso	4	0.01	8.9e-02	13.738	12.0	2.4e-33	0.02	0.17	0.10	FALSE
3	GTEx	Artery Aorta	SFRP4	0.32	0.27	lasso	6	0.24	2.0e-13	8.005	-8.4	4.3e-17	0.04	1.00	0.00	FALSE
4	GTEx	Artery Tibial	EPDR1	0.27	0.15	lasso	12	0.16	3.4e-12	13.738	11.1	7.7e-29	0.09	1.00	0.00	TRUE
5	GTEx	Brain Hippocampus	AMPH	0.40	0.01	enet	32	-0.01	4.5e-01	-0.326	8.9	7.7e-19	0.17	0.14	0.05	TRUE
6	GTEx	Lung	EPDR1	0.15	0.06	enet	24	0.08	9.8e-07	4.331	9.4	4.5e-21	0.08	0.71	0.01	FALSE
7	GTEx	Nerve Tibial	EPDR1	0.29	0.14	lasso	4	0.23	2.7e-16	16.276	14.3	2.8e-46	0.10	1.00	0.00	FALSE
8	GTEx	Pancreas	EPDR1	0.18	0.15	lasso	5	0.17	1.0e-07	-19.705	18.9	1.4e-79	0.27	0.69	0.02	TRUE
9	GTEx	Thyroid	EPDR1	0.19	0.06	enet	25	0.10	4.0e-08	13.738	17.6	3.0e-69	0.24	0.65	0.23	FALSE
10	METSIM	Adipose	RP11-121A8.1	0.06	0.09	lasso	3	0.08	3.6e-12	5.552	-5.6	2.6e-08	-0.08	1.00	0.00	TRUE
11	NTR	Blood	TXNDC3	0.03	0.00	bslmm	614	0.01	9.3e-05	1.203	7.0	3.4e-12	0.26	0.10	0.08	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	EPDR1	0.17	0.06	lasso	6	0.10	2.5e-13	9.595	13.4	4.8e-41	0.10	1.00	0.00	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	EPDR1	0.06	0.01	enet	22	0.06	6.7e-12	6.288	8.3	6.7e-17	-0.05	0.95	0.00	FALSE
14	The Cancer Genome Atlas	Esophageal Carcinoma	TXNDC3	0.48	-0.01	blup	129	0.11	1.9e-04	12.620	-8.5	2.4e-17	-0.11	0.01	0.37	TRUE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EPDR1	0.08	0.04	enet	3	0.05	5.4e-06	13.738	21.7	2.4e-104	0.34	0.33	0.62	TRUE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TXNDC3	0.07	0.02	blup	129	0.03	5.1e-04	-1.809	-5.8	9.0e-09	0.04	0.06	0.20	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	EPDR1	0.05	0.02	blup	113	0.01	1.1e-02	9.595	6.8	9.4e-12	0.05	0.04	0.05	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	TXNDC3	0.07	0.00	blup	129	0.01	1.1e-02	1.998	5.6	1.7e-08	0.04	0.04	0.08	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	TXNDC3	0.04	0.00	blup	129	0.02	2.4e-03	0.085	-6.5	7.8e-11	-0.04	0.07	0.04	TRUE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	EPDR1	0.17	0.10	enet	15	0.13	8.0e-14	-4.594	-6.5	7.6e-11	-0.01	1.00	0.00	TRUE
21	The Cancer Genome Atlas	Testicular Germ Cell Tumors	EPDR1	0.09	0.10	lasso	2	0.06	2.8e-03	-10.428	10.9	1.1e-27	0.06	0.09	0.05	TRUE