TWAS hub - AMPH

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1060	0.0290	5.6e-05	0.077	0.034	0.066	0.066	0.070	1.2e-09	5.3e-05	1.8e-08	1.9e-08	7.1e-09
2	GTEx	Adipose Subcutaneous	0.4810	0.0440	0.0e+00	0.500	NA	0.510	NA	0.516	1.7e-46	NA	7.0e-48	NA	1.4e-48
3	GTEx	Adipose Visceral Omentum	0.3010	0.0640	5.7e-06	0.235	NA	0.268	NA	0.279	1.8e-12	NA	3.2e-14	NA	7.4e-15
4	GTEx	Artery Tibial	0.1329	0.0434	1.0e-03	0.091	NA	0.045	NA	0.073	1.3e-07	NA	2.0e-04	NA	2.3e-06
5	GTEx	Brain Hippocampus	0.4000	0.1097	9.1e-04	0.007	NA	-0.005	NA	-0.012	2.1e-01	NA	4.5e-01	NA	8.1e-01
6	GTEx	Breast Mammary Tissue	0.3310	0.0680	3.8e-06	0.189	NA	0.186	NA	0.185	5.2e-10	NA	7.5e-10	NA	8.1e-10
7	GTEx	Breast Mammary Tissue (Male)	0.1440	0.1109	1.4e-01	0.091	NA	-0.011	NA	0.005	4.0e-03	NA	6.9e-01	NA	2.4e-01
8	GTEx	Breast Mammary Tissue (Female)	0.4373	0.0997	5.4e-04	0.258	NA	0.219	NA	0.247	2.7e-08	NA	3.8e-07	NA	5.5e-08
9	GTEx	Cells Transformed fibroblasts	0.1850	0.0530	1.3e-04	0.089	NA	0.055	NA	0.083	3.3e-07	NA	5.6e-05	NA	9.0e-07
10	GTEx	Esophagus Gastroesophageal Junction	0.2450	0.0800	3.9e-03	0.188	NA	0.157	NA	0.150	2.3e-07	NA	2.6e-06	NA	4.5e-06
11	GTEx	Muscle Skeletal	0.2207	0.0392	6.8e-11	0.224	NA	0.215	NA	0.223	1.1e-21	NA	7.4e-21	NA	1.3e-21
12	GTEx	Nerve Tibial	0.4445	0.0491	0.0e+00	0.465	NA	0.452	NA	0.475	2.2e-36	NA	3.7e-35	NA	1.6e-37
13	GTEx	Skin Not Sun Exposed Suprapubic	0.3240	0.0750	2.4e-05	0.247	NA	0.242	NA	0.232	8.6e-14	NA	1.7e-13	NA	6.4e-13
14	GTEx	Skin Sun Exposed Lower leg	0.3850	0.0480	0.0e+00	0.378	NA	0.321	NA	0.356	7.2e-33	NA	3.9e-27	NA	1.1e-30
15	GTEx	Testis	0.2900	0.0860	1.0e-03	0.088	NA	0.085	NA	0.086	9.8e-05	NA	1.4e-04	NA	1.2e-04
16	GTEx	Thyroid	0.1700	0.0480	2.3e-04	0.161	NA	0.179	NA	0.183	2.4e-12	NA	1.1e-13	NA	5.5e-14
17	METSIM	Adipose	0.1966	0.0321	0.0e+00	0.213	0.140	0.198	0.204	0.212	3.2e-31	2.5e-20	6.9e-29	7.0e-30	4.5e-31
18	ROSMAP	Brain Pre-frontal Cortex	0.0516	0.0223	1.3e-02	0.012	0.007	0.031	0.013	0.024	8.3e-03	3.8e-02	7.1e-05	6.3e-03	4.0e-04
19	TCGA	Prostate Adenocarcinoma	0.0657	0.0267	3.8e-03	-0.002	0.031	0.015	NA	0.002	5.3e-01	3.3e-04	8.8e-03	NA	1.9e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Medication: Lansoprazole	4.0	4.5	8.1	2.0	2.4	2.8	2.3	-0.1	2.3	2.8	2.1	-1.8	2.8	2.4	2.3	2.1	2.3	0.9	2.6	2.2	0.7	-0.6
Chronic bronchitis/emphysema (mother)	3.9	4.6	8.6	1.9	2.3	2.6	2.2	0.1	2.9	2.3	2.2	-1.7	2.4	2.5	2.3	2.8	2.3	1.1	2.5	2.4	1.2	-0.3
Respiratory disease	3.8	8.5	14.4	3.0	3.3	3.4	3.1	-1.3	3.6	3.0	3.8	0.2	3.4	3.4	3.3	3.2	3.2	1.0	3.4	3.4	1.8	0.8
Frequency of depressed mood in last 2 weeks	3.8	5.4	12.6	2.6	2.6	2.5	2.3	1.4	3.5	2.4	3.2	-0.9	2.5	2.7	2.5	2.4	2.3	-0.7	2.7	2.7	0.4	-0.3
Osteoarthritis (self-reported)	3.6	4.7	7.0	-1.5	-2.6	-2.5	-2.5	1.5	-1.9	-2.1	-2.6	-1.3	-2.2	-2.5	-2.6	-2.4	-2.5	-1.1	-2.5	-2.6	-1.1	-1.6
Neuroticism (2016)	3.3	4.8	9.2	-2.3	-2.6	-2.3	-2.4	3.0	-1.3	-1.6	-2.2	-1.0	-2.4	-2.5	-2.6	-2.7	-2.6	-0.2	-2.4	-2.6	-0.3	-2.0
Ever used hormone-replacement therapy (HRT)	3.1	3.9	6.7	-1.7	-2.5	-2.3	-2.5	1.1	-1.1	-2.6	-1.7	-2.0	-1.8	-2.3	-2.4	-1.9	-2.5	0.9	-2.5	-2.2	-1.0	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	3.0	3.6	5.7	-1.9	-2.2	-2.3	-2.3	0.3	-1.4	-2.2	-1.9	-1.2	-0.9	-2.1	-2.2	-2.3	-2.4	-1.0	-2.2	-2.2	-2.0	0.3
Coronary Artery Disease (CAD)	2.8	3.3	6.5	-1.6	-2.1	-1.7	-2.1	-1.6	-2.0	-1.3	-2.4	1.3	-2.5	-2.2	-2.1	-2.5	-2.0	-0.6	-1.8	-1.9	0.2	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	2.7	3.5	7.9	2.8	2.0	2.1	1.6	0.6	2.7	1.4	2.4	-0.8	2.3	2.1	1.8	2.0	1.7	0.4	1.8	2.0	1.5	-1.3
Asthma (self-reported)	2.7	5.4	9.3	2.5	2.7	2.6	2.6	-0.5	2.7	1.9	3.0	-0.1	2.4	2.8	2.7	3.0	2.7	0.4	2.5	2.8	1.9	0.6
Eye problems/disorders: Glaucoma	2.7	3.2	5.5	-1.9	-2.1	-2.2	-2.1	-0.4	-2.1	-1.6	-1.9	-0.3	-1.8	-1.9	-2.1	-1.9	-2.4	-0.3	-1.9	-2.1	-2.0	-0.2
Fractured/broken bones in last 5 years	2.7	3.5	7.3	2.4	2.1	2.0	1.9	-0.4	2.7	0.7	2.4	-1.2	1.3	2.1	2.1	2.4	2.1	0.4	1.7	2.4	2.1	0.3
Asthma	2.4	4.7	8.1	2.4	2.6	2.3	2.5	-0.2	2.5	1.5	2.8	-0.1	2.2	2.6	2.6	2.8	2.6	0.4	2.2	2.6	1.8	0.6
Osteoporosis (self-reported)	2.4	3.0	11.3	2.2	1.8	1.3	1.9	-3.4	0.8	-0.1	1.1	1.5	1.8	1.9	2.0	2.1	1.9	-0.4	1.1	1.7	1.6	1.5
Alcohol drinker status: Never	2.4	2.9	5.6	-1.5	-1.9	-2.3	-2.0	0.4	-1.6	-1.5	-1.6	0.7	-2.4	-2.0	-2.0	-2.2	-1.9	-0.5	-1.8	-1.8	-0.2	-1.8
Risk taking	2.4	3.6	6.5	-1.7	-2.0	-1.3	-1.9	-1.8	-1.7	-0.5	-2.5	0.6	-2.2	-2.0	-2.0	-2.3	-1.9	-2.5	-1.5	-2.2	-1.1	2.4
Worry too long after embarrassment	2.2	3.7	7.1	-2.3	-2.5	-2.1	-2.6	0.6	-1.5	-0.8	-1.8	-0.7	-2.1	-2.4	-2.6	-2.4	-2.4	-0.4	-1.9	-2.7	-0.5	0.1
Diabetes (father)	2.1	2.6	4.7	-1.8	-2.0	-2.0	-1.9	0.3	-1.5	-0.9	-2.0	-0.6	-1.9	-2.2	-2.0	-1.9	-2.0	-0.4	-1.7	-2.1	-0.0	0.8
Supplements: Fish oil (including cod liver oil)	2.1	2.7	4.4	-1.3	-2.0	-1.8	-1.9	0.0	-1.4	-2.1	-1.8	-1.1	-1.3	-2.0	-2.0	-1.5	-1.7	-1.6	-2.1	-1.9	-0.2	-1.6
Depressed Affect (Nagel 2018)	2.0	4.2	10.8	-1.6	-2.2	-2.2	-2.3	2.1	-0.1	-1.8	-1.0	-3.3	-1.8	-1.9	-2.2	-2.1	-2.5	-1.8	-2.0	-2.0	-2.4	-2.0
Average weekly fortified wine intake	2.0	2.4	4.8	1.9	1.9	1.9	1.9	0.2	1.8	0.6	1.8	0.4	0.6	1.9	2.0	2.0	1.8	0.4	1.6	2.2	0.0	1.3
Handedness (chirality/laterality): Left-handed	1.9	2.2	4.1	-1.5	-1.7	-1.8	-1.8	0.2	-1.6	-1.4	-2.0	-0.3	-0.7	-1.8	-1.7	-1.4	-1.8	-1.9	-1.7	-1.6	0.2	-1.1
Neuroticism	1.8	4.4	17.0	-1.8	-2.4	-2.0	-2.3	2.6	-0.1	-1.3	-1.1	-4.1	-0.9	-2.0	-2.4	-2.1	-2.4	-0.6	-2.0	-2.3	-2.6	-1.7
Mother’s age at death	1.8	2.3	3.5	1.5	1.7	1.8	1.4	0.7	1.7	1.7	1.6	0.0	1.6	1.7	1.6	1.6	1.4	1.9	1.8	1.8	1.4	-0.2
Fed-up feelings	1.7	3.0	12.2	-1.5	-1.6	-1.8	-1.7	2.6	0.0	-0.9	-0.6	-3.5	-0.8	-1.4	-1.7	-1.8	-1.7	-1.2	-1.4	-1.6	-1.9	-2.1
Ever had hysterectomy (womb removed)	1.6	1.8	6.1	-0.7	-1.6	-1.2	-1.4	2.5	-0.7	-1.3	-0.8	-1.1	-0.8	-1.6	-1.5	-1.1	-1.6	-1.2	-1.5	-1.5	-1.2	0.2
Townsend deprivation index at recruitment	1.6	2.2	4.8	1.5	1.7	1.3	1.8	-2.2	1.2	1.3	1.1	0.1	0.3	1.6	1.7	1.5	2.1	1.2	1.5	1.4	2.0	0.3
Depression (Nagel 2018)	1.5	2.3	7.8	1.4	1.2	1.3	1.1	2.8	2.5	2.0	1.7	-1.2	1.7	1.3	1.1	1.2	1.1	-0.2	1.6	1.2	-0.2	-1.5
Body Mass Index (BMI) (2010)	1.5	2.0	5.0	0.9	1.6	2.2	1.5	-0.8	1.2	1.9	1.3	-0.0	1.7	1.6	1.5	1.1	1.5	-0.6	1.7	1.5	1.9	-0.7
Average weekly spirits intake	1.5	1.8	5.0	-1.6	-1.5	-1.3	-1.9	-0.0	-0.6	-0.9	-1.1	-2.2	-1.1	-1.4	-1.6	-1.9	-1.9	0.6	-1.2	-1.3	-0.3	-0.8
Glaucoma (self-reported)	1.5	1.8	3.4	-1.1	-1.5	-1.5	-1.5	-0.7	-1.4	-1.4	-1.4	-0.4	-1.6	-1.3	-1.4	-1.7	-1.7	-0.4	-1.5	-1.5	-1.8	0.3
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.3	16.2	-1.9	-1.6	-1.8	-1.7	4.0	-1.2	-1.2	-0.7	-1.1	-1.5	-1.5	-1.6	-1.1	-1.7	-0.6	-1.4	-1.6	-3.6	0.1
Multivitamins +/- minerals	1.4	1.8	11.3	-1.1	-1.1	-1.1	-1.0	-0.8	-1.7	-1.1	-1.9	0.8	-0.1	-1.3	-1.1	-1.0	-1.0	-3.4	-1.2	-1.4	-0.2	1.1
Medication: Seretide 50 evohaler	1.4	1.6	5.4	-0.9	-1.3	-1.7	-1.0	-0.4	-1.0	-1.2	-1.3	0.3	-1.4	-1.3	-1.1	-1.0	-1.2	-1.5	-1.4	-1.4	-2.3	0.5
Smoking status: Previous	1.4	2.2	7.6	-1.6	-1.6	-1.3	-1.7	1.5	-0.4	-0.2	-1.3	-1.3	-1.6	-1.5	-1.7	-1.6	-1.8	-0.1	-1.1	-1.6	-2.8	-0.2
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	3.9	-1.3	-1.6	-1.9	-1.6	-0.2	-1.7	-2.0	-1.9	-0.9	-1.2	-1.6	-1.6	-1.6	-1.5	0.2	-1.9	-1.7	-0.4	-0.9
Number of self-reported non-cancer illnesses	1.4	2.4	4.8	2.2	1.8	1.9	1.9	-0.1	2.1	0.6	1.8	-0.3	1.3	1.9	1.9	1.8	1.9	0.3	1.4	1.7	0.7	0.1
Heart disease (siblings)	1.4	1.7	3.1	1.1	1.5	1.2	1.4	-1.3	0.8	1.3	1.2	0.9	0.8	1.6	1.5	1.3	1.3	0.3	1.6	1.7	1.2	-1.8
Stomach or abdominal pain in last month	1.3	1.7	4.7	1.4	1.3	1.6	1.4	-0.0	1.9	1.1	1.2	-2.2	1.6	1.4	1.3	1.3	1.3	0.1	1.3	1.1	0.2	0.0
Neuroticism score	1.3	2.7	8.4	-1.2	-1.8	-1.5	-1.8	2.5	0.2	-0.6	-0.6	-2.9	-1.1	-1.4	-1.8	-1.7	-1.8	-1.1	-1.3	-1.8	-2.2	-1.8
Mineral and other dietary supplements	1.3	1.8	4.4	1.0	1.5	1.3	1.5	-0.2	1.5	1.4	1.4	0.1	0.4	1.6	1.5	1.0	1.4	1.6	1.6	1.5	-0.4	2.1
Miserableness	1.3	2.2	4.1	-1.5	-1.7	-1.5	-1.8	2.0	-0.1	-0.5	-0.9	-1.8	-1.5	-1.5	-1.7	-1.8	-2.0	-1.3	-1.2	-1.6	-1.1	-1.0
Financial situation satisfaction	1.3	1.6	4.1	1.9	1.3	1.1	1.6	0.2	1.5	0.7	1.1	-1.0	2.0	1.2	1.4	1.4	1.5	-0.9	1.1	1.1	0.7	-0.2
Crohns Disease (2017)	1.2	2.6	5.6	1.8	1.8	1.8	1.7	0.5	2.1	1.0	2.4	-1.6	1.5	1.9	1.8	1.5	1.6	0.7	1.7	2.1	0.1	-0.3
Waist Hip Ratio (WHR)	1.2	5.5	9.0	-2.9	-2.9	-2.8	-2.8	-0.0	-2.5	-1.9	-2.8	0.8	-2.5	-2.8	-2.9	-2.7	-2.9	-0.6	-2.6	-3.0	-0.0	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.7	4.8	1.2	1.0	1.3	1.0	1.9	2.2	2.0	1.4	-1.1	1.3	1.0	1.0	1.0	1.1	-0.1	1.5	0.9	0.5	-1.2
Impedance of arm (left)	1.2	5.7	9.6	2.2	2.7	2.3	3.1	1.8	1.9	2.0	2.5	1.2	2.4	2.6	2.8	3.1	3.1	1.9	2.4	2.5	2.2	1.1
Length of working week for main job	1.2	1.3	3.1	-1.3	-1.2	-0.5	-1.1	0.3	-1.4	-1.1	-1.4	0.5	-1.6	-1.2	-1.1	-1.0	-1.1	-1.8	-1.1	-1.2	0.6	-1.2
Hypothyroidism/myxoedema (self-reported)	1.2	2.4	4.2	1.9	1.8	2.0	1.6	-0.4	2.0	1.2	1.9	-0.5	1.6	1.8	1.8	1.8	1.6	-0.0	1.7	1.8	-0.6	0.9
Qualifications: nursing, teaching	1.2	1.9	3.9	2.0	1.6	1.2	1.4	0.0	1.0	0.0	1.3	1.8	1.6	1.6	1.6	1.7	1.5	-0.8	1.1	1.8	0.8	-0.5
Medication: Omeprazole (e.g. Zanprol)	1.2	1.5	3.6	-0.9	-1.3	-1.5	-1.2	0.6	-0.9	-1.9	-1.4	-1.3	-0.7	-1.3	-1.3	-1.3	-1.2	0.9	-1.6	-1.2	-0.8	-0.8
Vitamin and mineral supplements	1.1	1.4	7.2	1.0	1.2	1.0	1.1	0.7	1.3	0.8	1.6	-0.1	0.1	1.3	1.2	1.0	1.1	2.7	1.2	1.5	0.0	-1.1
Supplements: Glucosamine	1.1	1.5	2.9	-1.1	-1.3	-1.4	-1.5	0.8	-1.4	-1.7	-1.0	0.4	-1.0	-1.3	-1.4	-1.0	-1.5	-1.2	-1.5	-1.1	-0.7	-1.1
Chest pain or discomfort	1.1	1.6	3.0	1.2	1.2	0.8	1.2	-0.1	1.7	1.7	1.2	-1.7	1.3	1.2	1.1	1.3	1.1	1.4	1.4	1.1	-0.3	1.4
Family relationship satisfaction	1.1	1.4	3.2	1.3	1.3	1.2	1.3	-1.0	1.2	0.6	1.1	-0.1	1.8	1.3	1.4	1.2	1.2	0.2	1.1	1.4	1.1	1.2
Leg pain on walking	1.1	1.4	4.5	-1.0	-1.2	-1.4	-1.3	1.3	-0.5	-0.6	-1.1	-2.0	0.1	-1.2	-1.2	-1.1	-1.5	0.2	-1.0	-1.0	0.1	-2.1
Tinnitus: Yes, now most or all of the time	1.1	1.3	8.1	-1.2	-0.8	-1.2	-0.8	-0.9	-0.8	-0.9	-0.6	-0.2	-1.0	-0.7	-0.7	-0.8	-0.8	2.9	-0.8	-0.7	-1.2	1.9
HbA1C	1.0	1.1	4.9	1.4	0.9	1.1	1.1	-1.7	0.3	1.2	-0.1	1.1	0.6	0.8	0.9	0.7	0.8	-2.2	1.0	0.7	0.9	1.0
Relative age of first facial hair	1.0	2.1	3.8	-1.4	-1.5	-1.3	-1.6	-1.0	-1.5	-1.1	-1.4	-1.4	-1.9	-1.6	-1.6	-1.7	-1.6	-1.5	-1.4	-1.4	0.3	-1.3
Severe depression (siblings)	1.0	1.2	3.2	0.8	1.1	0.4	1.0	0.2	1.5	0.0	1.6	-1.8	1.8	1.1	1.1	1.0	0.8	0.2	0.8	1.3	0.8	0.7
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	21.5	-1.2	-1.0	-0.9	-1.0	4.6	-0.3	0.1	0.0	-0.7	-1.4	-1.0	-1.0	-0.5	-1.0	-0.4	-0.6	-1.1	-3.3	-0.1
Financial difficulties in last 2 years	1.0	1.3	3.4	1.9	1.1	1.5	1.3	0.1	1.5	1.0	0.9	-0.1	1.5	1.0	1.1	1.2	1.2	0.9	1.0	1.1	0.9	-0.7
Number of full brothers	1.0	1.3	7.8	0.8	0.9	0.7	1.0	-1.9	-0.3	1.5	0.0	2.8	-1.0	0.8	0.9	0.9	1.0	0.5	1.0	0.7	1.3	0.2
Medication for pain relief, constipation, heartburn	1.0	1.7	5.2	0.9	1.3	1.9	1.4	0.6	1.1	2.3	1.6	1.7	1.0	1.3	1.3	1.3	1.4	-0.3	1.7	1.2	0.2	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.1	1.4	1.2	1.0	1.4	0.8	1.3	0.7	0.9	-0.3	1.3	1.2	1.3	1.5	1.3	1.3	1.0	1.0	0.6	0.7
Medication: Aspirin	1.0	1.3	2.7	-1.1	-1.4	-1.0	-1.3	-0.8	-0.9	-0.7	-1.6	-1.1	-0.8	-1.4	-1.4	-1.0	-1.4	0.4	-1.1	-1.3	-1.3	-1.0
Medication: Aspirin	1.0	1.3	2.5	-1.2	-1.4	-1.1	-1.4	-0.6	-0.8	-0.7	-1.6	-0.8	-0.8	-1.4	-1.4	-1.0	-1.4	0.4	-1.2	-1.3	-1.2	-0.9
Average weekly champagne plus white wine intake	1.0	1.4	3.0	1.1	1.3	1.0	1.2	0.6	1.2	1.2	1.7	1.3	0.8	1.3	1.3	1.3	1.2	0.9	1.4	1.5	0.8	-0.5
Medication: Lisinopril	1.0	1.3	4.3	-1.5	-1.3	-1.6	-1.3	0.8	-1.1	-1.0	-0.8	-0.3	-2.1	-1.2	-1.3	-0.9	-1.4	0.1	-1.1	-1.2	-0.2	0.3
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.7	-1.2	-1.0	-1.0	-1.0	-0.7	-1.1	-0.1	-1.2	0.6	-1.9	-0.8	-0.9	-0.9	-0.9	0.1	-0.6	-0.9	-1.6	-0.5
Supplements: Zinc	0.9	0.9	2.9	-1.6	-1.0	-0.9	-0.9	-0.3	-1.1	-0.7	-1.0	-0.0	0.1	-0.9	-1.0	-0.8	-0.9	-1.1	-0.9	-1.1	1.7	0.8
Medication: Levothyroxine sodium	0.9	1.6	3.0	1.5	1.4	1.5	1.2	-1.3	1.5	0.8	1.5	-0.1	1.2	1.4	1.3	1.3	1.2	0.2	1.2	1.3	-1.2	1.7
Hair/balding pattern: Pattern 2	0.9	1.1	4.7	-1.2	-1.1	-1.1	-1.2	-0.3	-0.6	-0.6	-0.8	-0.8	-0.6	-0.9	-1.1	-1.1	-1.2	1.3	-0.8	-1.0	-2.2	0.3
Impedance of arm (right)	0.9	4.1	7.2	1.9	2.3	1.9	2.7	1.2	1.5	1.3	2.0	1.0	2.1	2.1	2.4	2.4	2.7	1.8	1.8	1.9	2.6	2.0
Happiness	0.9	1.0	3.1	0.5	1.0	0.9	1.1	1.1	1.4	1.3	1.1	-0.5	1.8	1.0	1.0	0.8	1.0	0.6	1.2	1.1	-0.1	0.5
Age at last live birth	0.9	1.3	2.2	0.9	1.4	0.8	1.3	-0.4	0.8	0.0	1.2	1.1	0.9	1.3	1.4	1.4	1.2	-1.5	0.9	1.4	0.9	1.5
Average weekly red wine intake	0.9	1.4	2.9	-0.8	-1.5	-1.2	-1.4	-0.8	-0.8	0.1	-1.2	-1.3	-0.3	-1.6	-1.5	-1.3	-1.2	-1.1	-0.9	-1.6	-1.7	0.5
Mood swings	0.9	1.6	5.3	-1.0	-1.4	-1.3	-1.4	0.8	-0.3	-0.9	-0.7	-1.0	-2.3	-1.1	-1.4	-1.6	-1.4	-1.0	-1.3	-1.4	-1.3	-1.4
Long-standing illness, disability or infirmity	0.9	1.4	3.2	0.9	1.2	1.1	1.2	0.5	1.6	0.9	1.2	-1.8	1.5	1.2	1.2	1.3	1.2	1.2	1.0	1.1	-0.7	0.9
Hearing aid user	0.9	1.0	2.4	-1.6	-1.0	-1.0	-1.1	-1.0	-1.3	-0.5	-1.1	1.2	-0.8	-1.1	-1.0	-0.7	-1.3	-0.3	-0.8	-0.9	0.8	1.2
Number of operations (self-reported)	0.9	1.4	4.1	1.4	0.9	1.2	0.9	1.6	1.8	0.5	1.3	-2.0	2.0	1.0	0.9	1.0	0.9	0.1	0.7	0.7	-0.8	-0.3
Alzheimer’s Disease (in mother)	0.8	0.9	3.9	-0.9	-0.9	-1.0	-1.0	0.5	-0.6	-0.8	-0.8	-0.6	-1.0	-0.7	-0.9	-1.3	-1.0	-1.1	-0.9	-0.8	-2.0	0.6
Heel T-Score	0.8	6.7	78.5	-0.9	-1.0	-0.8	-0.9	8.9	-0.8	-0.6	1.1	1.9	-1.9	-1.1	-1.0	0.2	-0.9	-3.3	-0.9	-1.2	-3.2	3.0
Systolic Blood Pressure	0.8	4.1	7.3	-2.1	-2.5	-2.5	-2.5	1.2	-1.5	-1.0	-2.1	0.0	-1.7	-2.4	-2.5	-2.7	-2.6	-0.7	-1.9	-2.5	-2.1	-1.2
Current tobacco smoking	0.8	1.3	5.4	0.5	1.0	0.8	1.1	-0.2	1.0	1.2	1.0	-0.4	1.7	0.9	1.0	0.9	1.1	1.6	1.1	0.9	2.3	-1.5
Trunk fat-free mass	0.8	4.6	8.0	-2.4	-2.5	-2.0	-2.8	1.6	-1.6	-1.4	-1.9	-1.5	-1.9	-2.5	-2.6	-2.5	-2.8	-0.9	-2.0	-2.1	-2.1	-2.5
Pulse wave reflection index	0.8	1.0	3.0	-0.4	-0.7	-0.9	-0.8	-1.7	-0.9	-1.6	-1.0	1.0	-1.6	-0.8	-0.7	-1.2	-0.7	-0.7	-1.1	-0.8	-1.0	0.2
Arm fat-free mass (right)	0.8	4.0	10.8	-1.9	-2.1	-1.8	-2.4	2.2	-1.1	-1.0	-1.3	-1.7	-1.3	-2.0	-2.1	-1.9	-2.3	-1.6	-1.6	-1.7	-3.3	-3.0
Wheeze or whistling in the chest in last year	0.8	1.4	3.0	0.9	1.0	1.5	1.0	0.9	1.5	1.7	1.2	-0.5	1.4	1.1	1.0	1.7	1.0	1.4	1.3	1.0	0.7	-0.4
Number of children fathered	0.8	0.9	2.0	-0.6	-1.1	-0.9	-1.1	-0.9	-0.9	-0.6	-1.0	0.9	-1.4	-1.0	-1.1	-1.0	-1.3	-0.6	-0.8	-1.0	-0.5	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	3.3	-1.8	-1.0	-0.6	-0.8	0.1	-1.1	-1.0	-1.3	1.2	-1.5	-0.9	-1.0	-0.8	-0.7	-0.0	-1.1	-1.3	0.2	-0.3
Smoking status: Current	0.8	1.3	5.4	0.6	1.1	0.8	1.2	-0.1	1.1	1.0	1.0	-0.5	1.7	0.9	1.1	1.0	1.2	1.0	1.0	0.9	2.3	-1.5
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.7	1.3	1.0	1.2	1.0	1.0	1.6	0.8	1.3	0.3	1.2	0.8	1.0	1.3	1.0	0.9	0.9	1.0	-0.1	0.1
Arm fat-free mass (left)	0.8	3.9	6.6	-2.1	-2.3	-2.0	-2.5	1.6	-1.4	-1.2	-1.7	-1.4	-1.4	-2.3	-2.3	-2.2	-2.5	-1.4	-1.8	-2.0	-2.6	-2.3
Impedance of whole body	0.8	4.3	7.0	2.0	2.3	1.9	2.7	2.4	1.9	1.4	2.4	0.5	2.3	2.2	2.4	2.6	2.6	1.5	1.9	2.1	1.0	1.6
Arm predicted mass (left)	0.8	4.0	6.5	-2.0	-2.3	-1.9	-2.5	1.4	-1.4	-1.3	-1.8	-1.4	-1.4	-2.3	-2.4	-2.2	-2.5	-1.5	-1.9	-2.0	-2.5	-2.3
Neuroticism (Nagel 2018)	0.7	1.7	10.4	-0.7	-1.1	-0.9	-1.2	2.0	0.9	-0.7	0.0	-3.2	-0.3	-0.8	-1.1	-0.8	-1.2	-1.1	-0.9	-1.0	-2.1	-0.8
Worry (Nagel 2018)	0.7	1.5	4.9	1.0	0.8	0.8	0.9	1.5	2.1	0.7	1.7	-2.2	2.0	0.9	0.9	1.1	0.9	-0.5	0.9	0.8	-1.0	0.1
HDL Cholesterol	0.7	1.2	4.2	-1.2	-1.0	-1.5	-0.9	-0.2	-0.6	-1.4	-0.6	-0.8	-1.0	-0.9	-0.9	-0.9	-1.0	2.1	-1.1	-0.9	-1.9	0.4
Medication: Metformin	0.7	1.0	3.4	-1.4	-0.9	-1.0	-0.9	1.0	-0.8	-0.4	-1.0	-1.1	-1.2	-0.9	-0.9	-0.6	-0.9	-0.9	-0.8	-0.8	-1.8	-0.8
High blood pressure (mother)	0.7	0.9	3.2	1.5	0.9	0.8	0.8	-1.3	1.0	-0.1	0.7	-0.8	0.0	0.8	0.8	0.6	0.8	-1.7	0.5	0.9	1.8	-0.2
Had menopause	0.7	0.8	2.3	0.3	-0.8	-0.9	-0.8	1.3	0.3	-1.5	-0.3	-1.0	-0.7	-0.8	-0.7	-0.6	-0.9	-1.5	-1.0	-0.6	-0.5	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	2.7	0.7	1.0	1.2	0.8	0.0	1.6	1.6	1.1	-1.4	0.8	1.3	0.9	1.2	0.9	1.1	1.4	0.9	-0.7	-0.6
Noisy workplace	0.7	0.9	3.3	-1.1	-0.8	-0.9	-0.8	-0.3	-1.0	-0.7	-0.9	1.0	-1.7	-1.0	-0.8	-0.4	-0.9	-0.4	-0.8	-0.8	1.8	-0.8
Trunk predicted mass	0.7	4.2	7.3	-2.3	-2.4	-1.9	-2.7	1.6	-1.6	-1.3	-1.8	-1.4	-1.8	-2.4	-2.5	-2.3	-2.6	-0.9	-1.9	-2.0	-2.1	-2.4
Exposure to tobacco smoke at home	0.7	0.8	3.4	0.3	0.7	1.4	0.7	0.2	0.8	1.8	0.6	-0.2	0.9	0.7	0.6	1.1	0.7	0.9	1.1	0.7	0.5	-1.4
Gout (self-reported)	0.7	1.0	5.2	-0.6	-0.6	-0.4	-0.5	-2.3	-0.5	0.4	-1.1	-2.0	0.2	-0.6	-0.6	-0.5	-0.4	-1.6	-0.2	-0.8	1.5	-0.3
Arm predicted mass (right)	0.7	3.6	9.4	-1.8	-2.0	-1.7	-2.3	2.1	-1.1	-1.0	-1.3	-1.3	-1.3	-2.0	-2.1	-1.8	-2.2	-1.4	-1.5	-1.6	-3.0	-3.1
Overall health rating	0.7	1.5	2.8	1.0	1.3	1.1	1.3	0.4	1.6	1.2	1.7	-0.6	1.3	1.4	1.4	1.3	1.2	1.3	1.4	1.4	0.9	-0.3
Medication: Paracetamol	0.7	1.1	2.1	1.5	1.1	1.1	1.1	-0.8	1.1	1.2	0.7	-1.1	0.9	1.1	1.1	1.2	1.2	-0.4	1.1	0.9	0.5	-1.1
Ever had prostate specific antigen (PSA) test	0.7	0.8	3.9	0.5	0.7	0.1	0.6	1.4	1.1	0.3	1.0	-2.0	1.4	0.9	0.8	0.6	0.5	0.3	0.7	0.7	-0.6	0.1
Schizophrenia (2018)	0.6	1.1	2.5	-0.7	-1.2	-1.3	-1.0	0.6	-0.6	-1.1	-0.8	-1.5	0.4	-1.2	-1.2	-0.8	-0.9	-1.3	-1.3	-1.4	0.2	-1.6
Lupus	0.6	0.9	2.5	0.8	0.9	0.7	0.9	0.1	1.6	1.3	0.8	-1.5	1.0	0.8	0.9	0.9	0.9	1.0	1.1	0.8	-0.0	0.8
Systolic blood pressure, automated reading	0.6	1.8	5.5	-1.1	-1.5	-1.6	-1.5	0.8	-0.6	-0.5	-1.1	-0.1	-1.0	-1.3	-1.4	-1.4	-1.5	-1.2	-1.0	-1.4	-2.4	-2.1
Age when periods started (menarche)	0.6	1.4	2.6	1.2	1.4	1.6	1.4	-0.6	0.9	1.1	1.1	1.2	0.4	1.4	1.4	1.3	1.4	-1.1	1.3	1.3	-0.5	-1.0
Pain all over the body in last month	0.6	0.7	4.1	-0.7	-0.3	-0.3	-0.3	-1.6	-1.3	0.6	-0.6	1.3	-0.8	-0.3	-0.4	-0.2	-0.3	2.0	0.0	-0.4	-0.2	-0.1
Medication: Ramipril	0.6	0.7	3.8	0.7	0.6	0.3	0.5	2.0	1.1	0.3	0.5	-0.3	0.4	0.8	0.6	0.3	0.5	0.4	0.6	0.7	-1.3	-1.7
Headache pain in last month	0.6	1.0	3.2	1.0	0.9	1.1	1.0	0.5	1.4	1.8	0.7	-1.1	1.2	0.8	0.9	0.7	1.1	-0.7	1.2	0.6	0.2	1.1
Exposure to tobacco smoke outside home	0.6	0.8	3.6	-0.4	-0.9	-0.4	-0.8	1.6	-0.1	0.2	-0.5	-1.2	0.1	-0.8	-0.9	-0.7	-0.8	-1.0	-0.6	-1.0	-1.0	-1.9
Comparative body size at age 10	0.6	1.6	8.5	1.2	1.3	1.1	1.3	-2.9	1.0	1.2	0.7	-0.0	1.0	1.3	1.3	0.9	1.4	0.6	1.3	1.0	1.1	1.3
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.9	-1.0	-0.9	-0.5	-0.9	-0.4	-0.9	-0.8	-0.7	0.7	-1.4	-0.9	-0.9	-0.9	-0.8	0.1	-0.9	-1.0	-0.5	1.0
Knee pain experienced in last month	0.6	0.9	8.2	-0.5	-0.5	-1.0	-0.6	2.9	0.4	-1.0	-0.1	-1.6	0.5	-0.5	-0.5	-0.2	-0.7	-0.8	-0.6	-0.3	-1.2	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	6.6	-1.6	-1.2	-1.2	-1.1	2.6	-1.1	0.1	-0.8	-0.3	-1.4	-1.3	-1.2	-1.0	-1.0	0.5	-0.7	-1.2	-0.3	-0.4
Whole body fat-free mass	0.6	3.3	6.7	-2.1	-2.0	-1.7	-2.4	1.6	-1.4	-1.0	-1.5	-1.1	-1.4	-2.1	-2.1	-2.0	-2.3	-0.9	-1.6	-1.7	-1.8	-2.6
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	3.6	0.1	0.5	0.7	0.7	0.6	0.2	1.6	0.2	-0.8	0.7	0.6	0.5	0.4	0.8	1.1	0.8	0.3	-0.1	-1.9
Breast cancer (self-reported)	0.6	0.7	3.0	0.8	0.9	0.8	0.9	1.5	0.3	-0.5	0.6	-0.5	0.5	0.8	0.9	0.9	0.9	0.9	0.3	0.7	1.7	0.1
Medication: Gliclazide	0.6	0.7	2.0	0.4	0.7	1.0	0.9	0.8	0.8	1.4	0.4	-0.6	0.6	0.6	0.7	0.9	0.9	-1.2	0.9	0.5	0.0	-1.0
Illnesses of father: High blood pressure	0.6	0.8	3.5	-0.4	-0.6	-0.3	-0.9	1.2	0.5	-0.1	-0.1	-1.9	-1.2	-0.5	-0.7	-0.6	-0.7	-0.7	-0.3	-0.3	1.3	-1.8
Ever smoked	0.6	1.1	4.4	-2.0	-1.0	-1.0	-1.1	0.1	-0.1	0.5	-0.5	-2.1	-0.1	-0.8	-1.0	-1.1	-1.2	0.9	-0.4	-1.0	-1.3	-0.4
Cholesterol lowering medication	0.6	0.9	3.0	-0.9	-0.9	-0.6	-1.0	1.2	0.1	-0.2	-0.1	-0.2	-1.7	-0.9	-0.9	-1.3	-0.9	1.0	-0.7	-0.7	-0.7	-1.7
Alzheimer’s Disease (in father)	0.5	0.5	2.6	0.3	0.5	0.7	0.6	-0.2	0.7	1.1	0.3	-1.6	0.4	0.6	0.6	0.4	0.7	-1.2	0.8	0.6	-0.2	0.3
Major Depression (MDD)	0.5	0.7	2.1	-1.2	-0.9	-0.2	-1.0	0.3	-0.4	0.2	-0.7	-1.1	0.0	-1.0	-1.0	-0.7	-1.0	0.5	-0.6	-1.1	-0.4	-1.5
Reaction Time	0.5	0.9	5.2	-0.8	-0.9	-0.8	-1.0	-2.3	-1.1	0.0	-0.9	1.0	-0.7	-1.0	-0.9	-0.9	-0.9	-1.0	-0.5	-1.0	0.1	0.4
Prostate Cancer	0.5	0.7	2.0	-0.4	-1.0	-0.8	-1.0	-0.1	-0.6	-0.8	-1.0	0.2	-1.4	-1.0	-1.0	-0.7	-1.1	-1.0	-1.0	-1.0	0.4	-0.7
Age at First Birth	0.5	0.7	2.5	0.5	1.0	0.4	1.1	0.2	0.4	0.4	0.7	0.5	0.6	0.9	1.0	0.6	1.1	1.6	0.7	0.9	0.2	1.5
Mean Putamen Volume	0.5	0.6	9.7	0.2	0.2	0.2	0.0	-3.1	-0.0	-0.2	0.0	0.4	0.3	0.2	0.1	-0.2	0.1	-0.2	0.0	0.3	0.1	0.4
Triglycerides	0.5	0.8	3.1	1.2	0.5	1.2	0.5	-1.0	0.2	0.5	0.3	1.8	-0.3	0.3	0.5	0.5	0.5	-1.6	0.5	0.4	1.8	1.0
Lung FEV1/FVC ratio	0.5	2.4	5.8	-2.4	-1.8	-2.0	-1.8	1.8	-0.8	-1.4	-0.9	-1.1	-0.8	-1.6	-1.7	-1.9	-1.9	0.9	-1.5	-1.5	-2.0	-0.1
Number of treatments/medications taken	0.5	0.8	6.0	1.0	0.7	0.2	0.8	0.0	1.4	-0.2	0.7	-2.5	0.5	0.8	0.8	0.9	0.8	0.9	0.4	0.6	-1.1	0.1
Pack years adult smoking proportion	0.5	0.7	5.6	-0.5	-0.6	-0.7	-0.5	-0.4	-0.7	0.5	-0.7	0.0	-0.8	-0.6	-0.6	-0.1	-0.5	-0.3	-0.2	-0.7	1.8	-2.4
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	3.2	-0.0	-0.5	-0.6	-0.5	-0.4	-0.3	-0.7	-1.0	1.3	-0.8	-0.5	-0.5	-0.7	-0.5	0.6	-0.7	-0.7	-0.2	1.8
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	5.7	-0.4	-0.2	-0.4	-0.0	2.2	0.1	-0.3	0.2	-0.6	-0.4	-0.2	-0.2	-0.0	-0.1	0.4	-0.3	-0.3	-2.4	0.6
Past tobacco smoking	0.5	1.0	4.2	1.2	1.0	0.8	1.1	-0.9	-0.2	-0.3	0.6	1.7	0.6	0.8	1.0	1.0	1.2	0.1	0.4	1.0	2.1	0.5
Nervous feelings	0.5	1.0	3.0	0.5	0.7	0.7	0.7	1.6	1.7	0.8	1.7	-1.4	1.3	0.9	0.7	0.7	0.7	1.0	0.8	0.7	-0.5	0.4
Had other major operations	0.5	0.7	5.8	-0.6	-0.5	-0.0	-0.4	0.3	0.2	0.5	-0.6	-2.4	0.7	-0.4	-0.5	-0.3	-0.3	-1.2	-0.2	-0.7	-0.6	-1.4
Mouth/teeth dental problems	0.5	0.7	3.0	0.8	0.7	0.9	0.7	-1.7	0.1	0.8	0.3	1.6	0.2	0.6	0.7	0.4	0.7	-1.4	0.8	0.7	-0.4	0.2
Time employed in main current job	0.5	0.5	3.5	0.4	0.4	0.3	0.6	-1.8	0.4	-0.3	-0.0	0.1	-0.3	0.3	0.4	0.1	0.7	-1.9	0.0	0.2	-0.0	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	7.2	-0.6	-0.0	-0.3	-0.3	0.6	0.1	-0.3	-0.1	-2.7	0.5	0.0	-0.1	-0.1	-0.2	-0.7	-0.1	0.1	0.7	-1.4
Lung cancer (father)	0.5	0.6	4.9	0.7	0.4	0.5	0.4	0.4	0.8	0.3	0.8	-0.3	0.1	0.5	0.4	0.4	0.4	2.2	0.4	0.4	-0.4	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	3.1	1.5	0.6	1.1	0.5	0.8	1.7	0.9	0.9	-1.0	0.7	0.7	0.5	0.8	0.6	-0.3	0.7	0.5	-0.9	-1.2
Medication: Paracetamol	0.5	0.9	1.8	1.3	1.2	0.9	1.1	-0.6	0.8	0.7	0.8	-0.3	0.5	1.2	1.1	1.0	1.1	-0.3	1.0	1.1	0.9	-1.1
Pulse wave peak to peak time	0.5	0.5	3.7	0.1	0.3	0.6	0.4	1.7	0.4	1.1	0.6	-0.0	0.1	0.3	0.3	0.6	0.4	0.1	0.6	0.3	1.9	0.3
Qualifications: College or University degree	0.5	1.6	4.4	-1.1	-1.3	-1.2	-1.2	-0.6	-0.7	-1.2	-1.3	-1.6	-0.9	-1.4	-1.3	-1.3	-1.2	-0.9	-1.3	-1.4	-1.4	2.1
Medication: Ibuprofen	0.5	0.6	7.6	-0.1	0.3	0.1	0.1	-0.0	0.5	-0.4	0.2	-2.8	1.0	0.3	0.2	0.4	0.2	-0.9	0.0	0.3	0.2	-1.1
Medication: Allopurinol	0.5	0.6	5.8	-0.3	-0.0	-0.3	-0.2	-2.4	-0.2	0.1	-0.4	-1.5	1.1	0.1	-0.0	-0.1	-0.2	-1.1	0.2	0.0	0.3	0.8
Number of full sisters	0.5	0.6	2.9	-0.0	-0.4	-0.7	-0.2	0.4	-0.8	-0.2	-1.0	0.6	-1.3	-0.5	-0.4	-0.4	-0.1	0.4	-0.5	-0.7	-1.4	-1.7
Suffer from ‘nerves’	0.5	0.8	4.3	0.9	0.4	0.8	0.3	1.4	1.5	1.0	1.2	-2.1	0.8	0.5	0.4	0.4	0.4	-0.5	0.7	0.4	-0.2	-0.9
Commuting to job workplace: Car/motor vehicle	0.5	0.6	3.7	0.3	0.4	0.6	0.5	1.3	0.9	0.7	0.7	-0.4	1.4	0.5	0.4	-0.0	0.4	0.5	0.5	0.5	-0.1	-1.9
Illnesses of siblings: Diabetes	0.5	0.6	1.8	-0.5	-0.8	-0.4	-0.9	-0.2	-0.5	0.1	-0.8	-0.2	-1.2	-0.7	-0.8	-1.1	-0.8	-0.6	-0.4	-0.6	-1.3	-1.2
Loneliness, isolation	0.5	0.7	4.8	0.1	-0.5	-0.2	-0.6	2.0	0.7	1.0	0.3	-0.6	-0.3	-0.2	-0.6	-0.5	-0.7	-0.5	0.2	-0.5	0.4	-2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.4	0.4	-0.5	-0.8	-0.2	1.5	0.1	-1.5	-0.0	-0.3	-0.6	-0.5	-0.4	-0.2	-0.4	0.5	-1.0	-0.7	-0.5	1.5
Whole body water mass	0.5	3.0	6.4	-1.9	-1.9	-1.6	-2.2	1.4	-1.3	-0.9	-1.5	-1.0	-1.3	-2.0	-2.0	-1.9	-2.2	-1.0	-1.5	-1.6	-1.8	-2.5
Commuting to job workplace: Public transport	0.5	0.6	2.6	0.6	0.7	0.7	0.6	-1.6	-0.1	0.1	0.4	0.5	0.1	0.7	0.7	1.1	0.7	0.8	0.5	0.7	1.3	0.9
Basal metabolic rate	0.5	2.7	7.3	-1.8	-1.8	-1.6	-2.1	1.7	-1.2	-0.8	-1.4	-1.1	-1.1	-1.9	-1.9	-1.7	-2.0	-0.9	-1.4	-1.6	-1.6	-2.7
Supplements: Calcium	0.5	0.6	3.5	-0.4	-0.6	-0.8	-0.5	-0.9	-0.2	-0.7	-0.6	-1.8	0.3	-0.5	-0.5	-0.2	-0.5	-1.9	-0.6	-0.5	0.1	-0.0
Pack years of smoking	0.5	0.8	4.2	-0.6	-0.8	-0.8	-0.7	-0.6	-0.9	0.5	-1.0	0.1	-1.1	-0.9	-0.8	-0.3	-0.8	-0.0	-0.4	-0.9	1.4	-2.0
Intelligence (Savage-Jansen 2018)	0.4	1.2	8.0	-2.8	-1.0	-0.8	-1.0	-0.8	-1.2	0.3	-1.2	0.4	-0.3	-0.8	-1.0	-1.1	-1.0	2.1	-0.4	-0.7	-0.2	0.3
Alzheimer’s Disease (including proxy)	0.4	0.6	2.0	-0.8	-0.7	-0.7	-0.6	0.5	-0.3	-0.1	-0.7	-1.0	-0.9	-0.4	-0.6	-0.9	-0.6	-1.0	-0.4	-0.7	-1.4	0.8
Irritable Bowel Disease (IBD)	0.4	0.8	2.7	1.7	1.0	1.2	1.0	-0.4	1.1	0.9	1.1	-0.5	0.4	1.0	1.0	0.8	1.0	0.9	1.0	0.9	0.5	-0.1
Bipolar Disorder (2011)	0.4	0.4	3.3	0.4	-0.0	0.1	0.1	-0.6	-0.6	-0.8	-0.2	1.0	-0.2	-0.0	0.0	0.5	0.1	-0.6	-0.4	-0.1	0.5	-1.8
LDL Cholesterol	0.4	0.7	5.3	0.3	0.5	0.6	0.4	-1.0	-0.1	1.1	0.4	1.4	-0.1	0.6	0.5	0.7	0.3	0.2	0.9	0.6	2.3	-0.2
Primary Biliary Cirrhosis	0.4	0.6	7.5	0.1	-0.2	-0.1	0.1	2.7	0.7	-0.4	0.1	-1.1	0.3	-0.1	-0.2	0.2	-0.1	1.0	-0.4	-0.5	-0.9	-0.2
Schizophrenia (2014)	0.4	0.9	1.6	-0.4	-1.1	-1.0	-0.9	0.8	-0.8	-1.0	-0.8	-0.7	0.1	-1.2	-1.1	-0.7	-0.9	-1.0	-1.2	-1.2	0.6	-1.3
Ulcerative Colitis	0.4	0.6	1.5	0.6	-0.8	-0.9	-0.6	-0.3	-0.6	-1.0	-1.1	0.4	-0.9	-0.8	-0.8	-0.7	-0.6	-1.2	-1.0	-1.2	-0.2	0.6
Lung FVC	0.4	2.0	8.1	1.1	1.4	1.8	1.2	-2.8	1.3	1.1	1.6	0.2	0.7	1.6	1.4	1.1	1.4	1.1	1.4	1.5	1.4	0.6
Sensitivity / hurt feelings	0.4	0.8	4.0	-0.3	-0.3	-0.3	-0.6	2.0	0.9	-0.7	0.9	-1.8	0.6	-0.0	-0.4	-0.2	-0.6	-0.0	-0.3	-0.2	-1.8	0.4
Medication for hormone replacement therapy	0.4	0.5	2.8	-0.3	-0.6	-0.1	-0.6	-0.1	0.2	-1.0	-0.1	-0.9	-0.2	-0.5	-0.5	-0.2	-0.8	0.6	-0.7	-0.4	-1.2	1.7
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	4.0	0.6	-0.4	-0.4	-0.3	2.0	0.4	-1.0	0.2	-1.0	0.3	-0.3	-0.3	-0.2	-0.4	-0.6	-0.6	-0.4	-0.2	0.2
Serious illness, injury or assault to yourself	0.4	0.5	3.7	-0.6	-0.3	-0.2	-0.2	1.9	-0.2	-0.0	-0.3	-1.0	-0.0	-0.1	-0.2	-0.1	-0.2	1.2	-0.1	-0.2	0.1	-1.5
Waist circumference	0.4	1.5	3.9	-1.5	-1.4	-1.7	-1.6	0.4	-0.9	-0.7	-1.2	-1.2	-0.5	-1.3	-1.5	-1.0	-1.6	-0.4	-1.1	-1.4	-0.4	-2.0
Diabetes (self-reported)	0.4	0.6	3.6	-1.0	-0.4	-0.4	-0.5	0.3	0.0	0.6	-0.2	-1.1	-0.7	-0.4	-0.4	-0.3	-0.4	-1.9	0.0	-0.2	-0.7	-1.7
Falls in the last year	0.4	0.5	2.3	-0.5	-0.7	-0.4	-0.8	-1.2	-0.7	-0.1	-0.8	1.5	-0.3	-0.7	-0.7	-0.5	-0.8	0.6	-0.4	-0.5	1.0	-0.4
Hair/balding pattern: Pattern 3	0.4	0.6	5.1	-0.3	0.1	-0.1	0.2	2.3	0.2	-0.1	0.3	1.6	-0.7	0.2	0.2	-0.1	0.1	0.7	0.1	0.2	-0.1	-1.3
Pulse rate	0.4	0.7	3.3	-0.5	-0.9	-0.9	-0.9	-0.5	-0.5	-0.8	-0.4	-1.8	0.2	-0.8	-0.8	-0.7	-0.8	-0.4	-0.9	-0.9	-1.1	0.2
Mouth/teeth dental problems: Dentures	0.4	0.7	7.1	-0.5	-0.2	-0.1	-0.2	1.4	0.6	-0.4	0.7	-2.7	-0.1	-0.1	-0.2	0.2	-0.3	1.6	-0.3	-0.1	0.8	-0.0
Depression (self-reported)	0.4	0.4	2.6	0.5	0.4	0.4	0.1	0.3	1.2	-0.3	0.8	-1.6	0.8	0.5	0.4	-0.0	0.2	-0.5	0.2	0.6	1.2	0.1
Prospective memory result	0.4	0.5	3.5	0.2	0.6	0.5	0.4	0.5	0.2	0.7	0.4	0.6	1.2	0.5	0.5	0.7	0.4	1.9	0.7	0.7	0.7	-0.4
Illnesses of mother	0.4	0.5	1.7	-1.1	-0.5	-0.7	-0.5	0.8	-1.0	0.3	-0.5	1.3	0.5	-0.7	-0.5	-0.4	-0.4	1.2	-0.2	-0.5	0.0	1.1
Pulse wave Arterial Stiffness index	0.4	0.5	4.3	-0.1	-0.3	-0.6	-0.4	-1.4	-0.4	-1.0	-0.6	0.1	-0.2	-0.2	-0.3	-0.5	-0.3	-0.1	-0.6	-0.2	-2.1	-0.4
Breastfed as a baby	0.4	0.5	3.1	-0.1	0.3	0.8	0.3	-1.0	0.3	1.8	-0.2	-0.4	0.4	0.3	0.2	0.3	0.2	-0.8	0.8	0.4	0.2	-1.5
Hair/balding pattern: Pattern 4	0.4	0.9	6.7	0.6	0.8	0.8	0.8	-0.1	0.1	0.9	0.6	0.7	1.4	0.7	0.8	1.2	0.6	0.7	0.8	0.8	2.6	-0.5
Loud music exposure frequency	0.4	0.4	4.0	0.1	0.1	0.2	0.0	-2.0	-0.5	-0.5	-0.2	0.8	-0.6	0.0	0.1	0.2	-0.0	-0.4	-0.1	0.1	-0.0	1.5
Medication: Amlodipine	0.4	0.5	3.9	0.7	0.7	0.7	0.8	-0.0	0.1	0.5	0.1	0.4	0.5	0.6	0.7	0.9	0.8	0.3	0.5	0.6	0.5	-2.0
Forced vital capacity (FVC), Best measure	0.4	1.4	3.0	0.7	1.4	1.7	1.2	-0.2	1.1	1.3	1.7	0.6	0.9	1.4	1.3	1.2	1.3	1.0	1.4	1.4	0.9	0.2
Emphysema/chronic bronchitis	0.4	0.4	1.4	1.2	0.6	0.6	0.7	-0.2	0.8	0.9	0.4	1.0	0.4	0.5	0.6	0.8	0.6	-0.6	0.8	0.6	0.1	0.2
Medication: Blood pressure	0.4	0.7	3.0	-0.4	-0.8	-1.1	-0.6	-0.1	-0.8	-0.9	-1.1	-0.5	-0.3	-0.9	-0.7	-0.5	-0.7	-1.7	-0.9	-0.9	-0.9	0.1
Mean time to correctly identify matches	0.4	0.7	2.9	-0.7	-0.8	-1.0	-0.8	-1.7	-0.9	-0.2	-0.8	1.2	-0.9	-0.8	-0.8	-0.9	-0.8	-0.5	-0.5	-0.9	-0.1	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	3.3	0.8	0.5	0.8	0.5	-1.8	0.3	0.0	-0.2	-0.6	-0.1	0.3	0.4	0.4	0.5	-0.6	0.3	0.3	1.7	0.5
Ever had bowel cancer screening	0.4	0.5	2.2	-0.2	-0.4	-0.9	-0.4	-0.2	-0.2	-1.5	-0.0	0.0	-0.5	-0.4	-0.4	-0.7	-0.4	0.9	-0.9	-0.5	-1.1	1.4
Illnesses of father: None of the above (group 1)	0.4	0.5	4.8	0.2	0.0	-0.1	0.1	-1.3	-0.7	-0.2	-0.2	2.2	0.2	-0.1	0.1	-0.0	0.0	-0.3	-0.1	-0.1	-1.4	0.9
Medication: Atorvastatin	0.4	0.5	1.2	-1.1	-0.7	-0.5	-0.8	-0.5	-0.6	-0.9	-0.6	1.0	-1.1	-0.5	-0.7	-0.9	-0.7	0.3	-0.8	-0.5	-0.4	-0.8
Average weekly beer plus cider intake	0.4	0.5	2.3	-0.6	-0.6	-0.2	-0.5	-1.2	-0.8	-0.7	-0.4	0.5	-1.0	-0.5	-0.6	-0.5	-0.5	-1.5	-0.6	-0.5	0.5	-0.9
Irritability	0.4	0.6	3.2	0.2	-0.3	-0.2	-0.3	1.8	0.4	-0.3	-0.2	-1.3	-0.1	-0.1	-0.3	-0.4	-0.2	-1.5	-0.4	-0.5	-1.3	-1.3
Age started oral contraceptive pill	0.4	0.5	1.2	1.0	0.7	0.4	0.7	-0.1	0.9	0.0	0.6	1.1	0.6	0.8	0.8	0.8	0.8	-0.2	0.5	0.8	-0.6	0.6
Unable to work because of sickness or disability	0.4	0.5	3.2	-0.0	0.4	0.9	0.5	1.2	0.4	0.4	0.4	-1.2	0.4	0.4	0.4	0.7	0.5	1.8	0.4	0.2	0.2	-0.9
Commuting to job workplace: Cycle	0.4	0.5	5.2	-0.9	0.1	0.2	0.3	-0.5	-0.1	1.1	0.0	-0.0	-0.2	-0.0	0.2	0.1	0.2	0.2	0.6	0.1	0.8	2.3
Alcohol drinker status: Previous	0.4	0.5	2.7	-0.5	-0.6	-0.4	-0.4	-0.1	-0.8	0.0	-0.7	0.3	-1.7	-0.8	-0.6	-0.6	-0.4	-0.0	-0.4	-0.7	-1.3	0.1
Verbal and Numeric Reasoning (VNR)	0.3	0.7	4.7	-1.5	0.2	0.3	0.2	-0.6	-0.4	1.0	-0.3	0.1	0.9	0.3	0.2	-0.2	0.2	2.2	0.5	0.4	0.8	-1.4
Ovarian Cancer	0.3	0.4	2.0	-0.5	-0.5	-0.2	-0.3	-0.8	-0.3	0.3	-1.0	-0.3	-1.4	-0.6	-0.6	-0.2	-0.3	-1.2	-0.3	-0.8	-0.3	-0.5
Crohns Disease (2012)	0.3	0.5	1.5	1.0	0.6	0.4	0.5	-0.6	0.7	-0.5	0.9	-0.9	0.4	0.7	0.6	0.6	0.5	-0.8	0.3	0.7	-0.3	1.2
Fasting Glucose	0.3	0.4	2.5	-0.2	-0.2	0.1	-0.2	0.1	-0.5	-0.1	-0.4	0.5	-1.5	-0.3	-0.2	-0.6	-0.3	-1.6	-0.1	-0.2	-0.7	-0.8
Rheumatoid Arthritis	0.3	0.4	1.0	0.6	0.5	0.9	0.4	-1.0	1.0	0.8	0.3	-0.6	-0.0	0.6	0.5	0.7	0.4	0.7	0.7	0.6	0.5	0.2
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.8	0.9	0.4	0.4	0.3	-0.4	0.2	0.3	-0.0	1.4	0.4	0.3	0.4	0.2	0.4	-1.0	0.4	0.4	0.9	-1.3
Blood White Count	0.3	2.5	4.7	-1.6	-1.7	-1.9	-1.7	-0.5	-1.7	-2.2	-1.6	0.2	-1.6	-1.9	-1.7	-1.7	-1.7	-1.5	-2.0	-1.7	-0.5	1.1
Allergy or Eczema	0.3	0.7	1.4	-1.2	-0.9	-1.1	-0.7	0.4	-0.9	-0.9	-1.0	-0.1	-0.4	-1.0	-0.9	-1.0	-0.7	-0.0	-1.1	-1.1	-0.2	0.9
Hypothyroidism (self reported)	0.3	0.7	1.7	1.3	1.0	1.0	0.8	-0.3	1.1	-0.3	1.2	-0.2	0.7	1.0	1.0	1.0	0.8	-0.3	0.6	1.1	-0.6	0.8
Type 2 Diabetes (T2D) (2018)	0.3	0.6	4.4	-0.5	-0.0	0.2	-0.1	1.8	0.4	1.2	0.3	-0.6	-0.1	0.1	-0.0	0.1	-0.0	-0.9	0.5	0.1	-0.3	-2.1
Impedance of leg (right)	0.3	1.5	3.9	1.3	1.2	1.0	1.4	2.0	1.2	0.5	1.5	-0.0	1.2	1.2	1.3	1.6	1.3	1.4	0.9	1.1	0.2	1.6
Hand grip strength (right)	0.3	0.7	4.7	-0.5	-0.5	-0.4	-0.6	-0.4	-0.6	0.0	-0.5	-0.4	-1.0	-0.5	-0.5	-0.5	-0.5	-0.9	-0.3	-0.3	-2.2	-1.9
Maternal smoking around birth	0.3	0.5	1.5	1.2	0.3	1.0	0.3	-0.5	1.2	1.0	0.3	-1.0	0.8	0.5	0.4	0.4	0.2	-0.5	0.7	0.5	-0.0	-0.7
Relative age voice broke	0.3	0.5	3.0	0.2	0.3	0.8	0.3	-0.4	0.5	1.1	0.1	-1.4	-0.3	0.3	0.2	0.1	0.3	-1.7	0.6	0.3	-0.3	-1.1
Taking other prescription medications	0.3	0.5	4.3	0.3	0.5	0.3	0.5	0.5	1.0	0.1	0.7	-2.1	0.1	0.6	0.5	0.5	0.5	1.1	0.3	0.4	0.0	-0.6
Qualifications: CSEs or equivalent	0.3	0.3	2.7	-0.7	-0.1	-0.2	-0.1	0.9	-0.1	-0.7	0.0	-1.6	0.3	-0.2	-0.2	-0.4	0.0	-1.1	-0.4	-0.0	0.4	-0.1
Sitting height	0.3	1.8	24.8	-0.8	-0.2	-0.3	-0.4	5.0	0.1	-0.3	0.9	-0.6	0.5	-0.4	-0.3	-0.2	-0.3	0.2	-0.2	0.1	-1.6	-2.0
Hearing difficulty/problems with background noise	0.3	0.4	2.2	-0.4	-0.7	-0.4	-0.4	-0.2	0.1	0.3	-0.6	-0.3	-0.1	-0.5	-0.6	-0.8	-0.5	0.5	-0.3	-1.0	-1.2	1.5
Fluid intelligence score	0.3	0.6	2.4	-0.4	0.8	0.5	0.8	-0.5	-0.1	1.3	0.3	0.4	0.8	1.0	0.8	0.2	0.8	1.6	1.0	0.8	-0.2	-1.0
Weight	0.3	1.5	8.3	-1.1	-1.1	-1.3	-1.3	1.9	-0.6	-0.5	-0.8	-1.2	-0.2	-1.1	-1.2	-0.7	-1.2	-0.7	-0.9	-1.0	-0.9	-2.9
Alcohol intake versus 10 years previously	0.3	0.5	6.2	-0.2	0.5	0.2	0.8	2.5	-0.4	0.2	0.2	0.3	0.5	0.5	0.5	0.5	0.6	0.2	0.2	0.2	0.6	-0.8
Number of live births	0.3	0.4	1.4	-0.6	-0.6	-0.8	-0.7	0.3	-0.4	-0.9	-0.5	-0.3	-0.4	-0.5	-0.6	-0.6	-0.7	0.4	-0.7	-0.5	1.2	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	3.2	-0.1	0.3	0.2	0.4	-1.8	0.0	0.7	0.1	-0.8	0.4	0.2	0.2	0.4	0.5	0.0	0.4	0.1	-0.5	1.0
Medication: Cholesterol lowering	0.3	0.4	1.9	-0.1	-0.4	-0.7	-0.3	-1.0	-0.7	-1.4	-0.6	1.1	-0.5	-0.4	-0.3	0.2	-0.3	-0.0	-0.8	-0.4	-0.8	0.2
Arm fat mass (right)	0.3	1.3	5.2	-0.9	-1.2	-1.4	-1.3	0.9	-0.8	-0.4	-1.2	-0.6	-0.4	-1.3	-1.3	-0.9	-1.2	-0.8	-1.0	-1.3	-0.4	-2.3
Tense / ‘highly strung’	0.3	0.5	1.8	0.1	0.3	0.5	0.2	1.1	1.3	0.9	0.8	-1.0	1.2	0.4	0.3	0.2	0.2	-0.9	0.7	0.3	0.1	-0.3
Birth weight of first child	0.3	0.5	4.9	0.9	0.1	-0.1	0.2	0.3	0.2	-0.7	0.3	1.0	-0.1	0.1	0.1	0.2	0.2	-0.6	-0.2	-0.0	-1.0	2.2
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.6	-0.6	-0.5	-0.2	-0.5	0.7	0.4	0.5	-0.4	-1.0	-0.4	-0.4	-0.5	-0.7	-0.5	-0.6	-0.0	-0.4	-0.5	-1.3
High blood pressure (siblings)	0.3	0.4	5.3	0.2	-0.3	-0.1	-0.5	-0.1	0.2	0.3	-0.1	-0.7	-0.5	-0.1	-0.3	-0.5	-0.4	0.0	-0.1	-0.1	0.7	-2.3
Age at first live birth	0.3	0.4	2.5	0.1	0.6	0.2	0.5	-0.5	-0.0	-0.0	0.4	0.9	0.7	0.6	0.6	0.9	0.4	-1.1	0.4	0.7	-0.2	1.6
Alcohol intake frequency.	0.3	0.7	3.8	-0.1	-0.4	-0.6	-0.3	1.4	-1.0	-0.3	-0.5	0.2	-0.8	-0.6	-0.5	-0.1	-0.3	-0.0	-0.5	-0.5	1.9	-1.8
Supplements: Vitamin C	0.3	0.3	0.7	-0.8	-0.6	-0.0	-0.7	0.6	0.1	0.6	0.0	-0.7	0.4	-0.5	-0.7	-0.7	-0.6	-0.7	-0.2	-0.6	0.3	-0.6
Diabetes diagnosed by doctor	0.3	0.4	2.0	-0.2	0.4	0.4	0.3	0.7	0.6	1.3	0.3	-0.6	0.0	0.4	0.3	0.6	0.4	-0.9	0.7	0.5	-0.7	-1.4
Eye problems/disorders: Cataract	0.3	0.4	2.4	0.3	-0.2	-0.2	0.0	0.8	0.3	-0.1	0.1	-0.8	0.5	-0.2	-0.1	0.4	-0.2	-0.5	-0.2	-0.4	-1.4	1.6
Medication for cholesterol	0.3	0.4	3.9	-0.0	-0.0	0.0	-0.0	0.1	-0.5	1.0	-0.4	0.8	0.5	-0.0	-0.0	0.2	0.1	-2.0	0.3	-0.2	0.7	-1.2
Back pain experienced in last month	0.3	0.5	2.8	0.4	-0.6	-0.9	-0.7	1.7	0.0	-1.0	-0.4	-0.3	-0.1	-0.7	-0.7	-0.4	-0.7	-0.3	-0.9	-0.6	0.7	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.5	0.2	0.7	1.1	0.7	0.3	1.2	0.1	1.2	-1.2	0.3	0.9	0.7	0.3	0.8	0.6	0.5	0.7	-0.5	0.9
Guilty feelings	0.3	0.4	5.3	0.7	-0.0	0.2	0.0	0.4	0.8	0.1	-0.0	-0.6	0.1	0.1	-0.0	0.0	-0.0	-2.3	0.0	-0.1	0.1	-0.9
Ever taken oral contraceptive pill	0.3	0.4	2.5	-0.0	-0.4	-0.1	-0.3	-1.6	-0.5	0.7	-0.6	0.8	-0.6	-0.5	-0.3	-0.6	-0.3	-0.5	0.0	-0.4	-0.2	1.1
Medication: Blood pressure	0.3	0.5	1.3	1.1	0.9	0.8	1.0	-0.3	0.8	0.2	0.5	0.6	-0.2	0.9	1.0	0.7	1.0	0.4	0.7	0.9	-0.4	0.1
Bipolar Disorder (2018)	0.2	0.3	3.2	0.9	0.1	0.4	0.3	-0.7	0.2	-0.1	0.3	1.8	-0.4	0.2	0.2	0.9	0.2	-0.2	0.1	-0.1	-0.1	0.3
Bipolar Disorder or Schizophrenia	0.2	0.5	1.3	0.0	-0.9	-0.8	-0.6	0.0	-0.4	-0.9	-0.4	-0.0	0.0	-0.8	-0.8	-0.0	-0.6	-1.1	-1.0	-1.1	0.2	-1.0
Schizophrenia vs Biploar Disorder	0.2	0.3	1.4	0.1	-0.0	-0.1	-0.1	1.1	0.6	0.5	0.2	-1.2	1.2	-0.1	-0.1	-0.0	-0.1	-0.3	0.2	0.1	0.3	-0.1
Ulcerative Colitis (UC)	0.2	0.3	1.5	1.2	0.2	0.5	0.5	-0.6	0.1	0.9	-0.3	1.1	-0.4	0.1	0.2	-0.0	0.5	0.5	0.3	-0.1	0.8	-0.1
Breast Cancer	0.2	0.6	2.2	1.0	0.5	0.5	0.4	1.2	0.9	0.8	0.7	-0.1	0.4	0.6	0.5	0.7	0.4	-0.0	0.7	0.6	-1.5	-1.2
BMI	0.2	0.9	7.0	0.0	-0.7	-0.7	-0.9	-0.8	-0.4	-0.2	-0.9	-1.4	0.8	-0.7	-0.8	-0.5	-0.8	-1.1	-0.5	-0.6	-0.0	-2.6
Smoking Status	0.2	0.5	3.3	-0.9	-0.6	-0.5	-0.5	1.0	0.3	0.9	-0.2	-0.6	-0.2	-0.5	-0.6	-0.5	-0.6	0.6	0.0	-0.7	0.5	-1.8
Cardiovascular Disease	0.2	0.5	1.3	0.9	0.8	0.8	0.8	0.2	1.1	0.3	0.8	-0.3	1.2	0.7	0.8	0.8	0.8	0.6	0.5	0.7	0.8	-0.1
Chronotype (morning person)	0.2	0.5	6.0	0.1	0.1	-0.7	0.2	0.7	0.7	0.2	0.4	-0.8	0.2	0.2	0.2	0.1	0.1	0.3	0.2	0.0	-2.4	1.2
Hearing difficulty/problems: Yes	0.2	0.3	1.1	-0.0	-0.0	0.2	0.1	-1.1	-0.0	0.9	-0.3	1.0	0.7	-0.1	0.0	-0.3	-0.0	0.2	0.3	-0.2	0.7	1.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	2.8	-0.0	-0.2	0.2	-0.0	-0.6	0.4	-0.2	-0.0	-0.5	0.5	-0.2	-0.1	0.0	-0.1	0.6	-0.3	-0.3	-0.8	1.7
Angina	0.2	0.3	4.4	0.5	0.2	0.3	0.1	-2.1	-0.2	-0.3	0.1	0.8	0.3	0.2	0.2	0.0	0.2	-0.1	-0.0	0.2	0.1	0.5
Medication: Co-codamol	0.2	0.2	0.7	-0.1	-0.2	-0.7	-0.5	0.8	0.4	-0.2	0.2	-0.8	0.6	-0.0	-0.2	-0.3	-0.4	0.4	-0.1	0.1	-0.1	-0.4
Diabetes (mother)	0.2	0.3	0.9	-0.2	-0.4	-0.5	-0.3	-0.4	-0.3	-1.0	-0.5	0.0	-0.6	-0.4	-0.4	-0.2	-0.4	-0.2	-0.7	-0.5	-0.7	0.9
Leg fat-free mass (left)	0.2	0.9	5.2	-1.2	-0.9	-0.8	-1.2	1.3	-0.7	-0.1	-0.7	-0.5	-0.4	-1.0	-1.0	-0.9	-1.1	-0.3	-0.6	-0.7	-0.7	-2.3
Trunk fat percentage	0.2	0.7	4.8	0.4	0.4	-0.0	0.5	2.2	0.7	0.8	0.5	-0.5	1.5	0.4	0.4	1.1	0.5	-0.3	0.6	0.3	-0.4	-1.5
Medication: Atenolol	0.2	0.2	1.4	0.4	0.2	0.1	0.2	0.5	-0.1	-0.5	0.2	1.2	-0.7	0.1	0.2	-0.1	0.2	-0.5	-0.1	0.1	0.1	-0.8
Chronic bronchitis/emphysema (father)	0.2	0.2	1.6	-0.2	-0.1	-0.2	0.1	0.2	-0.3	-0.0	-0.1	0.1	-0.1	-0.0	-0.1	-0.1	-0.0	0.9	-0.2	-0.4	-1.1	1.3
Body mass index (BMI)	0.2	1.0	7.0	-0.6	-0.9	-1.1	-1.1	0.1	-0.6	-0.3	-1.1	-0.6	-0.3	-0.9	-1.0	-0.7	-1.0	-1.1	-0.7	-1.0	0.1	-2.6
Impedance of leg (left)	0.2	1.1	5.5	1.0	0.8	0.7	1.1	2.4	1.1	0.4	1.2	-0.4	1.0	0.8	0.9	1.2	1.0	0.6	0.6	0.6	-0.3	1.6
Leg predicted mass (left)	0.2	1.1	5.7	-1.3	-1.0	-0.9	-1.3	1.2	-0.7	-0.2	-0.8	-0.6	-0.4	-1.1	-1.1	-0.9	-1.2	-0.3	-0.6	-0.7	-0.8	-2.4
Number of incorrect matches in round	0.2	0.3	2.0	0.2	0.2	0.2	0.3	1.4	0.6	0.2	0.4	-0.2	-0.1	0.3	0.2	0.5	0.3	0.2	0.2	0.0	-1.3	-0.5
Alcohol usually taken with meals	0.2	0.3	2.7	-0.6	-0.2	-0.3	-0.2	1.6	-0.2	0.3	0.1	0.0	0.7	-0.2	-0.2	0.3	-0.2	0.1	0.1	-0.1	-0.8	0.0
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.3	-0.3	-0.5	-0.7	-0.6	1.1	0.4	0.1	0.3	-0.3	-0.6	-0.3	-0.5	-0.4	-0.7	0.5	-0.1	-0.5	-0.0	-0.4
Heart attack	0.2	0.2	1.4	0.2	0.4	0.2	0.2	-0.7	0.4	-0.7	0.3	-0.3	1.2	0.4	0.3	0.3	0.2	-0.5	-0.0	0.6	0.1	0.5
Illnesses of siblings	0.2	0.2	2.0	-0.2	0.0	-0.1	0.3	0.8	-0.2	-0.5	0.2	0.4	0.5	-0.1	0.1	0.1	0.2	-0.3	-0.3	-0.1	0.7	1.4
Hip circumference	0.2	0.7	6.1	-0.2	-0.3	-0.3	-0.4	1.3	0.3	0.5	-0.2	-1.7	0.5	-0.3	-0.4	0.1	-0.4	-0.5	0.0	-0.3	-0.6	-2.5
Worrier / anxious feelings	0.2	0.4	2.3	-0.0	0.1	0.3	0.2	1.2	0.9	0.6	0.6	-1.5	0.4	0.0	0.0	0.3	0.1	0.8	0.2	-0.2	-1.0	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	2.0	-0.1	0.8	1.2	0.6	0.6	0.9	0.8	1.4	0.0	0.6	0.9	0.8	0.5	0.7	1.3	0.9	1.0	0.3	0.2
Standing height	0.2	1.8	19.2	-1.3	-0.8	-0.6	-0.9	4.4	-0.4	-0.5	0.2	-1.1	-0.3	-1.0	-0.8	-0.4	-0.8	0.3	-0.7	-0.5	-2.2	-1.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.2	1.4	0.1	-0.0	-0.5	-0.2	-0.2	-0.4	-1.2	-0.1	-0.2	-0.1	0.0	-0.1	-0.0	-0.1	1.1	-0.5	-0.0	1.0	-0.4
Blood clot in the leg (DVT)	0.2	0.2	0.8	-0.2	-0.5	-0.8	-0.5	-0.2	-0.4	-0.3	-0.5	-0.1	-0.2	-0.6	-0.5	-0.6	-0.6	-0.2	-0.4	-0.3	0.9	0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	-0.8	-0.6	-0.7	-0.7	-0.2	-0.5	-0.2	-0.4	-0.9	-0.8	-0.6	-0.6	0.2	-0.7	0.6	-0.4	-0.4	0.2	-0.3
Shortness of breath walking on level ground	0.2	0.3	1.5	-0.4	0.0	-0.0	0.0	0.7	0.2	-0.3	0.2	-1.1	0.4	0.1	-0.0	0.3	-0.2	1.2	-0.1	0.0	-0.7	-1.0
Eye problems/disorders: None of the above	0.2	0.2	1.4	0.2	0.4	0.2	0.2	-0.4	0.4	-0.2	0.3	0.9	-0.0	0.3	0.3	-0.2	0.5	-0.5	0.2	0.7	1.2	-0.0
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.6	-0.2	-0.3	-0.2	-0.4	0.5	0.1	-0.3	-0.1	-0.9	0.3	-0.3	-0.3	-0.3	-0.4	1.3	-0.2	-0.0	0.4	-0.5
Neck or shoulder pain in last month	0.2	0.3	1.9	0.4	-0.2	-0.1	-0.2	-0.6	-0.6	-0.5	-0.6	1.4	-1.1	-0.2	-0.2	-0.1	-0.1	0.2	-0.4	-0.3	0.6	0.5
Angina (self-reported)	0.2	0.3	4.3	0.4	0.2	0.2	0.1	-2.1	-0.3	-0.4	0.1	0.7	0.3	0.2	0.2	0.1	0.2	-0.0	-0.1	0.2	0.0	0.8
Migraine (self-reported)	0.2	0.2	1.1	0.3	0.2	0.2	0.1	0.8	0.5	0.4	0.1	-0.1	0.9	0.1	0.2	0.1	0.1	0.6	0.3	0.3	-0.7	1.0
Medication: Omeprazole	0.2	0.3	1.4	-0.0	-0.4	-0.7	-0.3	-0.2	-0.2	-1.2	-0.7	-0.5	-0.3	-0.5	-0.4	-0.4	-0.3	0.9	-0.7	-0.4	-0.4	0.1
Whole body fat mass	0.2	0.7	4.0	-0.4	-0.6	-0.8	-0.6	1.6	-0.2	-0.1	-0.4	-0.8	0.3	-0.6	-0.6	-0.1	-0.6	-0.8	-0.4	-0.6	-1.0	-2.0
Pulse rate, automated reading	0.2	0.7	4.2	-0.5	-0.7	-0.7	-1.0	0.0	0.1	-0.8	-0.2	-2.0	0.0	-0.5	-0.7	-0.8	-1.0	0.1	-0.6	-0.3	-2.1	-0.2
Had major operations	0.2	0.2	1.0	0.5	0.3	0.5	0.4	0.4	0.2	-0.2	0.5	0.0	1.0	0.3	0.3	0.3	0.4	0.3	-0.0	0.2	0.7	-1.0
Hypertension (Self-reported)	0.2	0.7	1.4	1.0	0.9	0.9	1.2	0.1	1.1	0.3	0.8	0.2	0.8	0.9	1.0	1.1	1.1	0.2	0.7	0.9	-0.5	-0.1
Illnesses of father: Heart disease	0.2	0.3	1.8	0.5	0.2	0.4	0.2	-0.4	0.5	1.0	-0.1	-0.1	-0.5	0.3	0.2	0.4	0.2	-0.1	0.6	0.3	1.3	-0.8
Leg fat-free mass (right)	0.2	1.3	4.9	-1.4	-1.1	-1.0	-1.4	1.4	-0.8	-0.3	-0.9	-0.7	-0.6	-1.2	-1.2	-1.1	-1.3	-0.7	-0.8	-0.9	-1.0	-2.2
Commuting to job workplace: Walk	0.2	0.2	1.5	0.0	-0.0	-0.1	-0.3	-1.1	-0.5	-0.4	-0.1	-0.0	-0.2	0.0	-0.1	0.0	-0.2	-0.6	-0.0	0.1	1.2	0.4
Leg predicted mass (right)	0.2	1.3	5.2	-1.4	-1.2	-1.0	-1.4	1.4	-0.8	-0.3	-0.9	-0.6	-0.7	-1.2	-1.2	-1.2	-1.3	-0.7	-0.8	-0.9	-0.9	-2.3
Wears glasses or contact lenses	0.2	0.2	1.4	0.5	-0.0	0.4	0.1	-0.2	0.6	1.0	-0.2	-0.7	-0.3	-0.1	-0.0	-0.2	0.1	-1.2	0.3	-0.3	-0.5	-0.2
Medication: Bendroflumethiazide	0.2	0.4	2.0	0.5	0.2	-0.5	0.2	-0.8	-0.0	-1.0	-0.1	0.2	-0.5	0.2	0.2	0.1	0.1	-1.4	-0.3	0.2	0.7	1.2
Diastolic blood pressure, automated reading	0.2	0.5	4.7	0.1	-0.5	-0.7	-0.6	0.7	0.6	0.3	0.1	-0.5	0.3	-0.3	-0.5	-0.5	-0.6	-1.1	-0.1	-0.4	-2.2	-0.8
Ever depressed for a whole week	0.2	0.2	2.6	0.0	-0.0	-0.2	-0.0	0.1	0.6	0.1	0.1	-1.6	-0.3	0.0	-0.1	0.1	0.0	0.3	-0.0	-0.1	0.5	-0.8
Pain experienced in last month	0.2	0.4	0.8	0.1	0.7	0.6	0.8	-0.6	0.1	0.1	0.7	0.6	0.9	0.7	0.7	0.5	0.7	0.7	0.5	0.7	0.8	0.7
Basal cell carcinoma (self-reported)	0.2	0.3	3.2	1.1	0.2	-0.1	-0.1	-0.3	-0.1	-0.6	0.1	0.1	-0.4	0.2	0.1	-0.2	0.0	-0.5	-0.1	0.2	-0.2	1.8
Heart attack/myocardial infarction (self-reported)	0.2	0.2	1.7	0.1	0.5	0.3	0.2	-0.5	0.4	-0.6	0.5	-0.4	1.3	0.5	0.4	0.5	0.2	-0.1	0.1	0.7	-0.0	0.3
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	1.3	0.1	-0.4	-0.6	-0.4	-0.3	-0.4	-0.3	-0.5	-0.1	0.1	-0.4	-0.4	-0.5	-0.4	-0.6	-0.3	-0.3	1.1	-0.3
Leg fat mass (left)	0.2	0.7	3.8	-0.3	-0.8	-1.0	-0.9	0.9	-0.2	-0.2	-0.6	-1.1	0.0	-0.8	-0.8	-0.3	-0.8	-1.2	-0.6	-0.9	-0.8	-2.0
Blood Platelet Count	0.1	0.7	7.8	0.2	0.2	0.4	0.4	-2.8	-0.2	0.6	-0.3	1.4	-0.7	0.0	0.2	0.2	0.5	1.0	0.2	-0.1	0.4	0.4
Blood Red Count	0.1	0.8	3.0	-0.7	-0.9	-1.5	-0.8	1.4	-0.4	-1.7	-0.6	0.1	0.2	-0.9	-0.9	-0.9	-0.9	0.0	-1.3	-1.1	0.1	0.2
Height	0.1	2.7	19.6	-1.5	-1.4	-1.6	-1.4	4.4	-1.0	-1.1	-0.4	-0.8	-0.6	-1.6	-1.4	-0.8	-1.4	0.5	-1.4	-1.3	-3.0	-0.1
Hair Pigment	0.1	2.9	5.3	1.6	1.8	2.3	1.7	1.6	2.3	2.1	1.6	-1.1	2.2	1.8	1.7	2.0	1.7	-0.3	2.0	1.6	-0.6	0.7
Hand grip strength (left)	0.1	0.4	2.4	-0.3	-0.4	0.0	-0.5	-1.5	-0.5	0.4	-0.4	0.5	-0.6	-0.4	-0.4	-0.7	-0.4	-0.3	-0.0	-0.1	-1.5	-0.2
High blood pressure	0.1	0.3	0.7	0.9	0.5	0.6	0.7	0.4	0.9	0.1	0.3	0.0	0.4	0.4	0.6	0.8	0.7	-0.2	0.3	0.5	-0.2	-0.7
Trunk fat mass	0.1	0.6	4.7	-0.2	-0.3	-0.6	-0.3	2.2	0.1	0.2	-0.0	-0.9	0.8	-0.3	-0.3	0.3	-0.2	-0.5	-0.1	-0.3	-0.9	-2.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.4	0.2	0.0	0.3	-0.1	0.9	0.9	0.4	0.2	-1.2	0.7	0.1	-0.1	0.2	-0.1	-0.2	0.2	0.0	-0.0	-0.3
Forced vital capacity (FVC)	0.1	0.5	1.2	0.4	0.7	1.1	0.5	-0.6	0.4	0.2	1.0	0.6	0.0	0.7	0.6	0.6	0.7	1.0	0.6	0.8	0.9	0.5
Qualifications: None of the above	0.1	0.2	0.8	0.4	-0.1	-0.2	-0.1	-0.1	-0.2	0.7	0.2	0.4	-0.9	0.0	-0.0	0.2	-0.3	0.5	0.3	-0.0	-0.8	-0.8
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	2.3	0.1	-0.0	-0.1	-0.1	0.3	-0.0	-0.5	-0.0	-0.2	0.1	0.2	-0.0	-0.1	-0.0	0.2	-0.2	-0.0	1.5	-0.8
Medication: Simvastatin	0.1	0.2	1.3	0.1	-0.2	-0.3	-0.1	-1.1	-0.3	-0.3	-0.3	0.7	-0.7	-0.4	-0.3	0.1	-0.1	0.1	-0.4	-0.3	0.3	-0.4
Arm fat percentage (right)	0.1	0.2	2.4	-0.0	-0.3	-0.7	-0.3	0.2	-0.2	0.1	-0.5	-0.2	0.3	-0.3	-0.3	0.1	-0.2	-0.3	-0.2	-0.5	0.6	-1.5
Father’s age at death	0.1	0.2	2.1	-0.0	0.1	-0.1	-0.2	-1.4	0.0	-0.7	0.1	-0.3	0.0	0.2	0.1	-0.2	-0.2	0.8	-0.1	0.3	-0.3	-0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	1.3	-0.3	0.2	0.5	-0.0	-0.3	0.2	-0.1	0.8	0.5	-0.1	0.3	0.2	-0.0	0.1	1.1	0.2	0.5	0.7	0.5
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.2	-0.4	-0.2	-0.7	-0.3	-1.1	-0.7	-0.1	-0.5	-0.2	0.2	-0.2	-0.2	-0.4	-0.3	0.3	-0.1	-0.1	0.2	-0.1
Peak expiratory flow (PEF)	0.1	0.2	0.9	0.3	0.2	-0.0	0.1	0.2	0.3	-0.5	0.6	0.9	-0.1	0.1	0.2	0.0	0.2	0.1	-0.1	0.2	0.5	0.9
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.6	-0.1	-0.3	-0.3	-0.4	0.8	-0.0	0.0	-0.4	-0.3	-0.0	-0.3	-0.3	-0.2	-0.3	0.1	-0.2	-0.3	0.1	-0.5
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	1.6	-0.2	-0.1	0.4	-0.2	-0.1	-0.1	0.5	0.1	0.7	-0.9	-0.1	-0.1	-0.4	-0.1	1.3	0.2	-0.0	0.8	-0.1
Birth weight	0.1	0.2	1.9	-0.2	0.1	-0.1	0.1	0.6	-0.1	-0.8	0.5	0.1	-0.0	0.1	0.1	-0.2	0.2	0.7	-0.3	0.0	-1.4	-0.8
Body fat percentage	0.1	0.5	2.8	0.4	0.2	-0.3	0.2	1.7	0.5	0.4	0.3	-0.8	1.2	0.2	0.2	0.8	0.3	-0.3	0.3	0.1	-0.5	-1.5
Leg fat percentage (right)	0.1	0.2	1.1	0.4	-0.2	-0.7	-0.3	0.5	0.4	-0.1	0.0	-1.0	0.6	-0.2	-0.2	0.2	-0.2	-0.4	-0.1	-0.2	-0.4	-1.0
Health satisfaction	0.1	0.2	1.7	0.1	-0.0	0.4	0.0	1.3	0.7	0.1	0.3	-0.4	-0.3	0.0	-0.0	-0.2	-0.1	-0.2	0.1	-0.0	0.4	-0.4
Heart disease (mother)	0.1	0.1	0.5	0.3	-0.0	-0.2	0.2	-0.0	0.1	-0.6	-0.1	0.2	-0.7	0.1	0.0	0.1	0.1	-0.4	-0.3	-0.2	-0.3	0.2
Leg fat mass (right)	0.1	0.6	3.4	-0.2	-0.6	-0.8	-0.7	0.9	-0.1	-0.1	-0.5	-1.0	0.2	-0.6	-0.7	-0.2	-0.7	-0.8	-0.5	-0.7	-0.7	-1.9
Comparative height size at age 10	0.1	0.4	2.2	-0.1	0.1	0.2	0.3	1.3	0.5	-0.1	0.8	-1.5	0.5	0.0	0.2	0.7	0.2	0.7	0.1	0.3	-0.6	0.9
Arm fat percentage (left)	0.1	0.3	3.8	0.3	0.1	-0.3	0.1	0.6	0.1	0.4	-0.0	-0.1	0.7	0.1	0.1	0.5	0.2	-0.3	0.2	0.0	0.6	-2.0
Friendships satisfaction	0.1	0.1	1.0	0.3	0.1	0.0	0.2	0.6	0.3	0.7	-0.0	-0.0	0.1	0.1	0.1	0.2	0.2	0.5	0.3	-0.1	-1.0	0.4
Arm fat mass (left)	0.1	0.6	6.3	-0.3	-0.4	-0.7	-0.5	1.3	-0.1	0.2	-0.4	-0.6	0.3	-0.4	-0.5	-0.1	-0.4	-0.7	-0.2	-0.5	-0.4	-2.5
High cholesterol (Self-reported)	0.1	0.2	1.7	-0.1	-0.2	0.0	-0.0	0.1	-0.0	-0.4	-0.1	1.3	-1.0	-0.2	-0.2	0.1	-0.0	1.1	-0.3	-0.3	-0.1	-0.5
Leg fat percentage (left)	0.1	0.4	1.4	0.1	-0.5	-0.9	-0.5	0.6	0.2	-0.3	-0.2	-1.2	0.4	-0.4	-0.5	-0.0	-0.5	-1.2	-0.4	-0.6	-0.8	-1.0
Myopia	0.1	0.2	0.9	-0.3	0.4	-0.1	0.2	0.9	0.6	-0.3	0.4	0.1	0.1	0.4	0.4	-0.1	0.4	-1.0	0.2	0.5	-0.1	0.3
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.6	-0.7	-0.5	-0.5	-0.6	0.2	-0.8	-0.3	-0.3	-0.3	-0.5	-0.4	-0.6	-0.6	-0.6	0.2	-0.4	-0.5	0.3	0.6
Blood Eosinophil Count	0.0	0.3	2.2	0.5	0.1	0.1	-0.0	-0.4	0.4	0.7	0.4	-0.3	-0.0	0.2	0.1	0.1	0.1	-1.2	0.4	0.0	-0.1	-1.5
Tanning	0.0	0.5	2.0	1.2	0.7	0.4	0.6	-0.4	1.2	-0.8	1.4	-0.0	0.5	0.8	0.8	0.3	0.6	0.2	0.1	0.7	0.0	1.0
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.4	-0.2	0.3	0.2	0.5	0.3	0.1	0.4	-0.1	0.5	0.1	0.3	0.3	0.2	0.6	-0.1	0.3	0.2	0.2	0.0
Allergy	0.0	0.1	0.9	0.3	-0.1	0.1	-0.2	-0.1	-0.1	-0.2	-0.1	-0.5	0.1	-0.1	-0.1	-0.2	-0.3	0.0	-0.0	-0.0	-0.9	-0.5

Hub : Genes

AMPH

Models

Trait associations