[Hub]/) : Traits : Heel T-Score :

chr1:92,277,843-93,942,442

Best TWAS P=1.28e-08 · Best GWAS P=5.49e-09 conditioned to 0.0819

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial EVI5 0.08 0.08 lasso 10 0.12 9.5e-10 5.4 5.5 4.3e-08 0.88 0.05 0.95 FALSE
2 GTEx Brain Caudate basal ganglia EVI5 0.10 0.00 enet 19 0.01 1.7e-01 5.5 5.4 6.2e-08 0.82 0.04 0.64 FALSE
3 GTEx Brain Hypothalamus EVI5 0.16 0.12 lasso 13 0.05 2.1e-02 5.4 5.5 3.6e-08 1.00 0.02 0.84 FALSE
4 GTEx Breast Mammary Tissue EVI5 0.07 0.06 lasso 4 0.07 2.3e-04 5.5 5.5 4.8e-08 0.99 0.02 0.97 FALSE
5 GTEx Colon Sigmoid EVI5 0.13 0.16 lasso 3 0.12 7.0e-05 5.5 5.5 3.6e-08 1.00 0.02 0.98 FALSE
6 GTEx Heart Atrial Appendage EVI5 0.09 0.06 lasso 7 0.05 4.2e-03 5.5 5.6 2.6e-08 1.00 0.02 0.94 FALSE
7 GTEx Heart Left Ventricle EVI5 0.07 0.11 lasso 5 0.08 7.7e-05 5.5 5.5 4.2e-08 0.99 0.02 0.98 FALSE
8 GTEx Uterus EVI5 0.23 0.12 enet 27 0.16 4.3e-04 5.5 5.2 2.6e-07 0.90 0.04 0.87 FALSE
9 GTEx Whole Blood EVI5 0.03 0.01 lasso 2 0.01 6.8e-02 5.5 5.3 9.0e-08 0.96 0.03 0.96 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma EVI5 0.03 0.03 lasso 4 0.04 3.6e-09 3.7 5.2 2.2e-07 0.89 0.03 0.97 FALSE
11 The Cancer Genome Atlas Glioblastoma Multiforme EVI5 0.14 0.04 blup 93 0.06 8.9e-03 4.6 5.7 1.3e-08 0.88 0.03 0.74 TRUE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma EVI5 0.08 0.04 blup 96 0.06 8.6e-08 3.6 5.4 5.7e-08 0.88 0.04 0.96 FALSE
13 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EVI5 0.04 0.02 blup 96 0.04 1.4e-03 4.5 5.5 4.0e-08 0.85 0.03 0.70 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma EVI5 0.18 0.16 lasso 7 0.15 2.0e-16 5.5 5.4 6.8e-08 0.98 0.02 0.98 FALSE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EVI5 0.04 0.04 blup 93 0.03 4.8e-04 3.7 5.2 2.4e-07 0.85 0.10 0.85 FALSE
16 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma EVI5 0.05 0.02 blup 96 0.03 2.3e-03 4.0 5.4 7.9e-08 0.83 0.09 0.71 FALSE
17 The Cancer Genome Atlas Pancreatic Adenocarcinoma EVI5 0.10 0.06 blup 94 0.08 2.9e-04 5.5 5.5 4.5e-08 0.92 0.02 0.96 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma EVI5 0.06 0.10 blup 94 0.10 1.7e-10 5.5 5.6 2.6e-08 0.92 0.01 0.99 FALSE